Handbook of Statistical Genomics

Handbook of Statistical Genomics

Author: David J. Balding

Publisher: John Wiley & Sons

Published: 2019-07-09

Total Pages: 1740

ISBN-13: 1119429250

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A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.


Statistical Methods for Plant Variety Evaluation

Statistical Methods for Plant Variety Evaluation

Author: R.A. Kempton

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 203

ISBN-13: 9400915039

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The International Centre for Advanced Mediterranean Agronomic Studies (CIHEAM), established in 1962, is an intergovernmental organization of four teen countries: Albania, Algeria, Egypt, France, Greece, Italy, Lebanon, Malta, Morocco, Portugal, Spain, Tunisia, Turkey and Yugoslavia. Four institutes (Bari, Italy; Chania, Greece; Montpellier, France and Zaragoza, Spain) provide post-graduate education at the Master of Science level. CIHEAM promotes research networks on Mediterranean agricultural priorities, supports the organization of specialized education in member countries, holds seminars and workshops bringing together technologists and scientists involved in Mediterranean agriculture and regularly produces diverse publications including the series 'Options Mediterraneennes'. Through these activities, CIHEAM promotes North/South dialogue and international co-operation for agricultural development in the Mediterranean region. Plant breeding is, since 1982, one of the fields in which CIHEAM is con ducting a programme of training and promotion of research, through its Mediterranean Agronomic Institute of Zaragoza. The programme includes a one-year advanced specialization course, a series of two-week courses for professionals, and support for collaborative research activities in Mediterranean-relevant species. Many of these activities are organized in col laboration with national and international institutions. The publication in 1993 of Plant Breeding. Principles and Prospects, which ini tiated the Chapman & Hall's Plant Breeding Series, has become an important feature of CIHEAM's plant breeding programme. We are now pleased to add a further volume to that series: the present book, Statistical Methods for Plant Variety Evaluation.


GGE Biplot Analysis

GGE Biplot Analysis

Author: Weikai Yan

Publisher: CRC Press

Published: 2002-08-28

Total Pages: 287

ISBN-13: 1420040375

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Research data is expensive and precious, yet it is seldom fully utilized due to our ability of comprehension. Graphical display is desirable, if not absolutely necessary, for fully understanding large data sets with complex interconnectedness and interactions. The newly developed GGE biplot methodology is a superior approach to the graphical analys


Genetic Data Analysis for Plant and Animal Breeding

Genetic Data Analysis for Plant and Animal Breeding

Author: Fikret Isik

Publisher: Springer

Published: 2017-09-09

Total Pages: 409

ISBN-13: 3319551779

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This book fills the gap between textbooks of quantitative genetic theory, and software manuals that provide details on analytical methods but little context or perspective on which methods may be most appropriate for a particular application. Accordingly this book is composed of two sections. The first section (Chapters 1 to 8) covers topics of classical phenotypic data analysis for prediction of breeding values in animal and plant breeding programs. In the second section (Chapters 9 to 13) we provide the concept and overall review of available tools for using DNA markers for predictions of genetic merits in breeding populations. With advances in DNA sequencing technologies, genomic data, especially single nucleotide polymorphism (SNP) markers, have become available for animal and plant breeding programs in recent years. Analysis of DNA markers for prediction of genetic merit is a relatively new and active research area. The algorithms and software to implement these algorithms are changing rapidly. This section represents state-of-the-art knowledge on the tools and technologies available for genetic analysis of plants and animals. However, readers should be aware that the methods or statistical packages covered here may not be available or they might be out of date in a few years. Ultimately the book is intended for professional breeders interested in utilizing these tools and approaches in their breeding programs. Lastly, we anticipate the usage of this volume for advanced level graduate courses in agricultural and breeding courses.


Genotype X Environment Interactions

Genotype X Environment Interactions

Author: Paolo Annicchiarico

Publisher: Food & Agriculture Org.

Published: 2002

Total Pages: 136

ISBN-13: 9789251048702

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The projected increase in world population levels and the subsequent rise in food demand represents a huge challenge for agricultural production systems worldwide. This publication examines the opportunities and challenges raised by the use of plant genetic resources and highlights the contribution that data from multi-environment yield trials can provide for the definition of adaptation strategies and yield stability targets in plant breeding programmes. It contains a case study about a durum wheat crop programme in Algeria, and also includes a CD-ROM with data from IRRISTAT, a programme developed by the International Rice Research Institute (IRRI).


Selection Methods in Plant Breeding

Selection Methods in Plant Breeding

Author: Izak Bos

Publisher: Springer Science & Business Media

Published: 2007-10-26

Total Pages: 462

ISBN-13: 1402063709

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Written for plant breeders, researchers and post-graduate students, this excellent new book provides a comprehensive review of the methods and underlying theoretical foundations used for selection in plant breeding programs. The authors review basic elements of population and quantitative genetic theory, moving on to consider in a unique way the tackling of the problems presented by soil heterogeneity and intergenotypic competition when selecting quantitative characters.


Variance Components

Variance Components

Author: Shayle R. Searle

Publisher: John Wiley & Sons

Published: 2009-09-25

Total Pages: 537

ISBN-13: 0470317698

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WILEY-INTERSCIENCE PAPERBACK SERIES The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. ". . .Variance Components is an excellent book. It is organized and well written, and provides many references to a variety of topics. I recommend it to anyone with interest in linear models." —Journal of the American Statistical Association "This book provides a broad coverage of methods for estimating variance components which appeal to students and research workers . . . The authors make an outstanding contribution to teaching and research in the field of variance component estimation." —Mathematical Reviews "The authors have done an excellent job in collecting materials on a broad range of topics. Readers will indeed gain from using this book . . . I must say that the authors have done a commendable job in their scholarly presentation." —Technometrics This book focuses on summarizing the variability of statistical data known as the analysis of variance table. Penned in a readable style, it provides an up-to-date treatment of research in the area. The book begins with the history of analysis of variance and continues with discussions of balanced data, analysis of variance for unbalanced data, predictions of random variables, hierarchical models and Bayesian estimation, binary and discrete data, and the dispersion mean model.


Plant Breeding: Past, Present and Future

Plant Breeding: Past, Present and Future

Author: John E. Bradshaw

Publisher: Springer

Published: 2016-03-08

Total Pages: 710

ISBN-13: 3319232851

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This book aims to help plant breeders by reviewing past achievements, currently successful practices, and emerging methods and techniques. Theoretical considerations are also presented to strike the right balance between being as simple as possible but as complex as necessary. The United Nations predicts that the global human population will continue rising to 9.0 billion by 2050. World food production will need to increase between 70-100 per cent in just 40 years. First generation bio-fuels are also using crops and cropland to produce energy rather than food. In addition, land area used for agriculture may remain static or even decrease as a result of degradation and climate change, despite more land being theoretically available, unless crops can be bred which tolerate associated abiotic stresses. Lastly, it is unlikely that steps can be taken to mitigate all of the climate change predicted to occur by 2050, and beyond, and hence adaptation of farming systems and crop production will be required to reduce predicted negative effects on yields that will occur without crop adaptation. Substantial progress will therefore be required in bridging the yield gap between what is currently achieved per unit of land and what should be possible in future, with the best farming methods and best storage and transportation of food, given the availability of suitably adapted cultivars, including adaptation to climate change. My book is divided into four parts: Part I is an historical introduction; Part II deals with the origin of genetic variation by mutation and recombination of DNA; Part III explains how the mating system of a crop species determines the genetic structure of its landraces; Part IV considers the three complementary options for future progress: use of sexual reproduction in further conventional breeding, base broadening and introgression; mutation breeding; and genetically modified crops.