Behavioral and Neural Genetics of Zebrafish
Behavioral and Neural Genetics of Zebrafish

Author: Robert T. Gerlai

Publisher: Academic Press

Published: 2020-04-03

Total Pages: 616

ISBN-13: 012817529X

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Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. - Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field - Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish - Features examples of zebrafish models of human central nervous system disorders - Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

The world according to zebrafish: How neural circuits generate behaviour
The world according to zebrafish: How neural circuits generate behaviour

Author: Gonzalo G. De Polavieja

Publisher: Frontiers E-books

Published: 2014-11-07

Total Pages: 368

ISBN-13: 2889193284

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Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.

Zebrafish Neurobehavioral Protocols
Zebrafish Neurobehavioral Protocols

Author: Allan V. Kalueff

Publisher: Humana Press

Published: 2011-04-06

Total Pages: 206

ISBN-13: 9781607619543

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As a model organism, zebrafish (Danio rerio) offer an opportunity to perform steadfast scientific investigations in a robust and high-throughput manner. In Zebrafish Neurobehavioral Protocols, experts in the field provide a series of detailed behavioral protocols dealing with the major current research areas in the field of behavioral neuroscience. The chapters discuss the use and interpretation of video-aided quantification of zebrafish behaviors, describe novel assays commonly used to quantify emotionality, learning, memory, and social behaviors in zebrafish, and instruct how to quantify endocrine responses and correlate them with behavior. Written in the Neuromethods series format, the chapters provide authoritative reviews of many commonly used approaches in the field today. This "how to" book will be a useful practical guide for zebrafish researchers and will complement another related book from this series, Zebrafish Models in Neurobehavioral Research. Cutting-edge and timely, Zebrafish Neurobehavioral Protocols serves as an excellent compilation epitomizing the growing potential of zebrafish in modern scientific inquiry.

Growing Points Ethology
Growing Points Ethology

Author: P. P. G. Bateson

Publisher: Cambridge University Press

Published: 1976-10-07

Total Pages: 564

ISBN-13: 9780521212878

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First published in 1976, this volume is a collection of essays by some of the most prominent and active ethologists. It is organized into four sections: motivation and perception, function and evolution, development, and human social relationships. The first three sections reflect the four questions which are basic to ethology: what were the immediate causes of a behaviour pattern; what is its biological function; how did it evolve; and how did it develop in the individual? The last section involves questions of all four types. The sections are introduced and linked by editorials and the book concludes with an important statement on asking the right questions. The essays are forward looking and identify areas of importance for the study of behaviour. The volume is a source of formative ideas for students, their teachers and research workers in a wide variety of disciplines in the biological psychological and social sciences.

Neural Mechanisms of Startle Behavior
Neural Mechanisms of Startle Behavior

Author: Robert C. Eaton

Publisher: Springer Science & Business Media

Published: 1984-10

Total Pages: 408

ISBN-13: 9780306415562

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In the past fifteen years there has been considerable interest in neural circuits that initiate behavior patterns. For many types of behaviors, this involves decision-making circuits whose primary elements are neither purely sensory nor motor, but represent a higher order of neural pro cessing. Of the large number of studies on such systems, analyses of startle circuits compose a major portion, and have been carried out on systems found throughout the animal kingdom. Startle has been an im portant model because of the reliability of the behavioral act for laboratory study and the accessibility of the underlying neural circuitry. However, probably because of the breadth of the subject, this material has never been reviewed in a comprehensive way that presents the elements com mon to startle circuits in the different animal systems in which they occur. This book presents a diversity of approaches based on a broad back ground of animal groups ranging from the earliest nervous systems in cnidarians to the most recently evolved and advanced in mammals. The behaviors themselves are all short latency, fast motor acts, when consid ered on the time scale of the organism, and involve avoidance or evasion, although in some cases we do not yet completely understand their natural role. These behaviors occur in response to stimuli that have sudden or unexpected onset.

