Chemical Brain Injury

Chemical Brain Injury

Author: Kaye H. Kilburn

Publisher: Van Nostrand Reinhold Company

Published: 1998

Total Pages: 424

ISBN-13:

DOWNLOAD EBOOK

chemical brain injury Kaye H. Kilburn, M.D. The idea that the brain is the most susceptible body organ to the adverse effects of chemicals seemed a remote possibility a decade or two ago. Among the skeptics was Dr. Kaye H. Kilburn. Well-known in Environmental Medicine and Occupational Health, he had demonstrated that airways-obstruction caused the Monday-morning asthma from cotton dust in textile workers that led to the Cotton Dust Standard. He showed how asbestos scarred the lungs small airways to trap air and reduce vital capacity, and that welding fumes, aluminum refining, diesel exhaust, and formaldehyde caused asthma by narrowing small airways. These workers complaints of memory loss, inability to concentrate, dizziness, lightheadedness, and loss of balance led Dr. Kilburn to consider how to measure brain functions. He borrowed and adapted tests and built devices to measure key brain activities, and learned to find out how symptoms predicted losses of balance, quickness, and strength, and loss of vision for color and form. Nearly 300 patients who had been exposed to chemicals were evaluated for diagnosis and nearly 4,000 people who had been exposed in groups were evaluated for chemical effects. Statistical analysis of patients gathered from individuals and groups in cities, towns, and rural areas provided complementary insights into the effects of chemicals. Chemical Brain Injury focuses on how common and abundant chemicals affect the brain. It synthesizes endeavors to assess the effects of chemicals that were gathered over 15 years and published in 30 widely-scattered papers. Included are effects of chlorine, hydrogen sulfide, chlordane, arsenic, trichoroethylene, PCBs, hydrochloric acid, and diesel exhaust. To understand how individuals and populations respond to chemicals, it considers the effects of aging, of years of school completed, and of sex, height, weight, and other factors. The book addresses such issues as: The infrequency of chemically unaffected populations in the United States Mechanisms of brain damage from chemicals Prognosis and therapy The last section examines the social context and discusses such matters as: The future of neurotoxicology, including needs and responsibility Legal proceedings Social changes Chemical Brain Injury is the definitive volume on the adverse effects of chemical exposure on the human brain.


Environmental Neurotoxicology

Environmental Neurotoxicology

Author: National Research Council

Publisher: National Academies Press

Published: 1992-02-01

Total Pages: 167

ISBN-13: 0309045312

DOWNLOAD EBOOK

Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.


Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury

Author: Daniel Laskowitz

Publisher: CRC Press

Published: 2016-04-21

Total Pages: 388

ISBN-13: 1498766579

DOWNLOAD EBOOK

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme


Biomarkers for Traumatic Brain Injury

Biomarkers for Traumatic Brain Injury

Author: Svetlana Dambinova

Publisher: Royal Society of Chemistry

Published: 2012-05-24

Total Pages: 247

ISBN-13: 1849734747

DOWNLOAD EBOOK

Due to injuries sustained in sports and in combat, interest in TBI has never been greater. Biomarkers for Traumatic Brain Injury will fulfil a gap in our understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging. This knowledge will be useful for all researchers and clinicians interested in the biochemical and structural sequelae underpinning clinical manifestations of TBI and help guide appropriate patient management. Current and prospective biomarkers for the assessment of traumatic brain injury (TBI), particularly mild TBI, are examined using a multidisciplinary approach involving biochemistry, molecular biology, and clinical chemistry. The book incorporates presentations from outstanding researchers and clinicians in the area and describes advanced proteomic and degradomic technologies in the development of novel biomarker assays. For practical purposes, the focus of this volume is on detection of blood-based biomarkers to improve diagnostic certainty of mild TBI in conjunction with radiological and clinical findings. It represents contributions from internationally-recognized researchers at the forefront of traumatic brain injury many of whom are recipients of grants and contracts from the United States Department of Defense for research specifically on developing diagnostic tests for TBI. The book will be essential reading for scientists, pharmacologists, chemists, medical and graduate students.


Sports-Related Concussions in Youth

Sports-Related Concussions in Youth

Author: National Research Council

Publisher: National Academies Press

Published: 2014-02-04

Total Pages: 215

ISBN-13: 0309288037

DOWNLOAD EBOOK

In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.


Traumatic Brain and Spinal Cord Injury

Traumatic Brain and Spinal Cord Injury

Author: Cristina Morganti-Kossmann

Publisher: Cambridge University Press

Published: 2012-07-19

Total Pages: 361

ISBN-13: 1107007437

DOWNLOAD EBOOK

Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.


Brain Neurotrauma

Brain Neurotrauma

Author: Firas H. Kobeissy

Publisher: CRC Press

Published: 2015-02-25

Total Pages: 718

ISBN-13: 1466565993

DOWNLOAD EBOOK

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.


Coping with Concussion and Mild Traumatic Brain Injury

Coping with Concussion and Mild Traumatic Brain Injury

Author: Diane Roberts Stoler Ed.D.

Publisher: Penguin

Published: 2013-11-05

Total Pages: 400

ISBN-13: 1101631619

DOWNLOAD EBOOK

A comprehensive guide for improving memory, focus, and quality of life in the aftermath of a concussion. Often presenting itself after a head trauma, concussion— or mild traumatic brain injury (mTBI)— can cause chronic migraines, depression, memory, and sleep problems that can last for years, referred to as post concussion syndrome (PCS). Neuropsychologist and concussion survivor Dr. Diane Roberts Stoler is the authority on all aspects of the recovery process. Coping with Concussion and Mild Traumatic Brain Injury is a lifeline for patients, parents, and other caregivers.


Neurotrauma

Neurotrauma

Author: Raj K. Narayan

Publisher: McGraw-Hill

Published: 1996

Total Pages: 1558

ISBN-13: 9780070456624

DOWNLOAD EBOOK

This reference is a comprehensive work in the field of neurotrauma and critical care. It incorporates the fields of head injury, spinal injury and basic neurotrauma research into one source. The major emphasis is on the treatment of patients with head and spinal cord injury, including the management of all other problems that bear upon the care of these patients.


Living with Brain Injury

Living with Brain Injury

Author: Richard C. Senelick

Publisher: Encompass Health Press

Published: 2001

Total Pages: 0

ISBN-13: 9781891525094

DOWNLOAD EBOOK

"The new, updated edition of the renowned classic - complete with cutting edge neuroplaticity and exciting experimental rehabilitation research! Living with Brain Injury will help readers - both families of patients and professionals alike - through new, uncharted territory of brain rehabilitation, a world where people we love may change before our eyes, physically, mentally, and emotionally"--Amazon