The American Phage Group
The American Phage Group

Author: William C. Summers

Publisher: Yale University Press

Published: 2023-01-10

Total Pages: 313

ISBN-13: 0300263562

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A fascinating historical account of the American Phage Group and how its new research framework became the foundation for molecular biology This book is the first critical and analytical study of the American Phage Group--a small group of scientists who gathered around Max Delbrück, Salvador Luria, and Alfred Hershey between 1940 and 1960--and how this novel research program became the foundation of the field of molecular biology. These three young, charismatic, and iconoclastic scientists were convinced of the importance of bacterial viruses (bacteriophages) to the study of the gene and of heredity in general. Based on substantial archival research, numerous participant interviews collected over the past thirty years, and an intimate knowledge of the relevant scientific literature in the field, William C. Summers has written a fascinating new history of the American Phage Group. Rather than a linear narrative of progress by past heroes, this book emphasizes the diversity and historical contingencies in the group's development.

The American Phage Group
The American Phage Group

Author: William C. Summers

Publisher: Yale University Press

Published: 2023-01-10

Total Pages: 313

ISBN-13: 0300263562

DOWNLOAD EBOOK

A fascinating historical account of the American Phage Group and how its new research framework became the foundation for molecular biology This book is the first critical and analytical study of the American Phage Group--a small group of scientists who gathered around Max Delbrück, Salvador Luria, and Alfred Hershey between 1940 and 1960--and how this novel research program became the foundation of the field of molecular biology. These three young, charismatic, and iconoclastic scientists were convinced of the importance of bacterial viruses (bacteriophages) to the study of the gene and of heredity in general. Based on substantial archival research, numerous participant interviews collected over the past thirty years, and an intimate knowledge of the relevant scientific literature in the field, William C. Summers has written a fascinating new history of the American Phage Group. Rather than a linear narrative of progress by past heroes, this book emphasizes the diversity and historical contingencies in the group's development.

The Bacteriophages
The Bacteriophages

Author: Richard Calendar

Publisher: Oxford University Press

Published: 2006

Total Pages: 761

ISBN-13: 0195148509

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This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity.Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.

Bacteriophages
Bacteriophages

Author: Elizabeth Kutter

Publisher: CRC Press

Published: 2004-12-28

Total Pages: 666

ISBN-13: 1135511780

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In response to the emergence of pathogenic bacteria that cannot be treated with current antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight multidrug-resistant bacteria. Bacteriophages: Biology and Applications provides unparalleled, comprehensive information on bacteriophages and their applications, such as phage therapy. It offers techniques, media, and methodology involved in isolating and working with therapeutic phages. Photographs, line drawings, and electron micrographs of phages are also included. With its broad approach, this book is a useful reference for microbiologists, hematologists, and infectious disease researchers.

Understanding Viruses
Understanding Viruses

Author: Teri Shors

Publisher: Jones & Bartlett Publishers

Published: 2013

Total Pages: 732

ISBN-13: 0763785539

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The ideal text for undergraduate students majoring in biology, microbiology, medical technology, or pre-med, the Second Edition of Understanding Viruses provides a balanced approach to this fascinating discipline, combining the molecular, clinical, and historical aspects of virology. Updated throughout to keep pace with this fast-paced field, the text provides a strong, comprehensive introduction to human viral diseases. New material on molecular virology as well as new virus families presented coupled with chapters on viral diseases of animals; the history of clinical trials, gene therapy, and xenotranplantation; prions and viroids; plant viruses; and bacteriophages add to the scope of the text. Chapters discussing specific viral diseases weave in an epidemiological and global perspective and include treatment and prevention information. Contemporary case studies, Refresher Boxes, and Virus Files engage students in the learning process. With a wealth of student and instructor support tools, Understanding Viruses is an accessible, exciting, and engaging text for your virology course.

Nobel Laureates in Medicine or Physiology
Nobel Laureates in Medicine or Physiology

Author: Daniel M. Fox

Publisher: Routledge

Published: 2019-01-15

Total Pages: 655

ISBN-13: 0429665032

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Originally published in 1990, Nobel Laureates in Medicine or Physiology is a biographical reference work about the recipients of Nobel Prizes in Medicine or Physiology from 1901-1989. Each article is written by an accomplished historian of medicine or science. The book is designed to be accessible to students and general readers as well as to specialists in medical science and history. Each article combines personal and scientific biography, and each has an extensive biography to guide further reading and research.

A History of the Life Sciences, Revised and Expanded
A History of the Life Sciences, Revised and Expanded

Author: Lois N. Magner

Publisher: CRC Press

Published: 2002-08-13

Total Pages: 456

ISBN-13: 0824743601

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A clear and concise survey of the major themes and theories embedded in the history of life science, this book covers the development and significance of scientific methodologies, the relationship between science and society, and the diverse ideologies and current paradigms affecting the evolution and progression of biological studies. The author discusses cell theory, embryology, physiology, microbiology, evolution, genetics, and molecular biology; the Human Genome Project; and genomics and proteomics. Covering the philosophies of ancient civilizations to modern advances in genomics and molecular biology, the book is a unique and comprehensive resource.

Companion to the History of Modern Science
Companion to the History of Modern Science

Author: G N Cantor

Publisher: Routledge

Published: 2020-10-07

Total Pages: 754

ISBN-13: 1000158853

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The 67 chapters of this book describe and analyse the development of Western science from 1500 to the present day. Divided into two major sections - 'The Study of the History of Science' and 'Selected Writings in the History of Science' - the volume describes the methods and problems of research in the field and then applies these techniques to a wide range of fields. Areas covered include: * the Copernican Revolution * Genetics * Science and Imperialism * the History of Anthropology * Science and Religion * Magic and Science. The companion is an indispensable resource for students and professionals in History, Philosophy, Sociology and the Sciences as well as the History of Science. It will also appeal to the general reader interested in an introduction to the subject.

A Tale of Two Viruses
A Tale of Two Viruses

Author: Neeraja Sankaran

Publisher: University of Pittsburgh Press

Published: 2021-03-09

Total Pages: 410

ISBN-13: 0822987716

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In 1965, French microbiologist André Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny—one of the two types of viral life cycles—which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses—bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer—and the importance of Lwoff’s discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell’s genetic material indefinitely, or until induced by UV radiation. But until Lwoff’s discovery of the mechanism of lysogeny, microbiologist Félix d’Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices.