Artificial intelligence (AI) is taking an increasingly important role in our society. From cars, smartphones, airplanes, consumer applications, and even medical equipment, the impact of AI is changing the world around us. The ability of machines to demonstrate advanced cognitive skills in taking decisions, learn and perceive the environment, predict certain behavior, and process written or spoken languages, among other skills, makes this discipline of paramount importance in today's world. Although AI is changing the world for the better in many applications, it also comes with its challenges. This book encompasses many applications as well as new techniques, challenges, and opportunities in this fascinating area.
Here's the first focused book that puts the full range of cutting-edge biological text mining techniques and tools at your command. This comprehensive volume describes the methods of natural language processing (NLP) and their applications in the biological domain, and spells out in detail the various lexical, terminological, and ontological resources now at your disposal - and how best to utilize them.
This open access book describes the results of natural language processing and machine learning methods applied to clinical text from electronic patient records. It is divided into twelve chapters. Chapters 1-4 discuss the history and background of the original paper-based patient records, their purpose, and how they are written and structured. These initial chapters do not require any technical or medical background knowledge. The remaining eight chapters are more technical in nature and describe various medical classifications and terminologies such as ICD diagnosis codes, SNOMED CT, MeSH, UMLS, and ATC. Chapters 5-10 cover basic tools for natural language processing and information retrieval, and how to apply them to clinical text. The difference between rule-based and machine learning-based methods, as well as between supervised and unsupervised machine learning methods, are also explained. Next, ethical concerns regarding the use of sensitive patient records for research purposes are discussed, including methods for de-identifying electronic patient records and safely storing patient records. The book’s closing chapters present a number of applications in clinical text mining and summarise the lessons learned from the previous chapters. The book provides a comprehensive overview of technical issues arising in clinical text mining, and offers a valuable guide for advanced students in health informatics, computational linguistics, and information retrieval, and for researchers entering these fields.
Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.
Biomedical Natural Language Processing is a comprehensive tour through the classic and current work in the field. It discusses all subjects from both a rule-based and a machine learning approach, and also describes each subject from the perspective of both biological science and clinical medicine. The intended audience is readers who already have a background in natural language processing, but a clear introduction makes it accessible to readers from the fields of bioinformatics and computational biology, as well. The book is suitable as a reference, as well as a text for advanced courses in biomedical natural language processing and text mining.
This volume presents an extensive collection of contributions covering aspects of the exciting and important research field of data mining techniques in biomedicine. Coverage includes new approaches for the analysis of biomedical data; applications of data mining techniques to real-life problems in medical practice; comprehensive reviews of recent trends in the field. The book addresses incorporation of data mining in fundamental areas of biomedical research: genomics, proteomics, protein characterization, and neuroscience.
Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains.
Predictive Modeling in Biomedical Data Mining and Analysis presents major technical advancements and research findings in the field of machine learning in biomedical image and data analysis. The book examines recent technologies and studies in preclinical and clinical practice in computational intelligence. The authors present leading-edge research in the science of processing, analyzing and utilizing all aspects of advanced computational machine learning in biomedical image and data analysis. As the application of machine learning is spreading to a variety of biomedical problems, including automatic image segmentation, image classification, disease classification, fundamental biological processes, and treatments, this is an ideal reference. Machine Learning techniques are used as predictive models for many types of applications, including biomedical applications. These techniques have shown impressive results across a variety of domains in biomedical engineering research. Biology and medicine are data-rich disciplines, but the data are complex and often ill-understood, hence the need for new resources and information. - Includes predictive modeling algorithms for both Supervised Learning and Unsupervised Learning for medical diagnosis, data summarization and pattern identification - Offers complete coverage of predictive modeling in biomedical applications, including data visualization, information retrieval, data mining, image pre-processing and segmentation, mathematical models and deep neural networks - Provides readers with leading-edge coverage of biomedical data processing, including high dimension data, data reduction, clinical decision-making, deep machine learning in large data sets, multimodal, multi-task, and transfer learning, as well as machine learning with Internet of Biomedical Things applications
Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research.
