Understanding Pancreatic Cancer: Current Trends - ECAB

Understanding Pancreatic Cancer: Current Trends - ECAB

Author: Markus W Büchler

Publisher: Elsevier Health Sciences

Published: 2012-06-15

Total Pages: 140

ISBN-13: 8131232441

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Pancreatic cancer remains a dismal disease with an incidence that is on the rise even in a low incidence region like India. In recent years, there have been significant advances in the understanding of pancreatic cancer largely due to strides in modern molecular biology, pathology and radiology. While molecular biology continues to provide an optimistic vision for future treatment approaches to this deadly disease, the recent identification of PanIN’s and resection margins in pancreatic cancer have important implications for current day-to-day practice. This book explains how better understanding of IPMN and its management has improved the scope of pancreatic tumors. It also explains what role do heat shock proteins perform in cancer. The book gives concise description on how a number of important advances have made pancreatic pathology an exciting and rapidly advancing field. There are chapters that explain how good endoscopic ultrasound is in detection of cancer pancreas and also talk about experimental studies on obstructive jaundice and biliary drainage. Neo-adjuvant strategies in operable pancreatic adenocarcinomas are also being explained in detail. It is sincerely hoped that this book will update the busy clinician as well as the academician on various aspects of current importance in management of pancreatic cancer. Understanding the role of IPMN in improving the scope of pancreatic tumors Describing performance of heat shock proteins in cancer Throwing some light on usefulness of endoscopic ultrasound in detecting cancer pancreas Getting an insight into neo-adjuvant strategies in operable pancreatic adenocarcinomas


Pancreatic cancer

Pancreatic cancer

Author: Andrew M. Lowy

Publisher: Clinics: Surgery

Published: 2010

Total Pages: 0

ISBN-13: 9781437718799

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This issue of the Surgical Oncology Clinics will cover the following topics: imaging for pancreatic cancer, EUS staging and novel therapeutics for pancreatic cancer, management of cystic tumors, management of IPMN, laparoscopic surgery for pancreatic tumors, current concepts in the surgical management of pancreatic cancer, management of borderline resectable pancreatic cancer, regionalization of pancreatic surgery, update on adjuvant trials for pancreatic cancer, neoadjuvant therapy for pancreatic cancer, novel targets for pancreatic cancer therapy, and new frontiers in pancreatic cancer.


Contentious Issues in Surgical Gastroenterology - ECAB

Contentious Issues in Surgical Gastroenterology - ECAB

Author:

Publisher: Elsevier Health Sciences

Published: 2012-06-13

Total Pages: 121

ISBN-13: 813123245X

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All surgeons are convinced that they provide the best possible care to their patients and fortunately most patients are happy with their surgeons. Where safety and quality were once considered to be self-evident, these issues need to be made more explicit in modern surgery. Doctors and the general public alike are nowadays more aware of the variations in quality that exist among surgeons and institutions and of the unwarranted harmful effects surgery can have. Super- or sub-specialization seems one way to improve both its quality and safety. Surgical Gastroenterology or Gastrointestinal Surgery is one of these new superspecialties. The path towards this specialization is not easy and turf battles between General Surgery and Surgical Gastroenterology are still being fought. Professor Kaushik recounts the history and development of this superspecialty in India. He recounts that although the history of Surgical Gastroenterology in this country is short, its future is bright but, as has happened in other countries, its further division into organ-based superspecialties can be expected. ‘Practice makes one perfect’ is the motto that is probably true for the high-risk surgery which is still being performed in small institutions or by surgeons with only little expertise. The inverse correlation between volume and outcome expressed as mortality and morbidity has been shown all over the world. Wouters et al systematically analyze the literature covering this topic. They also show that concentration and regionalization do not automatically lead to an improved quality of surgery, since other issues for quality assurance are of equal importance, such as adherence to evidence-based guidelines, feedback, and monitoring. Despite all the inputs in training and instruction by experts, a uniformly high quality of surgery is hard to achieve in day-to-day gastrointestinal surgery. Sudhir Joseph and his colleagues show that a dedicated checklist can save lives and reduce postoperative morbidity in many countries with different systems and levels of healthcare. A similar beneficial effect was found in The Netherlands using a more comprehensive checklist that covers the whole period of the hospital stay. The new type of surgeon is aware of the principles of evidence-based medicine and he/she will challenge the dogmas of the ‘old’ surgery. Over the years our surgical masters have told us about the importance of good pre-operative and postoperative care for our patients. The bowel should be put at rest before operation and oral feeding restored only slowly after surgery starting with nothing by mouth to sips of clear water. Bed rest was essential for recovery. He introduced the ERAS (Enhanced Recovery after Surgery) strategy also named Fast Track Surgery. Mitchell et al provide ample evidence that all surgeons should adopt the ERAS strategy. Implementation of this will lead to better and more cost-effective operations.


Carcinoma of the Gallbladder: The Current Scenario - ECAB - E-Book

Carcinoma of the Gallbladder: The Current Scenario - ECAB - E-Book

Author:

Publisher: Elsevier Health Sciences

Published: 2015-06-03

Total Pages: 200

ISBN-13: 8131239993

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Carcinoma of the gallbladder is the most common cancers in North India which is very difficult to treat as well as manage as it is associated with many important issues. The current volume covers the topic right from its etiopathology to its palliation and gives an overview on the current knowledge of the disease. The international authorship of this book reflects the multidisciplinary nature of the book and of the field of gallbladder cancer care. The book promises to stimulate studies to provide specific answers to some unanswered questions. Above all it will destroy the myth that gallbladder carcinoma is incurable and will thus benefit a large number of patients. This edition focuses mainly on Etiopathogenesis of gallbladder cancer Management of gallbladder carcinoma Diagnosis and treatment outcomes Aggressive surgical management Molecular biology and pathogenesis of gallbladder cancer