Regulation of Secondary Metabolism in Actinomycetes

Regulation of Secondary Metabolism in Actinomycetes

Author: Stuart Shapiro

Publisher: CRC Press

Published: 2020-10-28

Total Pages: 320

ISBN-13: 1000141993

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This book provides a comprehensive examination of biochemical and genetic regulatory phenomena as they relate to the activity of actinomycete secondary metabolic pathways and the functioning of secondary metabolites as endogenous effectors of cytodifferentiation. Approximately 50 illustrations accompany the text.


Actinomycetes

Actinomycetes

Author: Evi Stegmann

Publisher:

Published: 2020-09-04

Total Pages: 362

ISBN-13: 9783039369102

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Beyond being the most important natural compound source, actinomycetes are the origin of up to two-thirds of all clinically used antibiotics. Currently, new antimicrobials are urgently needed, as infections caused by antibiotic-resistant pathogens are on the rise. In the identification of new antibiotics, many scientists are currently investigating biosynthetic aspects of antibiotic production in actinomycetes. Since the emergence of next-generation sequencing technologies, the field of antibiotics research has experienced a remarkable revival. These bacteria have the potential to produce more antibiotics than previously thought possible. Some antibiotics are produced in standard media, while others require the presence of a specific signaling molecule in the medium. Others, however, are only produced when the native regulation of the biosynthesis gene cluster is overruled. This book covers topics in the field of antibiotic-producing actinomycetes. The following tops are addressed: - Approaches to access novel antibiotic producers for novel natural compounds - Omics and genome mining approaches for the discovery of novel natural compounds - Analyses and genetic engineering of antibiotic biosynthesis - Regulation of the secondary metabolism in actinomycetes


Secondary Metabolites

Secondary Metabolites

Author: Derek J. Chadwick

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 328

ISBN-13: 0470514353

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A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary metabolites as natural products having no obvious part to play in the producing organism's life cycle. Covers issues related to genetic and antibiotic applications.


Biology and Biotechnology of Actinobacteria

Biology and Biotechnology of Actinobacteria

Author: Joachim Wink

Publisher: Springer

Published: 2017-10-19

Total Pages: 398

ISBN-13: 3319603396

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This book provides in-depth insights into the biology, taxonomy, genetics, physiology and biotechnological applications of Actinobacteria. It especially focuses on the latter, reviewing the wide variety of actinobacterial bioactive molecules and their benefits for diverse industrial applications such as agriculture, aquaculture, biofuel production and food technology. Actinobacteria are one of the most promising sources of small bioactive molecules and it is estimated that only a small percentage of actinobacterial bioactive chemicals have been discovered to date. Identifying new diverse gene clusters of biotechnological relevance in the genome of Actinobacteria will be crucial to developing advanced applications for pharmaceutical, industrial and agricultural purposes. The book offers a unique resource for all graduate students, researchers and practitioners in the fields of microbiology, microbial biotechnology, and the genetic engineering of Actinobacteria.


Actinobacteria

Actinobacteria

Author: Dharumadurai Dhanasekaran

Publisher: BoD – Books on Demand

Published: 2016-02-11

Total Pages: 401

ISBN-13: 9535122487

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This book presents an introductory overview of Actinobacteria with three main divisions: taxonomic principles, bioprospecting, and agriculture and industrial utility, which covers isolation, cultivation methods, and identification of Actinobacteria and production and biotechnological potential of antibacterial compounds and enzymes from Actinobacteria. Moreover, this book also provides a comprehensive account on plant growth-promoting (PGP) and pollutant degrading ability of Actinobacteria and the exploitation of Actinobacteria as ecofriendly nanofactories for biosynthesis of nanoparticles, such as gold and silver. This book will be beneficial for the graduate students, teachers, researchers, biotechnologists, and other professionals, who are interested to fortify and expand their knowledge about Actinobacteria in the field of Microbiology, Biotechnology, Biomedical Science, Plant Science, Agriculture, Plant pathology, Environmental Science, etc.


The Fungal Kingdom

The Fungal Kingdom

Author: Joseph Heitman

Publisher: John Wiley & Sons

Published: 2020-07-10

Total Pages: 1136

ISBN-13: 1555819583

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Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.


Progress in the Chemistry of Organic Natural Products 108

Progress in the Chemistry of Organic Natural Products 108

Author: A. Douglas Kinghorn

Publisher: Springer

Published: 2019-03-28

Total Pages: 301

ISBN-13: 3030010996

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The first contribution summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described. The second contribution provides a detailed survey of the so far reported literature data on the capacities of selected oxyprenylated phenylpropanoids and polyketides to trigger receptors, enzymes, and other types of cellular factors for which they exhibit a high degree of affinity and therefore evoke specifice responses. And the third contribution discusses aspects of endophytic actinobacterial biology and chemistry, including biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives fo the future of microbial biodiscovery, with emphasis on the seondary metabolism of endophytic actinobacteria.


Basic Biology and Applications of Actinobacteria

Basic Biology and Applications of Actinobacteria

Author: Shymaa Enany

Publisher: BoD – Books on Demand

Published: 2018-12-05

Total Pages: 133

ISBN-13: 1789846145

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Actinobacteria have an extensive bioactive secondary metabolism and produce a huge amount of naturally derived antibiotics, as well as many anticancer, anthelmintic, and antifungal compounds. These bacteria are of major importance for biotechnology, medicine, and agriculture. In this book, we present the experience of worldwide specialists in the field of Actinobacteria, exploring their current knowledge and future prospects.


Secondary Metabolites

Secondary Metabolites

Author: Ramasamy Vijayakumar

Publisher: BoD – Books on Demand

Published: 2018-09-05

Total Pages: 149

ISBN-13: 1789236428

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This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.