Organized Multienzyme Systems: Catalytic Properties
Organized Multienzyme Systems: Catalytic Properties

Author: G. Rickey Welch

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 473

ISBN-13: 0323149103

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Organized Multienzyme Systems: Catalytic Properties describes the kinetic and catalytic properties of organized enzyme systems. This book is composed of nine chapters that specifically cover both immobilized and naturally occurring systems. The first two chapters examine the nature and function of enzyme organization in the mitochondrion, as well as the structural/functional coupling of the components in energy-transducing membrane systems. These topics are followed by discussions on ""dynamic compartmentation"" in soluble multienzyme systems; the allosteric enzyme systems; and allosterism in reversibly adsorptive enzyme systems. Other chapters explore model studies with specific immobilized multienzyme sequences, as regards the analysis of microenvironmental effects, and the mathematical exposition on the kinetic analysis of multienzyme systems in homogeneous solution. The last chapters present some theoretical and experimental studies on the behavior of immobilized systems. These chapters also provide a speculative integrative view of the kind of functional coherence that may be operative in organized states in vivo. This book is of great value to cell biologists, biochemists, and enzyme scientists and researchers.

Current Topics in Cellular Regulation
Current Topics in Cellular Regulation

Author: Bernard L. Horecker

Publisher: Elsevier

Published: 2014-06-28

Total Pages: 365

ISBN-13: 1483217280

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Current Topics in Cellular Regulation: Volume 29 is a collection of papers that deals with dynamic macromolecular interactions, ligand binding, multi-enzyme complex formation, the regulation of fatty acid uptake, and synthesis in mammary or adipose tissues. Other papers explain the functional relationships of guanosine triphosphate binding proteins, the glycogen storage disease, the regulation of the pentose phosphate pathway in the brain, as well as the regulation of carotenoid biosynthesis. One paper discusses the dissociable enzyme complexes stabilized by weak interactions, particularly on the interaction of cytosolic enzymes with the contractile apparatus, with membranes, or with functionally related enzymes. Another paper investigates the mechanism of acute regulation, in mammary epithelial cells, of the processes which collaborate to supply fatty acids for esterification to form glycerolipids (which is predominantly triacylglycerol). Glycerolipids comprise mostly the total lipid content of the secretory product of those cells—mammalian milk. The paper notes that a counter-regulatory hormone collaborating with insulin in the regulation of lipid metabolism in the lactating mammary cell, does not act via cyclic AMP. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology or physiology.

Computation In Cellular And Molecular Biological Systems
Computation In Cellular And Molecular Biological Systems

Author: Roy Cuthbertson

Publisher: World Scientific

Published: 1996-10-25

Total Pages: 377

ISBN-13: 9814498130

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Computation in Cellular and Molecular Biological Systems is a selection of papers presented at the First International Workshop on Information Processing in Cells and Tissues (IPCAT 95). The book contains contributions from mathematicians, biochemists, cell biologists, physiologists and computer scientists. It is multidisciplinary in nature and deals with integrative aspects of information processing, cellular systems and dynamical methods.

Emergent Collective Properties, Networks and Information in Biology
Emergent Collective Properties, Networks and Information in Biology

Author: J. Ricard

Publisher: Elsevier

Published: 2006-02-10

Total Pages: 295

ISBN-13: 0080462154

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The concept of network as a mathematical description of a set of states, or events, linked according to a certain topology has been developed recently and has led to a novel approach of real world. This approach is no doubt important in the field of biology. In fact biological systems can be considered networks. Thus, for instance, an enzyme-catalysed reaction is a network that links, according to a certain topology, the various states of the protein and of its complexes with the substrates and products of the chemical reaction. Connections between neurons, social relations in animal and human populations are also examples of networks. Hence there is little doubt that the concept of network transgresses the boundaries between traditional scientific disciplines. This book is aimed at discussing in physical terms these exciting new topics on simple protein model lattices, supramolecular protein edifices, multienzyme and gene networks. *Physical and mathematical approach of biological phenomena.*Offers biochemists and biologists the mathematical background required to understand the text.*Associates in the same general formulation, the ideas of communication of a message and organization of a system.*Provides a clear-cut definition and mathematical expression of the concepts of reduction, integration, emergence and complexity that were so far time-honoured and vague

Molecular and Cellular Enzymology
Molecular and Cellular Enzymology

Author: P. Jeanteur

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 160

ISBN-13: 3642785816

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Proteins constitute the working-class molecules of the cell. Hence, understanding the way they act is a prerequisite for understanding how a cell functions and how life evolves. Aspects such as the protein-ligand relationship, recognition, protein evolution by point mutation, enzyme-substrate interactions, behaviour of an enzyme in a living cell, control and dynamics of enzyme networks as well as the physico-chemical background of enzyme actions and multi-enzyme complexes are comprehensively treated in this volume.

Biological Complexity and the Dynamics of Life Processes
Biological Complexity and the Dynamics of Life Processes

Author: J. Ricard

Publisher: Elsevier

Published: 1999-11-01

Total Pages: 369

ISBN-13: 0080860958

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The aim of this book is to show how supramolecular complexity of cell organization can dramatically alter the functions of individual macromolecules within a cell. The emergence of new functions which appear as a consequence of supramolecular complexity, is explained in terms of physical chemistry. The book is interdisciplinary, at the border between cell biochemistry, physics and physical chemistry. This interdisciplinarity does not result in the use of physical techniques but from the use of physical concepts to study biological problems. In the domain of complexity studies, most works are purely theoretical or based on computer simulation. The present book is partly theoretical, partly experimental and theory is always based on experimental results. Moreover, the book encompasses in a unified manner the dynamic aspects of many different biological fields ranging from dynamics to pattern emergence in a young embryo. The volume puts emphasis on dynamic physical studies of biological events. It also develops, in a unified perspective, this new interdisciplinary approach of various important problems of cell biology and chemistry, ranging from enzyme dynamics to pattern formation during embryo development, thus paving the way to what may become a central issue of future biology.

Molecular System Bioenergetics
Molecular System Bioenergetics

Author: Valdur Saks

Publisher: John Wiley & Sons

Published: 2008-01-08

Total Pages: 633

ISBN-13: 3527621105

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In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.