The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives
The Chemistry, Biology and Medical Applications of Hyaluronan and Its Derivatives

Author: T. C. Laurent

Publisher: Portland Press, London

Published: 1998

Total Pages: 368

ISBN-13:

DOWNLOAD EBOOK

The aim of this book is to collect within one volume information on hyaluronan. This polysaccharide has received rapid attention for two reasons: it has important regulative functions within cell biology; and it has become a commercially important product because of its use in ophthalmic surgery and treatment of joint diease. A number of other practical applications are also discussed. The book covers various aspects of hyaluronan from the structure and chemistry of the polymer to its metabolism, cell biological interactions, behaviour in pathological processes, and potentially new medical applications.

Carbohydrate Chemistry, Biology and Medical Applications
Carbohydrate Chemistry, Biology and Medical Applications

Author: Hari G. Garg

Publisher: Elsevier

Published: 2011-09-06

Total Pages: 431

ISBN-13: 0080558143

DOWNLOAD EBOOK

The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in Carbohydrate Chemistry, Biology and Medical Applications present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research. - Explains how carbohydrates are important to life - Details the chemistry, biology and medical aspects of carbohydrates - Interdisciplinary and international team of authors

Chemistry and Biology of Hyaluronan
Chemistry and Biology of Hyaluronan

Author: Hari G. Garg

Publisher: Elsevier

Published: 2004-07-14

Total Pages: 625

ISBN-13: 0080472222

DOWNLOAD EBOOK

It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. - Comprehensive look at the chemistry and biology of hyaluronans - Essential to Chemists, Biochemists and Medical researchers - Broad yet detailed review of this rapidly growing research area

Hyaluronan
Hyaluronan

Author: J F Kennedy

Publisher: Elsevier

Published: 2002-10-04

Total Pages: 1138

ISBN-13: 1845693124

DOWNLOAD EBOOK

Hyaluronan and its derivatives has developed very quickly in the last few years from a scientific novelty into an important new material for a diverse range of medical and biomaterial applications. This landmark conference focused on developments and applications in the use of hyaluronan in tissue repair and reconstruction, drug delivery systems, anti-cancer treatments and joint recovery and engineering.The entire range of hyaluronan progress is covered in depth by the more than 135 individual papers:Analytical chemistryStructural elucidation and basic chemistryElectron microscopy and atomic force microscopyProduction, purification and characterisationQuality in production systemsChemical modificationDerivatives and propertiesCross-linkingFree radical modificationPhysical characterisationRheologyAggregation phenomenaInteraction with water and solution propertiesCell biologyControl and regulation of HA synthasesCell surface chemistryHA cell receptors and cell signallingInteraction with proteins and other biological ligandsBiophysical aspectsEffects on pain receptorsNeurobiologyRole in organisation of extracellular matrixRole in development (embryogenesis): cell movement/migrationMedical applicationsUses in cartilage and wound repairInflammationWound regenerative healingSurgery and tissue engineeringViscosupplementation / osteoarthritisViscoaugmentation and viscoprotectionAnti-adhesion applicationsBrug delivery systemsBinding onto tumour cells and metastases - Outlines the proceedings of the landmark conference which focused on key developments and applications in the use of hyaluronan in tissue repair and reconstruction, among other uses - The entire range of hyaluronan processes is dealt with in depth by more than 135 individual papers presented in two volumes - Covers analytical chemistry, chemical modification, physical characterisation, cell biology and medical applications

The New Angiotherapy
The New Angiotherapy

Author: Tai-Ping D. Fan

Publisher: Springer Science & Business Media

Published: 2001-09-21

Total Pages: 618

ISBN-13: 1592591264

DOWNLOAD EBOOK

An international team of experts critically review the recent progress in basic and applied research in angiogenesis. Their cutting-edge discussion ranges from the stimulation and repression of angiogenesis to the discovery of novel targets and the use angiotherapy in the clinic. They also detail the fundamental concepts in the physiology and pathophysiology of angiogenesis and evaluate the potential of angiotherapy in the management of angiogenic disease, highlighting some of the angiogenics and antiangiogenics both in development and in clinical trials.

Cosmeceuticals
Cosmeceuticals

Author: Peter Elsner

Publisher: CRC Press

Published: 2000-06-09

Total Pages: 385

ISBN-13: 0824742397

DOWNLOAD EBOOK

This text defines what constitutes cosmeceuticals and discusses various classes of products, from anti-ageing skin care and repair, anti-acne, and hair-growth compounds to agents for treating skin infections, rashes and irritations.

Practical Aspects of Hyaluronan Based Medical Products
Practical Aspects of Hyaluronan Based Medical Products

Author: J.W. Kuo

Publisher: CRC Press

Published: 2005-09-23

Total Pages: 238

ISBN-13: 1420037641

DOWNLOAD EBOOK

The ballooning body of research devoted to hyaluronan (HA) reflects its enormous potential for various medical applications. There have been many successes of varying degrees in the development of medical products based on HA, but also some setbacks. While there is obviously ample information available on the chemistry and various properties of thi

Advances in Carbohydrate Chemistry and Biochemistry
Advances in Carbohydrate Chemistry and Biochemistry

Author:

Publisher: Academic Press

Published: 2017-11-23

Total Pages: 288

ISBN-13: 0128121807

DOWNLOAD EBOOK

Advances in Carbohydrate Chemistry and Biochemistry, Volume 74, presents a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. Since its inception in 1945, the series has provided critical and informative articles written by research specialists that integrate the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology to the study of carbohydrates. - Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research - Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates - Informs and updates on all the latest developments in the field

Biomaterials for Tissue Engineering Applications
Biomaterials for Tissue Engineering Applications

Author: Jason A. Burdick

Publisher: Springer Science & Business Media

Published: 2010-12-07

Total Pages: 562

ISBN-13: 3709103851

DOWNLOAD EBOOK

A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: (i) general materials technology (e.g., fibrous tissue scaffolds) and (ii) applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field.

Natural-Based Polymers for Biomedical Applications
Natural-Based Polymers for Biomedical Applications

Author: Rui L. Reis

Publisher: Elsevier

Published: 2008-08-15

Total Pages: 829

ISBN-13: 1845694813

DOWNLOAD EBOOK

Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering.The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility.Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. - Examines the sources, processing and properties of natural based polymers for biomedical applications - Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality - Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine