Precision Medicine and Translational Research in Urological Oncology
Author: Rong Na
Publisher: Frontiers Media SA
Published: 2022-08-01
Total Pages: 121
ISBN-13: 2889766721
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A National Cancer Clinical Trials System for the 21st Century
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2010-07-08
Total Pages: 317
ISBN-13: 0309157870
DOWNLOAD EBOOKThe National Cancer Institute's (NCI) Clinical Trials Cooperative Group Program has played a key role in developing new and improved cancer therapies. However, the program is falling short of its potential, and the IOM recommends changes that aim to transform the Cooperative Group Program into a dynamic system that efficiently responds to emerging scientific knowledge; involves broad cooperation of stakeholders; and leverages evolving technologies to provide high-quality, practice-changing research.
Personalized Medicine for Urological Cancers: Targeting Cancer Metabolism
Author: Eugenio Zoni
Publisher: Frontiers Media SA
Published: 2022-03-28
Total Pages: 129
ISBN-13: 2889748138
DOWNLOAD EBOOKUrologic Oncology
Author: Timothy L. Ratliff
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 369
ISBN-13: 1461328438
DOWNLOAD EBOOKThe study of genitourinary tumors is an area of recent rapid growth both in the understanding of disease processes and in the development of new diagnostic and therapeutic modalities. During rapid growth phases within any field, it is desirable to reflect on the current 'state of the art'. It is difficult even for experts in reputed areas of advancement to distinguish true advances from false leads, but it is far more difficult yet for those whose expertise lies in other areas to evaluate important advances. Thus, an objective assessment of evolving areas of investigation in the form of a comprehensive review is of considerable value. we have attempted to provide the reader with an over In this volume, view of some of the current areas of investigation in urologic oncology by experts in each area. There often is a tendency for invited papers in books of this nature to lack important critical peer review and therefore, suffer from a lack of objectivity. We have attempted to diminish this problem by the selection of two experts to discuss each subject. We believe that this format has improved the overall quality of the book for two reasons: 1) the know ledge of each contributor that his or her work would be reviewed by a peer 2) the fact that contributions by encourages more rigorous scholarship, and two experts, including the individual insights of each, provides a better per spective for the reader.
Oxford Textbook of Oncology
Author: David J. Kerr
Publisher: Oxford University Press
Published: 2016-01-28
Total Pages: 2837
ISBN-13: 0191065110
DOWNLOAD EBOOKWritten and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.
Lung Cancer and Personalized Medicine
Author: Aamir Ahmad
Publisher: Springer
Published: 2015-12-14
Total Pages: 236
ISBN-13: 3319242237
DOWNLOAD EBOOKThis, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies.
'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine
Author: Nosheen Masood
Publisher: Springer Nature
Published: 2020-03-20
Total Pages: 498
ISBN-13: 9811510679
DOWNLOAD EBOOKThis book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
50 Studies Every Urologist Should Know
Author: Philipp Dahm
Publisher: Oxford University Press
Published: 2021-02-26
Total Pages: 352
ISBN-13: 0190655364
DOWNLOAD EBOOK50 Studies Every Urologist Should Know presents key studies that have shaped the practice of urology. Selected using a rigorous methodology, the studies cover topics including reflux disease in paediatric urology, management of male erectile dysfunction and lower urinary tract symptoms, female urology and stone disease, the various forms of genitourinary cancer, and more. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for healthcare professionals in urology, as well as anyone who wants to learn more about the data behind clinical practice.
Personalized Medicine in the Making
Author: Chiara Beneduce
Publisher: Springer Nature
Published: 2022-03-07
Total Pages: 334
ISBN-13: 3030748049
DOWNLOAD EBOOKThis book offers a multidisciplinary look at the much-debated concept of “personalized medicine”. By combining a humanistic and a scientific approach, the book builds up a multidimensional way to understand the limits and potentialities of a personalized approach in medicine and healthcare. The book reflects on personalized medicine and complex diseases, the relationship between personalized medicine and the new bio-technologies, personalized medicine and personalized nutrition, and on some ethical, political, economic, and social implications of personalized medicine. This volume is of interest to researchers from several disciplines including philosophy, bio-medicine, and the social sciences. Chapter 16, “The Impact of Fantasy” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Principles of Translational Science in Medicine
Author: Martin Wehling
Publisher: Academic Press
Published: 2021-07-15
Total Pages: 495
ISBN-13: 032399962X
DOWNLOAD EBOOKPrinciples of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. - Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine - Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology - Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization
