The Pharmacist's Guide to Evidence-Based Medicine for Clinical Decision Making

The Pharmacist's Guide to Evidence-Based Medicine for Clinical Decision Making

Author: Patrick J. Bryant

Publisher: ASHP

Published: 2008-08-31

Total Pages: 209

ISBN-13: 1585282707

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Take the Practical Approach to Applying EBM Principles Pharmacists who make clinical decisions based on experience alone overestimate the efficacy and underestimate the safety risks of drugs. This leads to variations in services and treatment that result in inappropriate care, lack of care, and increased healthcare costs. Evidence-based medicine (EBM) employs the scientific method as the key source of knowledge for making clinical decisions. This easy-to-use new guide provides a practical approach for confidently applying EBM principles in daily practice. It's a straightforward process that allows pharmacists to incorporate their own clinical judgment while they make firm decisions and recommendations based on results of rigorously conducted clinical trials. Based on a five-step process perfected over 10 years at the University of Missouri, Kansas City, School of Pharmacy, this exciting new method makes it easy to apply the EBM approach in clinical settings. The new process streamlines the highly technical and complex original EBM method, greatly reducing its complexity while maintaining rigor. Categorizing quality of the evidence in a simple and logical manner, it provides critical, time-sensitive support for clinical decision-making.


The Pharmacy & Therapeutics Committee Evidence-Based Decision-Making Handbook

The Pharmacy & Therapeutics Committee Evidence-Based Decision-Making Handbook

Author: Delfini Delfini Group

Publisher: CreateSpace

Published: 2015-04-17

Total Pages: 150

ISBN-13: 9781511780773

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"Best help with evidence-based medicine available."Martin Gabica MD, Chief Medical Officer, Healthwise" "The guidelines and tools that you provided have been invaluable and are used on an almost daily basis as I review journal articles..." Maribeth M. Bettarelli, PharmD "The Delfini Group provided a comprehensive-and practical-approach to interpreting EBM, but most importantly, they provided a tool that I was able to easily incorporate into my practice..."Chris McFarland, PharmD Sound medical decisions require sound medical evidence. However, did you know that many estimate that the majority of published medical research studies are not reliable or are of uncertain reliability? You need an evidence-based process for quality patient care and to avoid waste. An evidence-based approach requires that evidence be evaluated for reliability and clinical usefulness. This book can help you. 1. How do you hire and evaluate an evidence-based staff if you lack evidence-based skills yourself? 2. What are some helpful resources and tips to save time? 3. Creating high quality monographs: How do you get the right information to the committee without swamping them with unnecessary details? 4. How do you keep your committee discussions evidence-based if your members lack these skills? 5. How do you make decisions on factors other than evidence? 6. How do you avoid typical pitfalls? Delfini medical evidologists and information scientists, Sheri Ann Strite and Michael E. Stuart MD, answer these questions and more. The authors have worked extensively with Pharmacy & Therapeutic groups around the country to help them establish and operate a truly evidence-based committee. Benefit from their experience and tips for evidence-based practice and efficiencies. Note: Contents are similar to our medical technology assessment book, but targeted for a Pharmacy & Therapeutics audience.


Oxford Handbook of Clinical Pharmacy

Oxford Handbook of Clinical Pharmacy

Author: Philip Wiffen

Publisher: OUP Oxford

Published: 2012-01-26

Total Pages: 544

ISBN-13: 0191629855

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Now fully updated for a second edition, the Oxford Handbook of Clinical Pharmacy remains the indispensible guide to clinical pharmacy, providing all the information needed for practising and student pharmacists. Presenting handy practical guidance in a quick-reference, bullet-point format, it will supply the knowledge and confidence you need to provide a clinical pharmacy service. The handbook includes information on controlled drugs, adverse drug reactions, interactions, communication skills, and confidentiality. It also features chapters on adherence, anaphylaxis, clinical trials, herbal medicines, patient management, pharmaceutical calculations, research, policy, and therapy related issues. Palliative care sections have been expanded to include symptom management and end-of-life pathways. Other new sections such as pharmacogenetics, thyroid disorders, and domiciliary oxygen therapy have been included. Complementing the current British National Formulary guidelines, the handbook gives prescribing points and linked concepts of relevance to clinical pharmacists. The content is evidence-based and contains a wealth of information from the authors' many years of clinical pharmacy experience.


