Overcoming Resistance to Systemic Therapy in Breast Cancer
Author: Zhi-Gang Zhuang
Publisher: Frontiers Media SA
Published: 2023-12-29
Total Pages: 183
ISBN-13: 2832541887
DOWNLOAD EBOOKRead and Download eBook Full
Author: Zhi-Gang Zhuang
Publisher: Frontiers Media SA
Published: 2023-12-29
Total Pages: 183
ISBN-13: 2832541887
DOWNLOAD EBOOKAuthor: Zodwa Dlamini
Publisher: Springer Nature
Published:
Total Pages: 390
ISBN-13: 3031528603
DOWNLOAD EBOOKAuthor: Dihua Yu
Publisher: Springer Science & Business Media
Published: 2009-12-30
Total Pages: 175
ISBN-13: 0387740392
DOWNLOAD EBOOKIn Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem, the book then focuses on the latest findings of molecular mechanisms of drug resistance. Coverage provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment. It allows those who are interested in breast cancer therapy to get a jump-start on critical issues in breast cancer therapeutic resistance.
Author: Prajakta Shirish Oak
Publisher:
Published: 2012
Total Pages: 204
ISBN-13:
DOWNLOAD EBOOKAuthor: Gw Sledge
Publisher: Clinical Pub
Published: 2012-06
Total Pages: 0
ISBN-13: 9781846920660
DOWNLOAD EBOOKThis new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.
Author: Maria Rosaria De Miglio
Publisher: Frontiers Media SA
Published: 2023-02-03
Total Pages: 178
ISBN-13: 2832513654
DOWNLOAD EBOOKAuthor: Manmeet Ahluwalia
Publisher: Springer Nature
Published: 2019-11-05
Total Pages: 421
ISBN-13: 3030234177
DOWNLOAD EBOOKThis book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
Author: William R. Miller
Publisher: CRC Press
Published: 2002-03-08
Total Pages: 395
ISBN-13: 0203909836
DOWNLOAD EBOOKThis reference evaluates and describes the latest strategies for hormone suppression and blockade in the management of early and advanced stage breast cancer and explores the effects of tamoxifen, selective estrogen receptor modulators (SERMs), aromatase inhibitors, and their combination on both breast cancers and normal tissues. Endocrine T
Author: Jun Zhou
Publisher: Humana Press
Published: 2012-08-09
Total Pages: 492
ISBN-13: 9781617796647
DOWNLOAD EBOOKChemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .
Author: Oreste Gentilini
Publisher: Springer Nature
Published: 2020-02-07
Total Pages: 218
ISBN-13: 3030247627
DOWNLOAD EBOOKThis contributed book covers all aspects concerning the clinical scenario of breast cancer in young women, providing physicians with the latest information on the topic. Young women are a special subset of patients whose care requires dedicated expertise. The book, written and edited by internationally recognized experts who have been directly involved in the international consensus guidelines for breast cancer in young women, pays particular attention to how the disease and its planned treatment can be effectively communicated to young patients. Highly informative and carefully structured, it provides both theoretical and practice-oriented insight for practitioners and professionals involved in the different phases of treatment, from diagnosis to intervention, to follow-up – without neglecting the important role played by prevention.