In this issue of Urologic Clinics, guest editors Leonard G. Gomella and Veda Giri bring their considerable expertise to the topic of Prostate Cancer Genetics: Changing the Paradigm of Care. - Provides in-depth, clinical reviews on Prostate Cancer Genetics, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
With guidance from Consulting Editor, Dr. Kevin Loughlin, Dr. Deepak Kapoor has created a state-of-the-art issue devoted to the future of the urologist's clinical practice. Expert authors have contributed clinical review articles on the following topics: Workforce Issues in Urology; Development of Physician Leaders; Physician Burnout; Telemedicine; Understanding the Millenial Physician; The role of APPs in Urology; The impact of private equity transaction on urology; The growth of integrated care models in urology; Current and Future Status of Merit-Based Incentive Payment Systems; Advocacy and Health Policy; How to Subspecialize in Large Group Practices; Drug Prices: Strategies to Help Your Patients Manage the High Cost of Drugs; Operationalizing Clinical Research. Urologists will come away with the information they need to improve their expertise in their urologic practices and to improve patient outcomes.
Under the direction of New Consulting Editor, Dr. Kevin Loughlin, Guest Editors Drs. Jim C. Hu and Jonathan Shoag have put together a state-of-the-art monograph on robotics in urologic surgery. Not only do expert authors present current status and advances in this field, but they also look at what the future of robotic urologic surgery will mean for urologists and patients. Clinical review articles are devoted to the following topics: Robotic Ureteral Reconstruction; Robotic Prostatectomy: Technical Modifications that Improve Outcomes; Robotic Radical Cystectomy; Robotic Urology Training; Robotic Prostatectomy Quality Improvements; Robotic Lower Urinary Tract Reconstruction; Incorporating AI into GU Endoscopy; Competing Robotic Systems: A Preview; Robotic Intracorporeal Diversion; Robotic Reconstruction in Pediatric Urology; Robotic Partial Nephrectomy: Update on Techniques; Robotics in Male Infertility; Transperineal Biopsy; Robotic-Assisted Surgery for Upper-Tract TCC; and Retzius-Sparing Robotic Prostatectomy. Urologists will come away with the information they need to stay on top of advances in the area of robotic surgery.
The Guest Editors of this issue of Urologic Clinics of North America have put together a comprehensive collection of articles that provides the current knowledge on urologic cancer immunotherapy. Expert authors have contributed clinical review articles on the following topics: Era of personalized vaccines for GU cancers; TCR and dendritic vaccine platforms for GU cancers; Neo-adjuvant platforms for GU cancer immunotherapy; Immune-editing in Cancer: Role of tumor microenvironment and immune-suppressive pathways in localized and aggressive disease; Clinical integration of neo-adjuvant platforms for prostate cancer immunotherapy; Immunotherapy for muscle and non-muscle invasive bladder cancer: BCG and beyond; Immunotherapy for metastatic bladder cancer; Immunotherapy options for metastatic castrate-resistant prostate cancer; Role of tissue infiltrating lymphocytes: Understanding TCR; Therapeutic platforms for IPSC-derived CAR-T; Immune-suppression in prostate cancer: Underlying causes and influence on response to immunotherapy; and Racial disparity in response to immunotherapy. Urologists will come away with the most current information they need to improve outcomes in the urologic cancer patient.
In this issue of Urologic Clinics, Guest Editors Alan W Shindel and Tom F. Lue bring their considerable expertise to the topic of Sexual Dysfunction. Top experts in the field cover key topics such as Sexual Wellness in transgender persons; Energy-based Therapies for ED; Oncology Survivorship and Sexual Wellness for Men and Women; Sexual Wellness in Gay, Lesbian, and Bisexual Patients; and more. - Provides in-depth, clinical reviews in Sexual Dysfunction, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 16 relevant, practice-oriented topics including Management of Penile Fracture; Physiology of Erection and Pathophysiology of Erectile Dysfunction; Stem Cell and Gene-Based Therapy for ED; Management of Priapism; and more.
This issue of Urologic Clinics provides the urologist with important updates to better manage patients requiring minimally invasive procedures. Top experts in the field cover key topics such as Focal Therapy in Urology, Advances in Ureteroscopy, New Stent Technologies, and more. - Provides in-depth, clinical reviews on minimally invasive urology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 12 relevant, practice-oriented topics including New Lasers for Kidney Stone Treatment; New Technologies for Treatment of BPH; Technology for 3D Printing and Simulation; Artificial Intelligence: Applications in Urology; Disposable Endoscopes in Urology: Current State and Future Prospects; and more.
In this issue of Urologic Clinics of North America, guest editor Dr. Craig V. Comiter brings his considerable expertise to the topic of Urologic Pharmacology. Medical therapies for benign prostatic hyperplasia, erectile dysfunction, hypogonadism, overactive bladder, and prostate cancer are widely available, and a basic understanding of the pharmacology of existing treatment options are necessary to avoid complications and maximize efficacy associated with patient outcomes. In this issue, top experts in the field provide current clinical information to help urologists effectively and quickly treat patients. - Contains 14 relevant, practice-oriented topics including medical treatment for benign prostatic hyperplasia, medical treatment for urinary tract infections, nutraceuticals and phytotherapy in men's health, hormonal therapy for prostate cancer, medical treatment of female sexual dysfunction, and more. - Provides in-depth clinical reviews on urologic pharmacology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Completely updated to reflect the latest developments in science and technology, the second edition of this reference presents the diagnostic imaging tools essential to the detection, diagnosis, staging, treatment planning, and post-treatment management of cancer in both adults and children. Organized by major organs and body systems, the text offers comprehensive, abundantly illustrated guidance to enable both the radiologist and clinical oncologist to better appreciate and overcome the challenges of tumor imaging. Features 12 brand-new chapters that examine new imaging techniques, molecular imaging, minimally invasive approaches, 3D and conformal treatment planning, interventional techniques in radiation oncology, interventional breast techniques, and more. Emphasizes practical interactions between oncologists and radiologists. Includes expanded coverage of paediatric tumours as well as thorax, gastrointestinal tract, genitourinary, and musculoskeletal cancers. Offers reorganized and increased content on the brain and spinal cord. Nearly 1,400 illustrations enable both the radiologist and clinical oncologist to better appreciate and overcome the challenges of tumour imaging. - Outstanding Features! Presents internationally renowned authors' insights on recent technological breakthroughs in imaging for each anatomical region, and offers their views on future advances in the field. Discusses the latest advances in treatment planning. Devotes four chapters to the critical role of imaging in radiation treatment planning and delivery. Makes reference easy with a body-system organisation.
Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
