Computers in Systematic Biology
Author: Larry E. Morse
Publisher:
Published: 1971
Total Pages: 66
ISBN-13:
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From Taxonomy to Phylogenetics – Life and Work of Willi Hennig
Author: Michael Schmitt
Publisher: BRILL
Published: 2013-04-15
Total Pages: 224
ISBN-13: 9004219293
DOWNLOAD EBOOKBiological Systematics has changed dramatically during the past 60 years from a handicraft or art to an accepted branch of science proper, due to the work of Willi Hennig, who was born in 1913. The scientific method of reconstructing phylogenetic relationships of organisms bases on Hennig's approach, the "Phylogenetic Systematics". The method is now so widely accepted and applied that it can firmly be regarded a paradigm, named 'cladistics'. In contrast, the life and personality of its founder is remarkably little known in the scientific community. The present book offers a detailed biography of Willi Hennig, and traces the roots of his thinking from his schooldays until his death in 1976. Some outstanding academic teachers and friends of his are introduced, too. The book offers an insight into the historical development of a 'scientific revolution', and highlights the life and the work of a 'cautious revolutioniser' in a Germany of dictatorship, war, and separation.
Systematic Biology
Author:
Publisher: National Academies
Published: 1969
Total Pages: 656
ISBN-13:
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Author: James R. Valcourt
Publisher: Bloomsbury Publishing USA
Published: 2017-02-07
Total Pages: 289
ISBN-13: 1632860317
DOWNLOAD EBOOKA brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing. SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly. Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before. In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.
Biological Computation
Author: Ehud Lamm
Publisher: CRC Press
Published: 2011-05-25
Total Pages: 332
ISBN-13: 1420087967
DOWNLOAD EBOOKThe area of biologically inspired computing, or biological computation, involves the development of new, biologically based techniques for solving difficult computational problems. A unified overview of computer science ideas inspired by biology, Biological Computation presents the most fundamental and significant concepts in this area. In the book
Systems Biology
Author: Edda Klipp
Publisher: John Wiley & Sons
Published: 2016-03-28
Total Pages: 504
ISBN-13: 3527675663
DOWNLOAD EBOOKThis advanced textbook is tailored for an introductory course in Systems Biology and is well-suited for biologists as well as engineers and computer scientists. It comes with student-friendly reading lists and a companion website featuring a short exam prep version of the book and educational modeling programs. The text is written in an easily accessible style and includes numerous worked examples and study questions in each chapter. For this edition, a section on medical systems biology has been included.
Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology
Author: Hamid R Arabnia
Publisher: Morgan Kaufmann
Published: 2015-08-11
Total Pages: 670
ISBN-13: 0128026464
DOWNLOAD EBOOKEmerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. - Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. - Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. - Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.
Frontiers in Computational and Systems Biology
Author: Jianfeng Feng
Publisher: Springer Science & Business Media
Published: 2010-06-14
Total Pages: 411
ISBN-13: 1849961964
DOWNLOAD EBOOKBiological and biomedical studies have entered a new era over the past two decades thanks to the wide use of mathematical models and computational approaches. A booming of computational biology, which sheerly was a theoretician’s fantasy twenty years ago, has become a reality. Obsession with computational biology and theoretical approaches is evidenced in articles hailing the arrival of what are va- ously called quantitative biology, bioinformatics, theoretical biology, and systems biology. New technologies and data resources in genetics, such as the International HapMap project, enable large-scale studies, such as genome-wide association st- ies, which could potentially identify most common genetic variants as well as rare variants of the human DNA that may alter individual’s susceptibility to disease and the response to medical treatment. Meanwhile the multi-electrode recording from behaving animals makes it feasible to control the animal mental activity, which could potentially lead to the development of useful brain–machine interfaces. - bracing the sheer volume of genetic, genomic, and other type of data, an essential approach is, ?rst of all, to avoid drowning the true signal in the data. It has been witnessed that theoretical approach to biology has emerged as a powerful and st- ulating research paradigm in biological studies, which in turn leads to a new - search paradigm in mathematics, physics, and computer science and moves forward with the interplays among experimental studies and outcomes, simulation studies, and theoretical investigations.
Catalyzing Inquiry at the Interface of Computing and Biology
Author: National Research Council
Publisher: National Academies Press
Published: 2006-01-01
Total Pages: 469
ISBN-13: 030909612X
DOWNLOAD EBOOKAdvances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Systemic Approaches in Bioinformatics and Computational Systems Biology
Author: Paola Lecca
Publisher:
Published: 2012
Total Pages: 0
ISBN-13: 9781613504352
DOWNLOAD EBOOK"This book presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data, covering three subject areas: bioinformatics, computational biology, and computational systems biology"--
