The Mouse Nervous System
The Mouse Nervous System

Author: Charles Watson

Publisher: Academic Press

Published: 2011-11-28

Total Pages: 815

ISBN-13: 0123694973

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The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness

The Regulatory Genome
The Regulatory Genome

Author: Eric H. Davidson

Publisher: Elsevier

Published: 2010-07-19

Total Pages: 303

ISBN-13: 0080455573

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Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. - The only book in the market that is solely devoted to the genomic regulatory code for animal development - Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding - Presents a comprehensive treatment of molecular control elements that determine the function of genes - Provides a comparative treatment of development, based on principles rather than description of developmental processes - Considers the evolutionary processes in terms of the structural properties of gene regulatory networks - Includes 42 full-color descriptive figures and diagrams

Discovering the Human Connectome
Discovering the Human Connectome

Author: Olaf Sporns

Publisher: MIT Press

Published: 2012-08-31

Total Pages: 253

ISBN-13: 0262017903

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A pioneer in the field outlines new empirical and computational approaches to mapping the neural connections of the human brain. Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. In this book, Olaf Sporns surveys current efforts to chart these connections—to map the human connectome. He argues that the nascent field of connectomics has already begun to influence the way many neuroscientists collect, analyze, and think about their data. Moreover, the idea of mapping the connections of the human brain in their entirety has captured the imaginations of researchers across several disciplines including human cognition, brain and mental disorders, and complex systems and networks. Discovering the Human Connectome offers the first comprehensive overview of current empirical and computational approaches in this rapidly developing field.

The Neocortex
The Neocortex

Author: Wolf Singer

Publisher: MIT Press

Published: 2019-10-29

Total Pages: 449

ISBN-13: 0262043246

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Experts review the latest research on the neocortex and consider potential directions for future research. Over the past decade, technological advances have dramatically increased information on the structural and functional organization of the brain, especially the cerebral cortex. This explosion of data has radically expanded our ability to characterize neural circuits and intervene at increasingly higher resolutions, but it is unclear how this has informed our understanding of underlying mechanisms and processes. In search of a conceptual framework to guide future research, leading researchers address in this volume the evolution and ontogenetic development of cortical structures, the cortical connectome, and functional properties of neuronal circuits and populations. They explore what constitutes “uniquely human” mental capacities and whether neural solutions and computations can be shared across species or repurposed for potentially uniquely human capacities. Contributors Danielle S. Bassett, Randy M. Bruno, Elizabeth A. Buffalo, Michael E. Coulter, Hermann Cuntz, Stanislas Dehaene, James J. DiCarlo, Pascal Fries, Karl J. Friston, Asif A. Ghazanfar, Anne-Lise Giraud, Joshua I. Gold, Scott T. Grafton, Jennifer M. Groh, Elizabeth A. Grove, Saskia Haegens, Kenneth D. Harris, Kristen M. Harris, Nicholas G. Hatsopoulos, Tarik F. Haydar, Takao K. Hensch, Wieland B. Huttner, Matthias Kaschube, Gilles Laurent, David A. Leopold, Johannes Leugering, Belen Lorente-Galdos, Jason N. MacLean, David A. McCormick, Lucia Melloni, Anish Mitra, Zoltán Molnár, Sydney K. Muchnik, Pascal Nieters, Marcel Oberlaender, Bijan Pesaran, Christopher I. Petkov, Gordon Pipa, David Poeppel, Marcus E. Raichle, Pasko Rakic, John H. Reynolds, Ryan V. Raut, John L. Rubenstein, Andrew B. Schwartz, Terrence J. Sejnowski, Nenad Sestan, Debra L. Silver, Wolf Singer, Peter L. Strick, Michael P. Stryker, Mriganka Sur, Mary Elizabeth Sutherland, Maria Antonietta Tosches, William A. Tyler, Martin Vinck, Christopher A. Walsh, Perry Zurn

Regulation of Gene Expression by Small RNAs
Regulation of Gene Expression by Small RNAs

Author: Rajesh K. Gaur

Publisher: CRC Press

Published: 2009-04-27

Total Pages: 440

ISBN-13: 1420008706

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New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p

Plant Systems Biology
Plant Systems Biology

Author: Sacha Baginsky

Publisher: Springer Science & Business Media

Published: 2007-06-25

Total Pages: 362

ISBN-13: 376437439X

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This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.

Normal Table of Xenopus Laevis (Daudin)
Normal Table of Xenopus Laevis (Daudin)

Author: Pieter D. Nieuwkoop

Publisher: Garland Science

Published: 1994

Total Pages: 252

ISBN-13: 9780815318965

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A Systematical and Chronological Survey of the Development from the Fertilized Egg till the End of Metomorphosis

Transcriptome and Single-Cell Sequencing Analyses to Classify Immune Subtypes, Uncover Novel Biomarkers, and Assess Immunotherapeutic Responses in Cancer
Transcriptome and Single-Cell Sequencing Analyses to Classify Immune Subtypes, Uncover Novel Biomarkers, and Assess Immunotherapeutic Responses in Cancer

Author: Hongda Liu

Publisher: Frontiers Media SA

Published: 2024-07-24

Total Pages: 242

ISBN-13: 2832552064

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According to the most recent projections of the International Agency for Research on Cancer (IARC), there would be around 19.3 million new cases of cancer and 10 million cancer-related deaths globally in 2022. Cancer research has never halted. In particular, research into the cancer immunological microenvironment is gaining popularity.

Intelligent Computing Theories and Application
Intelligent Computing Theories and Application

Author: De-Shuang Huang

Publisher: Springer

Published: 2016-07-11

Total Pages: 882

ISBN-13: 331942291X

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This two-volume set LNCS 9771 and LNCS 9772 constitutes - in conjunction with the volume LNAI 9773 - the refereed proceedings of the 12th International Conference on Intelligent Computing, ICIC 2016, held in Lanzhou, China, in August 2016. The 221 full papers and 15 short papers of the three proceedings volumes were carefully reviewed and selected from 639 submissions. The papers are organized in topical sections such as signal processing and image processing; information security, knowledge discovery, and data mining; systems biology and intelligent computing in computational biology; intelligent computing in scheduling; information security; advances in swarm intelligence: algorithms and applications; machine learning and data analysis for medical and engineering applications; evolutionary computation and learning; independent component analysis; compressed sensing, sparse coding; social computing; neural networks; nature inspired computing and optimization; genetic algorithms; signal processing; pattern recognition; biometrics recognition; image processing; information security; virtual reality and human-computer interaction; healthcare informatics theory and methods; artificial bee colony algorithms; differential evolution; memetic algorithms; swarm intelligence and optimization; soft computing; protein structure and function prediction; advances in swarm intelligence: algorithms and applications; optimization, neural network, and signal processing; biomedical informatics and image processing; machine learning; knowledge discovery and natural language processing; nature inspired computing and optimization; intelligent control and automation; intelligent data analysis and prediction; computer vision; knowledge representation and expert system; bioinformatics.