Photobiomodulation in the Brain

Photobiomodulation in the Brain

Author: Michael R. Hamblin

Publisher: Academic Press

Published: 2019-07-13

Total Pages: 658

ISBN-13: 0128153067

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Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology and Neuroscience presents the fundamentals of photobiomodulation and the diversity of applications in which light can be implemented in the brain. It will serve as a reference for future research in the area, providing the basic foundations readers need to understand photobiomodulation's science-based evidence, practical applications and related adaptations to specific therapeutic interventions. The book covers the mechanisms of action of photobiomodulation to the brain, and includes chapters describing the pre-clinical studies and clinical trials that have been undertaken for diverse brain disorders, including traumatic events, degenerative diseases and psychiatric disorders. - Provides a much-needed reference on photobiomodulation with an unprecedented focus on the brain and its disorders - Features a body of world-renowned editors and chapter authors that promote research, policy and funding - Discusses the recent and rapid accumulation of literature in this area of research and the shift towards the use of non-invasive techniques in therapy


Low-level Light Therapy

Low-level Light Therapy

Author: Michael R. Hamblin

Publisher: SPIE-International Society for Optical Engineering

Published: 2017-11

Total Pages:

ISBN-13: 9781510614154

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"Low-level laser therapy (or photobiomodulation therapy) is a rapidly growing approach to treating a wide range of diseases and disorders that afflict humanity. This Tutorial Text covers the basic molecular and cellular mechanisms of action, applications for treating diseases in animal models, and its use in clinical trials and therapeutic practice in patients. Other topics include the two basic chromophores and how they trigger the signaling pathways, activation of transcription factors, and mobilization of stem cells; how the light-source design and the relevant energy parameters can affect the outcome of therapy; and the physics and tissue-optics principles that concern LLLT"--


Run in the Light

Run in the Light

Author: John Mitrofanis

Publisher: Morgan & Claypool Publishers

Published: 2019-08-05

Total Pages: 172

ISBN-13: 1643277200

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Parkinson's disease is a neurological disorder with cardinal motor signs of resting tremor, bradykinesia and lead-pipe rigidity. In addition, many patients display non-motor symptoms, including a diminished sensation of smell, gastrointestinal problems, various disorders of sleep and some cognitive impairment. These clinical features - particularly the motor signs - manifest after a progressive death of many dopaminergic neurones in the brain. Although currently available, conventional therapies can reduce the signs of the disease, the progression of this neuronal death has proved difficult to slow or stop, and the condition is relentlessly progressive. Hence, there is a real need to develop a treatment that is neuroprotective, one that slows the pathology of the disease effectively. At present, there are several neuroprotective therapies in the experimental pipeline, but these are for the patients of tomorrow. This book focuses on two therapies that are readily available for the patients of today. They involve the use of exercise and light (i.e. photobiomodulation, the use of red to infrared light therapy (λ=600-1070nm) on body tissues). The two therapies are tied together in several ways. First, in animal models of Parkinson's disease, they each have been shown to offer the key feature of neuroprotection, stimulating a series of built-in protective mechanisms within the neurones, that helps their survival, to self-protect and/or self-repair. There are also some promising indications of neuroprotection and many beneficial outcomes in parkinsonian patients. Further, both exercise and light therapies are similar in that they are non-invasive and safe to use, with no known adverse side-effects, making their combination with the conventional therapies, such as dopamine replacement drug therapy and deep brain stimulation, all the more feasible. Given the heterogeneity of Parkinson's disease in humans, tackling the condition from a range of different angles - with a number of different therapies - would only serve to enhance the positive outcomes. This book considers the use of exercise and light therapies, proposing that they have the potential to make a powerful "dynamic duo", offering a most effective neuroprotective treatment option to patients.


Handbook of Low-Level Laser Therapy

Handbook of Low-Level Laser Therapy

Author: Michael R. Hamblin

Publisher: CRC Press

Published: 2016-10-14

Total Pages: 1073

ISBN-13: 1315341174

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Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old, and recently has been getting increasing acceptance from the scientific, medical, and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action, the range of diseases that can be treated is also rising, and home use LED devices are becoming common. This book compiles cutting-edge contributions from the world’s leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT.


