Multiple Sclerosis and Associated Demyelinating Disorders, An Issue of Neuroimaging Clinics of North America, E-Book
Multiple Sclerosis and Associated Demyelinating Disorders, An Issue of Neuroimaging Clinics of North America, E-Book

Author: Frederik Barkhof

Publisher: Elsevier Health Sciences

Published: 2024-07-01

Total Pages: 209

ISBN-13: 0443128901

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In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology's 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging. - Contains 12 relevant, practice-oriented topics including diagnostic criteria for MS, NMOSD and MOGAD; routine MRI protocol and standardization in CNS demyelinating diseases; spinal cord imaging in MS and related disorders; treatment monitoring in MS: efficacy and safety; cognitive impairment in MS and related disorders; and more. - Provides in-depth clinical reviews on multiple sclerosis and associated demyelinating disorders, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Multiple Sclerosis
Multiple Sclerosis

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-08-10

Total Pages: 457

ISBN-13: 0309072859

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Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Evidence-Based Vascular Neuroimaging, An Issue of Neuroimaging Clinics of North America
Evidence-Based Vascular Neuroimaging, An Issue of Neuroimaging Clinics of North America

Author: Ajay Malhotra

Publisher: Elsevier Health Sciences

Published: 2021-05-05

Total Pages: 145

ISBN-13: 0323775527

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This issue of Neuroimaging Clinics focuses on Evidence-Based Vascular Neuroimaging and is edited by Drs. Ajay Malhotra and Dheeraj Gandhi. Articles will include: Unruptured Intracranial Aneurysms: Duration, Frequency and Modality Used for Surveillance; Vasospasm: Role of Imaging in Detection and Monitoring Treatment; Extracranial Vascular Disease: Carotid Stenosis and Plaque Imaging; Subarachnoid Hemorrhage: Distribution and Role of Imaging; Acute Ischemic Stroke: MRI-based Paradigms; Imaging of Intracranial Hemorrhage (Non-subarachnoid Hemorrhage); Brain Arteriovenous Malformations: The Role of Imaging in Treatment Planning and Monitoring Response; Intracranial Vascular Disease and Vessel Wall Imaging; Acute Ischemic Stroke: CT/CTA/CTP and Their Role; Imaging for Treated Aneurysms (including clipping, coiling, stents, flow-diverters); and more!

Neurodegeneration
Neurodegeneration

Author: Anthony Schapira

Publisher: John Wiley & Sons

Published: 2017-02-13

Total Pages: 1078

ISBN-13: 1118661915

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This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors

The Neurobiology of Multiple Sclerosis
The Neurobiology of Multiple Sclerosis

Author:

Publisher: Academic Press

Published: 2007-06-07

Total Pages: 759

ISBN-13: 0080544274

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Multiple sclerosis (MS) is an immune-mediated neurodegenerative disorder of the human central nervous system (CNS) which usually affects young adults with certain genetic backgrounds who are then exposed to certain precipitating environmental antigen(s). Despite major advances of the past two decades in understanding the pathophysiology of MS, and in spite of the introduction of new immunomodulatory and immuno-suppressive agents which may slow down disease progression and delay the onset of disability, the "cause and the "cure for MS remain elusive. This volume of International Review of Neurobiology focuses on MS and related disorders. The volume can be divided into various sections with the main emphasis on MS pathogenesis, clinical features and epidemiology, neuroimaging, and treatment. The ultimate goal of this book is to encourage further research into the pathogenesis of this elusive disease.

White Matter Dementia
White Matter Dementia

Author: Christopher M. Filley

Publisher: Cambridge University Press

Published: 2016-04-28

Total Pages: 231

ISBN-13: 1107035414

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Presenting the novel concept of white matter dementia, this unique book offers hope for a better understanding and treatment of dementia.

Multiple Sclerosis, Mad Cow Disease and Acinetobacter
Multiple Sclerosis, Mad Cow Disease and Acinetobacter

Author: Alan Ebringer

Publisher: Springer

Published: 2014-11-19

Total Pages: 208

ISBN-13: 3319027352

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The aim of this book is to publicise and bring to a wider audience the concept that the cause of two neurological diseases, namely multiple sclerosis (MS) and “mad cow disease” also known as “bovine spongiform encephalopathy” are related through exposure to a common microbe Acinetobacter which is found in human sinuses, on skin and in the soil. An infection is the cause of a neurological disease in man and in animals. Elevated levels of antibodies to Acinetobacter have been found in multiple sclerosis patients as well as in ruminants who have been described as suffering from “mad cow disease” following exposure to contaminated feed supplements. The overall objective and scope of this book is to inform the audience, the reader, that multiple sclerosis may be linked to a microbe Acinetobacter which carries molecular structures resembling myelin, the outer sheath covering of neurons.

Imaging of White Matter, An Issue of Radiologic Clinics of North America, E-Book
Imaging of White Matter, An Issue of Radiologic Clinics of North America, E-Book

Author: Sangam Kanekar

Publisher: Elsevier Health Sciences

Published: 2014-03-28

Total Pages: 241

ISBN-13: 0323287212

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White matter lesions have been always challenging for general as well as neuroradiologits. Any disease process in the brain or body can affect white matter, making it very difficult to pinpoint the diagnosis. However the application of the proper algorithmic approach, pattern of distribution, and study of the morphology of these lesions makes it possible to limit the differential diagnosis and, many times, pinpoint specific diagnosis. Advancement of various imaging techniques predominately in MR (MR spectroscopy, MR perfusion, diffusion tensor imaging (DTI). functional MR) along with PET has further improved our understanding of these disease processes. However, most of these techniques are new and not well understood by every physician. This issue will cover the topics necessary to master these techniques.