Oral and Intravenous Bisphosphonate-induced Osteonecrosis of the Jaws
Author: Robert E. Marx
Publisher: Quintessence Publishing (IL)
Published: 2011
Total Pages: 0
ISBN-13: 9780867155105
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Author: Robert E. Marx
Publisher: Quintessence Publishing (IL)
Published: 2011
Total Pages: 0
ISBN-13: 9780867155105
DOWNLOAD EBOOKAuthor: John P. Bilezikian
Publisher: Wiley-Blackwell
Published: 2011-03-14
Total Pages: 100
ISBN-13:
DOWNLOAD EBOOK"This volume presents manuscripts stemming from the conference entitled 'Bisphosphonates & Osteonecrosis of the Jaw,' held May 19, 2007 at the New York Academy of Sciences
Author: Sven Otto
Publisher: Springer
Published: 2014-11-27
Total Pages: 216
ISBN-13: 3662437333
DOWNLOAD EBOOKOsteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists.
Author: Francesco Saverio De Ponte
Publisher: Springer Science & Business Media
Published: 2011-11-25
Total Pages: 186
ISBN-13: 8847020832
DOWNLOAD EBOOKDuring the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today's oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as the phosphorous vapors, and are absorbed into bone and ingested by osteoclasts. When this unique binding process of bisphosphonates to bone occurs, osteoclasts are poisoned, and this reduces or eliminates bone turnover. Alveolar bone in the mandible and maxilla turns over more rapidly than in long bones, so the jaws are a better target for bisphosphonate toxicity. It wasn't until 2003 that today's intravenous and oral nitrogen-containing bisphosphonate medications were implicated as major risk factors in the development of exposed necrotic bone of the jaws. Most of the researchers who reported cases of bisphosphonate-induced osteonecrosis of the jaw found that these patients were treated with zoledronate, pamidronate, or a combination of these drugs, which are commonly used for treating breast cancer or myeloma. In about 5% of cases, subjects with BIONJ were being treated for osteoporosis. Precipitating events that contribute to BIONJ are tooth extractions (about 50% of cases), mandibular exostoses, periodontal disease, and local trauma from ill-fitting dentures. It is not known if the placement of dental implants is a precipitating factor. The book aims to meet the need of medical practitioners working in all fields that use bisphosphonates, and to present the conservative and surgical treatment methods currently in use. There will also be detailed information on the literature relating to dental implants in patients treated with bisphosphonates.
Author: Kenneth E. Fleisher
Publisher: Thieme
Published: 2016-09-16
Total Pages: 125
ISBN-13: 3132412716
DOWNLOAD EBOOKA collaboration between some of the leading international experts in the field, AOCMF proudly presents Antiresorptive Drug-related Osteonecrosis of the Jaw (ARONJ)-a Guide to Research, which unravels the many biologic processes and risk factors associated with this debilitating condition. With its unknown pathophysiology, lack of established management regimens, and because of the millions of patients currently taking antiresorptive agents, this important book on ARONJ has been produced to provide the latest in contemporary evidence and insight. The book's key features include: Detailed analysis of the historical definitions, classifications, and clinical features of ARONJ Review of the risk factors and treatment options currently available, and why the jaw bone is predominantly affected Discussion on the use of large and small animals in modelling. With dozens of clinical images to help illustrate the impact of this condition on real patients, Antiresorptive Drug-related Osteonecrosis of the Jaw (ARONJ)-a Guide to Research is an excellent resource for anyone involved or interested in this important medical field.
Author: Robert E. Marx
Publisher:
Published: 2006
Total Pages: 172
ISBN-13:
DOWNLOAD EBOOKOral and Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws deals with dentistry.
Author: Marc Baltensperger
Publisher: Springer Science & Business Media
Published: 2008-11-07
Total Pages: 320
ISBN-13: 3540287663
DOWNLOAD EBOOK“Osteomyelitis of the Jaws” is the first textbook of its kind covering exclusively all aspects of this challenging disease. A clear classification of osteomyelitis of the jaws is provided. Clinical presentation and diagnosis are meticulously described and illustrated. Radiological imaging from conventional radiographs to CT, MRI and PET diagnosis are outlined for all types of osteomyelitis of the jaws. Pathology and Pathophysiology of this disease are described in a clear way. All therapeutic modalities from surgery to antibiotic and hyperbaric oxygen therapy are comprehensively outlined and discussed. Each type of Osteomyelitis of the jaws are additionally described and illustrated in case reports giving this book a very practical approach to the subject.
Author: Sarah Cousty
Publisher: Springer Nature
Published: 2021-05-24
Total Pages: 124
ISBN-13: 3030669734
DOWNLOAD EBOOKThis book provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance. It will be of value for all dental and medical practitioners who encounter these complications in their clinical practice.
Author: Reiner Bartl
Publisher: Springer
Published: 2019-02-06
Total Pages: 518
ISBN-13: 3030007316
DOWNLOAD EBOOKThis comprehensive manual covers all aspects of the prevention, diagnosis and management of osteoporosis, offering an upbeat and optimistic assessment of what can be achieved. While scientifically based, the book provides easy-to-follow guidelines for lifelong maintenance of skeletal structure and function. It deals with everything from the basic physiology of bone and mineral metabolism to the diagnostic utility of radiologic imaging and specialized tests and current treatment recommendations, including for fracture management. The relationship of osteoporosis to a variety of other disorders is also thoroughly explored and elucidated. Osteoporosis represents a global threat because every human being is vulnerable to it as time passes. The authors point out the enormous scale of the problem in terms of the human suffering, morbidity, and mortality on the one hand and the associated astronomical national and global costs on the other. Osteoporosis is preventable, and every doctor in every medical discipline can contribute to this goal. And though prevention is better than cure, it is never too late for effective therapy, as outlined in this book. Bone is every doctorʼs and every bodyʼs business!
Author: Robert E. Marx
Publisher:
Published: 2012
Total Pages: 0
ISBN-13: 9780867155129
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