Surgery for Gastric Cancer
Surgery for Gastric Cancer

Author: Sung Hoon Noh

Publisher: Springer

Published: 2019-05-27

Total Pages: 356

ISBN-13: 3662455838

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This book clearly describes the surgical procedures employed in patients with gastric cancer. The techniques used in the various types of gastrectomy are presented step by step, and the roles of endoscopic treatment and chemotherapy are also discussed. A distinctive practical feature is the provision of accompanying online videos of standard surgical procedures, which will serve as excellent learning aids for novice practitioners and provide ideal teaching material for experienced surgeons. Surgery remains the mainstay in the treatment of gastric cancer. With advances in tumor biology and technical developments, gastric cancer surgery has become more diverse and its outcomes have steadily improved. However, further improvement of certain aspects of surgical procedures and techniques is still required. Surgery for Gastric Cancer will acquaint readers with the state of the art in the field and prove a valuable tool in the quest for optimal practice.

Staging Laparoscopy
Staging Laparoscopy

Author: P. Hohenberger

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 206

ISBN-13: 3642562906

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Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

The Biology of Gastric Cancers
The Biology of Gastric Cancers

Author: Timothy Wang

Publisher: Springer Science & Business Media

Published: 2009-02-25

Total Pages: 654

ISBN-13: 0387691820

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As someone who has spent nearly half his life wondering about the relationship between Helicobacter and gastric cancer, I find this textbook on the subject exciting and timely. In fact, I am not aware of any other volume that has been able to distil so much new knowledge into such a comprehensive account of a poorly understood field. Taking my own view, as a scientist placed in the middle of the spectrum between basic science and clinical medicine, I can see that the editors, Jim Fox, Andy Giraud, and Timothy Wang, provide a broad mix of expertise, which ensures that the subject is treated with the right balance. From clinicopathologic observations in humans, to epidemiology, through animal models, to molecular and cell biology, this team has hit the mark for most readers. Fox is a well-known leader in animal models with broad expertise. He pioneered the field with observations on Helicobacter species in animals, from the time when only one spiral gastric bac- rium was known, “Campylobacter pyloridis. ” Fox partners with Wang, whose team recently announced a dramatic advance in the field of carcinogenesis—the obser- tion that bone marrow–derived stem cells participate in the changes that become cancer. To this nice mix has been added Andy Giraud from my own country, who brings to the table some remarkable genetic models of gastric cancer based on alterations in the gp130/stat3-signaling pathway.

Management of Gastric Cancer
Management of Gastric Cancer

Author: Paul H. Sugarbaker

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 405

ISBN-13: 1461538823

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Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Gastric Cancer
Gastric Cancer

Author: Vivian E. Strong

Publisher: Springer

Published: 2015-06-10

Total Pages: 331

ISBN-13: 3319158260

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This volume provides the most comprehensive and complete resource available on all aspects of gastric cancer and it’s management. The book covers topics such as oncologic approaches to staging, treating, and following patients, filling a critical need for resource materials on these areas. As multidisciplinary care is an integral part of gastric cancer treatment, this text is unique in including a renowned group of expert authors from a variety of disciplines, including pathology, gastroenterology, medical oncology, surgery and clinical genetics. In addition, authors from an international pool of gastric cancer experts have covered the breadth of practice and understanding globally. Edited and organized by an expert from one of the most highly respected cancer institutions in the country, Gastric Cancer: Principles and Practice is an expert review of this field, serving as a valuable reference for physicians in training and in practice, as well as for researchers who are interested in the scope of issues and advances in this important malignancy.

Perioperative Chemotherapy
Perioperative Chemotherapy

Author: U. Metzger

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 170

ISBN-13: 3642824323

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One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

Theranostics Approaches to Gastric and Colon Cancer
Theranostics Approaches to Gastric and Colon Cancer

Author: Ganji Seeta Rama Raju

Publisher: Springer Nature

Published: 2020-03-04

Total Pages: 261

ISBN-13: 9811520178

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This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Morson and Dawson's Gastrointestinal Pathology
Morson and Dawson's Gastrointestinal Pathology

Author: David W. Day

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 704

ISBN-13: 047075530X

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Morson and Dawson's Gastrointestinal Pathology is one of the 'Gold Standards' of pathology textbooks. It has been completely revised to incorporate the latest advances in this rapidly evolving field including the developments in gastric cancer and Helicobacter pylori and the revised classification of other common gastrointestinal conditions. This new edition features a wealth of new material presented in full colour for the first time.

Gastric Cancer: the 25-year R-Evolution
Gastric Cancer: the 25-year R-Evolution

Author: Giovanni de Manzoni

Publisher: Springer Nature

Published: 2021-10-15

Total Pages: 276

ISBN-13: 3030731588

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Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.

Geriatric Gastroenterology
Geriatric Gastroenterology

Author: C. S. Pitchumoni

Publisher: Springer Science & Business Media

Published: 2012-07-26

Total Pages: 660

ISBN-13: 1441916237

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As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.