Peroxynitrite Detection in Biological Media
Peroxynitrite Detection in Biological Media

Author: Serban Peteu

Publisher: Royal Society of Chemistry

Published: 2015-10-16

Total Pages: 251

ISBN-13: 1782622357

DOWNLOAD EBOOK

Peroxynitrite is a powerful oxidiser which can damage a wide array of molecules within cells, including DNA and proteins, leading to apoptosis, inflammation or cancer. Peroxynitrite detection and quantification provides critical information in understanding its biological implications. Attempts to investigate the behavior of peroxynitrite in vivo and in vitro have been hampered by the difficulty in detecting this highly reactive oxygen species. This book presents the current state of the art in this research field with contributions from scientific leaders in the field. The chapters make clear the associated challenges and development for selective and sensitive detection of peroxynitrite. This book is a timely addition to the literature, as the first in the field, dedicated to detecting this molecule in vivo. It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers.

Biological Fluid-Surface Interactions in Detection and Medical Devices
Biological Fluid-Surface Interactions in Detection and Medical Devices

Author: Michael Thompson

Publisher: Royal Society of Chemistry

Published: 2017

Total Pages: 304

ISBN-13: 1782620974

DOWNLOAD EBOOK

This book examines the interactions between implants and biological fluids that cause fouling in biosensors and the serious issue of thrombus formation suitable for professional researchers in academia and industry and postgraduate students.

Field-effect Transistor Biosensors for Rapid Pathogen Detection
Field-effect Transistor Biosensors for Rapid Pathogen Detection

Author: Naif H M Al-Hardan

Publisher: Royal Society of Chemistry

Published: 2024-05-03

Total Pages: 211

ISBN-13: 1837673438

DOWNLOAD EBOOK

Looking to prevent future outbreaks of deadly pathogens by early detection? Infectious diseases continue to be a challenge that necessitates increased precision in detection and integration to achieve accurate diagnosis at the point of care (PoC). Field-effect transistors (FETs) have been investigated widely as biosensors for pathogen detection, with advantages such as label-free and real-time detection capabilities. These biosensors have: a high level of sensitivity, a remarkable capacity for miniaturization, a molecular minimum limit of detection (LoD), and seamless integration with semiconductor technology In this title, we have invited expert scientific researchers to share their experience in this field. This book focuses on the application and possibility of FETs as biosensors, for rapid and real time detection of pathogens that affect human life. The lack of commercially available efficient devices that can be deployed for this task resulted in the recent global spread of the SARS-CoV-19 virus. The book is an attempt to keep interested parties up to date. Aimed at scientists and engineers (researchers, academics, and postgraduate students) who are interested in developing and using BioFET based sensors, the information in this book is crucial to help prevent future outbreaks of pathogens which bring with them significant impacts on human health and wellbeing.

Challenges in Detection Approaches for Forensic Science
Challenges in Detection Approaches for Forensic Science

Author: Lynn Dennany

Publisher: Royal Society of Chemistry

Published: 2021-04-13

Total Pages: 205

ISBN-13: 1839160942

DOWNLOAD EBOOK

Forensic science combines analytical science with the requirements of law enforcement agencies and legislation. This can often pose challenges within the development of novel analytical methods, particularly with the drive to have more in-field and in-situ applications to facilitate the investigation of criminal cases. This book will explore the specific challenges encountered by forensic scientists and the developments that are being made to address these within the framework of the legislative requirements. It will provide a critical appraisal of the current challenges facing analytical approaches for the detection of forensic evidence and the state of the art technologies used to address these challenges. Providing an excellent combination of current research and how this pertains to forensic investigations, the book will also highlight key obstacles within this ever-changing environment. Aimed at graduates and forensic professionals, this is a unique oversight of the current work being undertaken within the development of analytical methods and also in the interpretation of complex crime scene samples.

Surfactant-based Sensors in Chemical and Biochemical Detection
Surfactant-based Sensors in Chemical and Biochemical Detection

Author: J G Manjunatha

Publisher: Royal Society of Chemistry

Published: 2023-10-11

Total Pages: 207

ISBN-13: 1837671192

DOWNLOAD EBOOK

Describing the importance of surfactants in electrochemical investigations related to biologically and environmentally vital chemicals, this book charts the progression of highly responsive electrochemical sensors using surfactants as a modifying agent in the sensor field. It provides contributed chapters from respected researchers on information concerning the activity of target molecules and electron transfer kinetics arising at the surface of the fabricated sensor materials. Surfactant-based electrochemical sensors are of great interest in the quest to find low-cost, fast and highly responsive sensing devices and one aim of this book is to help improve the competence and knowledge in this newly emerging interdisciplinary research area. Attracting an audience of students, academics, industrialists and engineers, it will interest researchers seeking to use non-toxic sensors in their detection challenges.