Decoding Neural Circuit Structure and Function
Decoding Neural Circuit Structure and Function

Author: Arzu Çelik

Publisher: Springer

Published: 2017-07-24

Total Pages: 517

ISBN-13: 3319573632

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This book offers representative examples from fly and mouse models to illustrate the ongoing success of the synergistic, state-of-the-art strategy, focusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to answer this question: How do individual nerve cells functionally cooperate to guide behavioral responses? Two genetically tractable species, mice and flies, together significantly further our understanding of these processes. Current efforts focus on integrating knowledge gained from three interrelated fields of research: (1) understanding how the fates of different cell types are specified during development, (2) revealing the synaptic connections between identified cell types (“connectomics”) using high-resolution three-dimensional circuit anatomy, and (3) causal testing of how iden tified circuit elements contribute to visual perception and behavior.

The Neuroethology of Predation and Escape
The Neuroethology of Predation and Escape

Author: Keith T. Sillar

Publisher: John Wiley & Sons

Published: 2016-05-02

Total Pages: 403

ISBN-13: 0470972238

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THE NEUROETHOLOGY OF PREDATION AND ESCAPE To eat and not get eaten is key to animal survival, and the arms race between predators and prey has driven the evolution of many rapid and spectacular behaviours. This book explores the neural mechanisms controlling predation and escape, where specialisations in afferent pathways, central circuits, motor control and biomechanics can be traced through to natural animal behaviour. Each chapter provides an integrated and comparative review of case studies in neuroethology. Ranging from the classic studies on bat biosonar and insect counter-measures, through to fish-eating snails armed with powerful neurotoxins, the book covers a diverse and fascinating range of adaptations. Common principles of biological design and organization are highlighted throughout the text. The book is aimed at several audiences: for lecturers and students. This synthesis will help to underpin the curriculum in neuroscience and behavioural biology, especially for courses focusing on neuroethology for postgraduate students. The sections devoted to your area of specialism will give a flying start to your research reading, while the other chapters offer breadth and insights from comparative studies for academic researchers. The book will provide a valuable resource and an enjoyable read Above all, we hope this book will inspire the next generation of neuroethologists.

The Lateral Line System
The Lateral Line System

Author: Sheryl Coombs

Publisher: Springer Science & Business Media

Published: 2013-10-23

Total Pages: 360

ISBN-13: 1461488516

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The Lateral Line System provides an overview of the key concepts and issues surrounding the development, evolution, neurobiology, and function of the lateral line, a fascinating yet somewhat enigmatic flow-sensing system. The book examines the historical precedence for linking the auditory and lateral line systems, its structure and development, use of the lateral line system of zebrafish as a model system, physical principles governing the response properties of the lateral line, the behavioral relevance of this sensory system to the lives of fish, and an examination of how this information is shaped and encoded by the peripheral and central nervous systems. Contents The Gems of the Past: A Brief History of Lateral Line Research in the Context of the Hearing Sciences - Sheryl Coombs and Horst Bleckmann Morphological Diversity, Development, and Evolution of the Mechanosensory Lateral Line System - Jacqueline F. Webb The Hydrodynamic of Flow Stimuli - Matthew J. McHenry and James C. Liao The Biophysics of the Fish Lateral Line - Sietse M. van Netten and Matthew J. McHenry Sensory Ecology and Neuroethology of the Lateral Line - John Montgomery, Horst Bleckmann, and Sheryl Coombs Information Encoding and Processing by the Peripheral Lateral Line System - Boris Philippe Chagnaud and Sheryl Coombs The Central Nervous Organization of the Lateral Line System - Mario F. Wullimann and Benedikt Grothe Central Processing of Lateral Line Information - Horst Bleckmann and Joachim Mogdans Functional Overlap and Nonoverlap Between Lateral Line and Auditory Systems - Christopher B. Braun and Olav Sand The Hearing Loss, Protection, and Regeneration in the Larval Zebrafish Lateral Line - Allison B. Coffin, Heather Brignull, David W. Raible, and Edwin W Rubel

Handbook of Neurobehavioral Genetics and Phenotyping
Handbook of Neurobehavioral Genetics and Phenotyping

Author: Valter Tucci

Publisher: John Wiley & Sons

Published: 2017-03-06

Total Pages: 648

ISBN-13: 1118540719

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The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.