The SAGE Handbook of Healthcare

The SAGE Handbook of Healthcare

Author: Decision Resources Inc

Publisher: SAGE

Published: 2008-05-22

Total Pages: 754

ISBN-13: 1847877001

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With escalating healthcare costs, changes to the regulatory control on pharmaceutical industries and the inevitable adjustments made in policies and investment in healthcare there is enormous interest in the commercial as well as the scientific aspects of today′s healthcare industry. The SAGE Handbook of Healthcare provides an authoritative analysis of the current (and anticipated) developments in the global healthcare industries. Providing a unique perspective that interfaces between the science and business aspects, it combines information on the latest scientific developments with applied, commercial business data from the global marketplace. The Handbook focuses on the aspects of paramount importance in the healthcare sector: - Pharmacoeconomics - Pharmacogenomics - Therapeutics - Diagnostics Areas covered include: - The role of nanotechnology, genomics and cell therapy in medicine - Diagnostics; Biomarkers and technological advances - Case studies in oncology and cardiovascular and CNS therapeutics


Handbook of Pharmaceutical Public Policy

Handbook of Pharmaceutical Public Policy

Author: Thomas Fulda

Publisher: CRC Press

Published: 2007-07-25

Total Pages: 714

ISBN-13: 9781439804261

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Get an invaluable view of the impact of economics and politics on pharmaceuticals in the United States Pharmacy and pharmaceutical drug use are highly regulated and the various regulatory forces interact with diverse goals. Pharmaceutical Public Policy is a comprehensive review of the legislation, trends, business developments, and policy interpretations that have shaped drug use during the last 50 years. This unique single source explains drug regulatory activity, the major insurance and payment systems, and the impact of economics and politics on drug use in the United States. Leading experts provide a thorough and objective look at public policy issues, making this text perfect for upper level undergraduate and graduate level pharmacy, medical, and public health educators and students. Pharmacists and pharmacy students must learn more than just the physical sciences and clinical aspects of the pharmaceutical industry. The rationale for policies, rules, and regulations is integral to understanding how to best serve patients and make the entire pharmaceutical sector more equitable and cost-effective. Pharmaceutical Public Policy examines the most pressing issues facing the industry, including control of the rising costs for drugs and ensuring correct drug usage by patients. This insightful text offers an in depth perspective of the policies and the debates that surround them. Chapters are well-referenced and many include helpful figures and tables to illustrate facts and ideas. Topics in Pharmaceutical Public Policy include: pharmacy law and regulation Medicare and prescription drug coverage FDA drug approval process Medicaid and prescription drugs public health pharmacy Department of Veterans Affairs pharmacy programs Department of Defense pharmacy programs innovative state drug program practices state and federal regulation of pharmacy the future of the pharmaceutical industry managed care pharmacy PBM’s (pharmacy benefit managers) risk minimization importation and reimportation biotechnology and pharmacogenetics policy and issues product promotion competition between drugs drug insurance design patient compliance abuse of prescription drugs health care systems and insurance in Europe much more Pharmaceutical Public Policy is a one-of-a-kind resource that explains just who the players are and the complexity of the issues that are examined in most pharmaceutical policy debates, and is perfect for pharmacy students, educators, other health professionals, trade association leaders, and policymakers.


Pharmacogenomics

Pharmacogenomics

Author: Mark A. Rothstein

Publisher: John Wiley & Sons

Published: 2003-04-09

Total Pages: 383

ISBN-13: 0471461202

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Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care. The three sections of this book, Research Issues, Clinical Issues, and Social Perspectives address key elements integral to a comprehensive discussion of this emerging field. This groundbreaking text... Examines new research strategies, methodologies, and ethical and social considerations of pharmacogenomics Addresses practical considerations of anticipated changes in education, training, oversight, guidelines and protocols, and continuing education requirements Provides analyses of the potential enormous impact of pharmacogenomics, such as in the standard of care and treatment, including perspectives from the fields of anthropology, law, ethics, and economics