Photomedicine and Stem Cells

Photomedicine and Stem Cells

Author: Heidi Abrahamse

Publisher: Morgan & Claypool Publishers

Published: 2017-12-20

Total Pages: 109

ISBN-13: 1681743221

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Janus, the ancient Roman god depicted with two faces is an appropriate metaphor for light therapy. In the right photodynamic therapy conditions, light is able to kill nearly anything that is living such as cancers, microorganisms, parasites, and more. On the opposite face, light of the correct wavelength and proper dose (photobiomodulation) can heal, regenerate, protect, revitalize and restore any kind of dead, damaged, stressed, dying, degenerating cells, tissue, or organ system. This book discusses both sides of Janus' face in regards to light therapy.


Models of the Mind

Models of the Mind

Author: Grace Lindsay

Publisher: Bloomsbury Publishing

Published: 2021-03-04

Total Pages: 401

ISBN-13: 1472966457

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The human brain is made up of 85 billion neurons, which are connected by over 100 trillion synapses. For more than a century, a diverse array of researchers searched for a language that could be used to capture the essence of what these neurons do and how they communicate – and how those communications create thoughts, perceptions and actions. The language they were looking for was mathematics, and we would not be able to understand the brain as we do today without it. In Models of the Mind, author and computational neuroscientist Grace Lindsay explains how mathematical models have allowed scientists to understand and describe many of the brain's processes, including decision-making, sensory processing, quantifying memory, and more. She introduces readers to the most important concepts in modern neuroscience, and highlights the tensions that arise when the abstract world of mathematical modelling collides with the messy details of biology. Each chapter of Models of the Mind focuses on mathematical tools that have been applied in a particular area of neuroscience, progressing from the simplest building block of the brain – the individual neuron – through to circuits of interacting neurons, whole brain areas and even the behaviours that brains command. In addition, Grace examines the history of the field, starting with experiments done on frog legs in the late eighteenth century and building to the large models of artificial neural networks that form the basis of modern artificial intelligence. Throughout, she reveals the value of using the elegant language of mathematics to describe the machinery of neuroscience.


Laser Therapy in Veterinary Medicine

Laser Therapy in Veterinary Medicine

Author: Ronald J. Riegel

Publisher: John Wiley & Sons

Published: 2017-05-30

Total Pages: 514

ISBN-13: 1119220114

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Laser Therapy in Veterinary Medicine: Photobiomodulation is a complete guide to using therapeutic lasers to treat veterinary patients, focusing on practical information. Offers a comprehensive resource for incorporating therapeutic lasers in veterinary practice Focuses on practical information tailored for the veterinary clinic Written by 37 leading experts in veterinary laser therapy Provides a thorough foundation on this standard-of-care modality Emphasizes clinical applications with a real-world approach


Handbook of Photomedicine

Handbook of Photomedicine

Author: Michael R. Hamblin

Publisher: Taylor & Francis

Published: 2013-10-22

Total Pages: 854

ISBN-13: 1439884706

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Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to di


The Brain and Behavior

The Brain and Behavior

Author: David L. Clark

Publisher: Cambridge University Press

Published: 2005-09-08

Total Pages: 290

ISBN-13: 9780521840507

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New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.


Solving the Brain Puzzle

Solving the Brain Puzzle

Author: Bill Code

Publisher: FriesenPress

Published: 2019-01-21

Total Pages: 618

ISBN-13: 1525527258

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Receiving a diagnosis of multiple sclerosis (MS), Alzheimer’s disease, Parkinson’s disease, or some other brain-related illness is devastating. It feels like life, as you know it, is over, and you are powerless to do anything about it. Your future may seem like nothing but a long black tunnel of decreasing cognitive function, declining mobility, depression, and premature death. Even your physician may share this gloomy view. The good news is, you have more control over your brain health than you think! With the exception of cancer, many brain illnesses can be reversed through a combination of diet, exercise, supplements, proper sleep, avoiding and removing toxins from the body, and taking an epigenetic (turning good genes on and not-so-good genes off) approach to your healing. Several “jump start” techniques, including oxygen therapy, microbiota therapy (Gut Flora Transplant or GFT), photobiomodulation therapy (PMT), venous angioplasty, and even cannabis can enhance your recovery in as little as a few weeks. Never before have we had so many safe approaches with little or no side effects. Best of all, these treatments are now available on almost every continent, including Europe, Asia, Australia, and North America. It is time we let go of our paternalistic concept that “doctor knows best.” This book describes all the above treatments and more, providing a roadmap to enhance your brain recovery. You may not feel like it right now, but you can win the brain game, and this book can show you how!