Detection Methods in Precision Medicine
Detection Methods in Precision Medicine

Author: Mengsu Yang

Publisher: Royal Society of Chemistry

Published: 2020-12-14

Total Pages: 389

ISBN-13: 1788017617

DOWNLOAD EBOOK

This book will be among the first to cover the detection methods for precision medicine that are set to transform health care in the future.

Quenched-phosphorescence Detection of Molecular Oxygen
Quenched-phosphorescence Detection of Molecular Oxygen

Author: Dmitri B Papkovsky

Publisher: Royal Society of Chemistry

Published: 2018-05-25

Total Pages: 384

ISBN-13: 1788014553

DOWNLOAD EBOOK

Significant progress has been made in recent years in quenched-phosphorescence oxygen sensing, particularly in the materials and applications of this detection technology that are open to commercialization, like uses in brain imaging and food packaging. Prompted by this, the editors have delivered a dedicated book that brings together these developments, provides a comprehensive overview of the different detection methodologies, and representative examples and applications. This book is intended to attract new researchers from various disciplines such as chemistry, physics, biology and medicine, stimulate further progress in the field and assist in developing new applications. Providing a concise summary at the cutting edge, this practical guide for current experts and new potential users will increase awareness of this versatile sensing technology.

Disposable Electrochemical Sensors for Healthcare Monitoring
Disposable Electrochemical Sensors for Healthcare Monitoring

Author: A Pandikumar

Publisher: Royal Society of Chemistry

Published: 2021-04-29

Total Pages: 360

ISBN-13: 1839163372

DOWNLOAD EBOOK

Disposable electrodes have been widely used as a sensing platform in electrical and electrochemical sensors owing to the possibility of quantitative detection using clinical biomarkers with high precision, sensitivity and reproducibility, which are necessary for accurate diagnosis of the health condition of an individual. This book focusses on the emerging disposable electrochemical sensors in the health sector and the advancement of analytical devices to monitor diabetic, cancer and cardiovascular patients using different nanomaterials. It discusses the upcoming strategies, advantages and the limitations of the existing devices using disposable electrodes. Uniquely, it covers in-depth knowledge of mechanistic features of various designs of screen-printing electrodes and the material aspects required of sensors developed for the healthcare field. It also looks at the portable devices using a variety of materials and the future directions for research in this area. Appealing to the health care industry, this book is aimed at academic and research institutes at both the graduate and postgraduate level. The contributors are leading experts in the field and they are providing guidance for the next decade of research in the field of disposable electrochemical biosensors.

Lab-on-a-chip Devices for Advanced Biomedicines
Lab-on-a-chip Devices for Advanced Biomedicines

Author: Arpana Parihar

Publisher: Royal Society of Chemistry

Published: 2024-08-14

Total Pages: 694

ISBN-13: 1837673489

DOWNLOAD EBOOK

The global miniature devices market is poised to surpass a valuation of $12–$15 billion USD by the year 2030. Lab-on-a-chip (LOC) devices are a vital component of this market. Comprising a network of microchannels, electrical circuits, sensors, and electrodes, LOC is a miniaturized integrated device platform used to streamline day-to-day laboratory functions, run cost-effective clinical analyses and curb the need for centralized instrumentation facilities in remote areas. Compact design, portability, ease of operation, low sample volume, short reaction time, and parallel investigation stand as the pivotal factors driving the widespread acceptance of LOC within the biomedical community. In this book, the Editors meticulously explore LOC through three key ‘Ts’: Theories (microfluidics, microarrays, instrumentation, software); Technologies (additive manufacturing, artificial intelligence, computational thinking, smart consumables, scale-up tactics, and biofouling); and Trends (biomedical analysis, point-of-care diagnostics, personalized healthcare, bioactive synthesis, disease diagnosis, and space applications) This comprehensive text not only provides readers with a thorough understanding of the current advancements in the LOC domain but also offers valuable insights to support the utilization of miniaturized devices for enhanced healthcare practices. Aimed at career researchers looking for instruction in the topic and newcomers to the area, the book is also useful for undergraduate and postgraduate students embarking on new studies or for those interested in reading about the LOC platform.