Clinical Pharmacy and Therapeutics E-Book

Clinical Pharmacy and Therapeutics E-Book

Author: Roger Walker

Publisher: Elsevier Health Sciences

Published: 2011-10-24

Total Pages: 998

ISBN-13: 0702048488

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Now in its fifth edition, this best-selling, multidisciplinary textbook continues to draw on the skills of pharmacists and clinicians to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of pathophysiological processes, clinical pharmacy and the evidence base. New to this edition: Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors. Features: Key points boxes at the beginning of every chapter Case study tests at the end of every chapter Chapters co-authored by pharmacists and clinicians Organised by body system Consistent, clearly signposted chapter layout ‘...a unique and valuable support for all those involved or interested in drug therapy. This is a textbook that no university or pharmacy department, particularly those with employees studying at any level, and no pharmacist trying to develop their knowledge base should be without." Dr Chris Green and John Sexton, The Pharmaceutical Journal Now in its fifth edition, this best-selling, multidisciplinary textbook continues to draw on the skills of pharmacists and clinicians to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of pathophysiological processes, clinical pharmacy and the evidence base. New to this edition: Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors. Features: Key points boxes at the beginning of every chapter Case study tests at the end of every chapter Chapters co-authored by pharmacists and clinicians Organised by body system Consistent, clearly signposted chapter layout ‘...a unique and valuable support for all those involved or interested in drug therapy. This is a textbook that no university or pharmacy department, particularly those with employees studying at any level, and no pharmacist trying to develop their knowledge base should be without." Dr Chris Green and John Sexton, The Pharmaceutical Journal Stronger emphasis on understanding both the prescribing process and the clinical pharmacy process. All chapters completely revised and updated. Thirty-eight leading new authors.


Clinical Pharmacy and Therapeutics E-Book

Clinical Pharmacy and Therapeutics E-Book

Author: Cate Whittlesea

Publisher: Elsevier Health Sciences

Published: 2018-09-11

Total Pages: 1112

ISBN-13: 0702070106

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'This new edition of Clinical Pharmacy and Therapeutics was really very helpful when I was doing an MSc course in Advancing Pharmacy Practice and it was really very helpful in all the clinical diseases I have to read for my PBL. I also used it as one of my most reliable reference books for the in-course simulation ward rounds and other clinical case studies. It is a great book to have as a practising clinical or hospital pharmacist or even community pharmacist. It will also be of great use to anyone doing a course in pharmacotherapy. This book will always be of use to you throughout your studentship or when practising after graduation. It is also more portable than most other pharmacotherapy textbooks with the same amount of information.' Now in its sixth edition, this best-selling, multi-disciplinary textbook continues to draw on the skills of pharmacists, clinicians and nurses to present optimal drug regimens. The authors integrate an understanding of the disease processes with an appreciation of the pathophysiological processes, clinical pharmacy and the evidence base. Each chapter is co-written by a pharmacist and a clinician, and each chapter begins with key points and ends with cases to test understanding. The sixth edition is now on StudentConsult for the first time, giving online access to the full text. - Key points boxes at the beginning of each chapter - Case-study boxes throughout the chapters - Each chapter co-written by a pharmacist and a clinician - In-depth treatment of therapeutics to support pharmaceutical prescribing - Logical order and format: key points, epidemiology, aetiology, disease, clinical manifestations, investigations and treatment, drugs used in treatment. - Dosage reference sources given where appropriate, along with useful websites and further reading for each chapter. - New co-editor, Karen Hodson - Over 10 new authors - Now in 4-colour - On StudentConsult for the first time - New chapter on Dementia - Many new and revised illustrations - Chapters revised to include advances in therapeutics and changes to dose regimens and licensed indications - Updated case studies


Registries for Evaluating Patient Outcomes

Registries for Evaluating Patient Outcomes

Author: Agency for Healthcare Research and Quality/AHRQ

Publisher: Government Printing Office

Published: 2014-04-01

Total Pages: 385

ISBN-13: 1587634333

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This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.


Decision Making in a World of Comparative Effectiveness Research

Decision Making in a World of Comparative Effectiveness Research

Author: Howard G. Birnbaum

Publisher: Springer

Published: 2017-05-05

Total Pages: 289

ISBN-13: 9811032629

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In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of this burgeoning literature has focused on research findings, data and methods, Howard Birnbaum and Paul Greenberg (both of Analysis Group) have edited a book that provides a practical guide to decision making using the results of analysis and interpretation of CER. Decision Making in a World of Comparative Effectiveness contains chapters by senior industry executives, key opinion leaders, accomplished researchers, and leading attorneys involved in resolving disputes in the life sciences industry. The book is aimed at 'users' and 'decision makers' involved in the life sciences industry rather than those doing the actual research. This book appeals to those who commission CER within the life sciences industry (pharmaceutical, biologic, and device manufacturers), government (both public and private payers), as well as decision makers of all levels, both in the US and globally.