Bone Morphogenetic Proteins: From Local to Systemic Therapeutics

Bone Morphogenetic Proteins: From Local to Systemic Therapeutics

Author: Slobodan Vukicevic

Publisher: Springer Science & Business Media

Published: 2008-08-15

Total Pages: 349

ISBN-13: 3764385529

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Completing the PIR series, this volume summarizes the major advances made in the local and systemic use of bone morphogenetic proteins (BMPs). Chapters are dedicated to the regulation of BMP-signaling pathways; biological actions of BMPs in bone, cartilage, and teeth; clinical applications; and the potential systemic use of BMPs for tissues beyond bone. The authors are all recognized experts in the field of tissue engineering and regeneration.


Bone Morphogenetic Proteins: Systems Biology Regulators

Bone Morphogenetic Proteins: Systems Biology Regulators

Author: Slobodan Vukicevic

Publisher: Springer

Published: 2018-08-07

Total Pages: 0

ISBN-13: 9783319837536

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This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.


Bone Morphogenetic Proteins: Systems Biology Regulators

Bone Morphogenetic Proteins: Systems Biology Regulators

Author: Slobodan Vukicevic

Publisher: Springer

Published: 2017-03-14

Total Pages: 448

ISBN-13: 331947507X

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This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.


Biochemistry and Molecular Biology Compendium

Biochemistry and Molecular Biology Compendium

Author: Roger L. Lundblad

Publisher: CRC Press

Published: 2019-11-11

Total Pages: 427

ISBN-13: 1351680544

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This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers


Bioinformatics

Bioinformatics

Author: Information Resources Management Association

Publisher: IGI Global

Published: 2013-03-31

Total Pages: 1826

ISBN-13: 146663605X

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"Bioinformatics: Concepts, Methodologies, Tools, and Applications highlights the area of bioinformatics and its impact over the medical community with its innovations that change how we recognize and care for illnesses"--Provided by publisher.


Peterson's Principles of Oral and Maxillofacial Surgery

Peterson's Principles of Oral and Maxillofacial Surgery

Author: Larry J. Peterson

Publisher: PMPH-USA

Published: 2012

Total Pages: 1686

ISBN-13: 1607951118

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Peterson's Principles of Oral and Maxillofacial Surgery, Third Edition, encompasses a wide range of diverse topics making it a unique text amongst the medical and dental specialties. The purpose of this concise, easy-to-read two-volume text is to provide an authoritative and currently referenced survey of the specialty of Oral and Maxillofacial Surgery. It contains the necessary information for clinicians and is an ideal reference text for preparation for board certification in the specialty.


Encyclopedia of Inflammatory Diseases

Encyclopedia of Inflammatory Diseases

Author:

Publisher: Birkhäuser

Published: 2016-09-15

Total Pages: 0

ISBN-13: 9783764385309

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Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: Inflammatory Processes and Cells Inflammatory Diseases Mediators of Inflammation Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.


Analysis of Aggregates and Particles in Protein Pharmaceuticals

Analysis of Aggregates and Particles in Protein Pharmaceuticals

Author: Hanns-Christian Mahler

Publisher: John Wiley & Sons

Published: 2011-12-20

Total Pages: 480

ISBN-13: 1118150562

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This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.


Dental Implants, An Issue of Dental Clinics

Dental Implants, An Issue of Dental Clinics

Author: Ole Jensen

Publisher: Elsevier Health Sciences

Published: 2011-10-28

Total Pages: 281

ISBN-13: 1455749907

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Cutting edge information for all oral and maxillofacial surgeons on tissue engineering in maxillofacial reconstruction! Topics include innovations in implant design and treatment, esthetic considerations for implant therapy, bone graft augmentation-mandible, bone graft augmentation-maxilla, guided surgery for implant therapy, a practical approach to the use of zygomatic implants, all on four maxilla, orthognathics orthodontics and osseointegration, dental implants in cancer reconstruction, dental implants and the use of BMP-2, craniofacial implants, and much more!