Spectral, Photon Counting Computed Tomography

Spectral, Photon Counting Computed Tomography

Author: Katsuyuki Taguchi

Publisher: CRC Press

Published: 2020-07-14

Total Pages: 446

ISBN-13: 0429942001

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Spectral, Photon Counting Computed Tomography is a comprehensive cover of the latest developments in the most prevalent imaging modality (x-ray computed tomography (CT)) in its latest incarnation: Spectral, Dual-Energy, and Photon Counting CT. Disadvantages of the conventional single-energy technique used by CT technology are that different materials cannot be distinguished and that the noise is larger. To address these problems, a novel spectral CT concept has been proposed. Spectral Dual-Energy CT (DE-CT) acquires two sets of spectral data, and Spectral Photon Counting CT (PC-CT) detects energy of x-ray photons to reveal additional material information of objects by using novel energy-sensitive, photon-counting detectors. The K-edge imaging may be a gateway for functional or molecular CT. The book covers detectors and electronics, image reconstruction methods, image quality assessments, a simulation tool, nanoparticle contrast agents, and clinical applications for spectral CT.


Spectral Computed Tomography

Spectral Computed Tomography

Author: Björn J. Heismann

Publisher: SPIE-International Society for Optical Engineering

Published: 2012

Total Pages: 0

ISBN-13: 9780819492579

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Computed tomography (CT) is a widely used x-ray scanning technique. In its prominent use as a medical imaging device, CT serves as a workhorse in many clinical settings throughout the world. It provides answers to urgent diagnostic tasks such as oncology tumor staging, acute stroke analysis, or radiation therapy planning. Spectral Computed Tomography provides a concise, practical coverage of this important medical tool. The first chapter considers the main clinical motivations for spectral CT applications. In Chapter 2, the measurement properties of spectral CT systems are described. Chapter 3 provides an overview of the current state of research on spectral CT algorithms. Based on this overview, the technical realization of spectral CT systems is evaluated in Chapter 4. Device approaches such as DSCT, kV switching, and energy-resolving detectors are compared. Finally, Chapter 5 summarizes various algorithms for spectral CT reconstructions and spectral CT image postprocessing, and links these algorithms to clinical use cases


Photon Counting Computed Tomography

Photon Counting Computed Tomography

Author: Scott Hsieh

Publisher: Springer Nature

Published: 2023-05-27

Total Pages: 271

ISBN-13: 3031260627

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This book will provide readers with a good overview of some of most recent advances in the field of Photon Counting CT technology for X-ray medical imaging, especially as it pertains to new detectors. There will be a good mixture of general chapters in both technology and applications in CT medical imaging. The book will have an in-depth review of the research topics from world-leading specialists in the field. The conversion of the X-ray signal into analogue/digital value will be covered in some chapters. The authors also provide a review of CMOS chips for X-ray image sensors, methods of material discrimination and image reconstruction techniques. Covers a broad range of topics, including an introduction to novel spectral Computed Tomography; Includes in-depth analysis on how to optimize X-ray detection; Discusses analysis of electronics for X-ray detection.


Radiation Detectors for Medical Imaging

Radiation Detectors for Medical Imaging

Author: Jan S. Iwanczyk

Publisher: CRC Press

Published: 2015-10-16

Total Pages: 331

ISBN-13: 149876682X

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Radiation Detectors for Medical Imaging discusses the current state of the art and future prospects of photon-counting detectors for medical imaging applications. Featuring contributions from leading experts and pioneers in their respective fields, this book:Describes x-ray spectral imaging detectors based on cadmium zinc telluride (CdZnTe) and cad


Solid-State Radiation Detectors

Solid-State Radiation Detectors

Author: Salah Awadalla

Publisher: CRC Press

Published: 2017-12-19

Total Pages: 318

ISBN-13: 1351830902

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Integrating aspects of engineering, application physics, and medical science, Solid-State Radiation Detectors: Technology and Applications offers a comprehensive review of new and emerging solid-state materials-based technologies for radiation detection. Each chapter is structured to address the current advantages and challenges of each material and technology presented, as well as to discuss novel research and applications. Featuring contributions from leading experts in industry and academia, this authoritative text: Covers modern semiconductors used for radiation monitoring Examines CdZnTe and CdTe technology for imaging applications including three-dimensional capability detectors Highlights interconnect technology for current pixel detectors Describes hybrid pixel detectors and their characterizations Tackles the integrated analog signal processing read-out front ends for particle detectors Considers new organic materials with direct bandgap for direct energy detection Summarizes recent developments involving lanthanum halide and cerium bromide scintillators Analyzes the potential of recent progress in the field of crystallogenesis, quantum dots, and photonics crystals toward a new concept of x- and gamma-ray detectors based on metamaterials Explores position-sensitivity photomultipliers and silicon photomultipliers for scintillation crystals Solid-State Radiation Detectors: Technology and Applications provides a valuable reference for engineers and scientists looking to enhance the performance of radiation detector technology for medical imaging and other applications.


Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach

Author: Kakoli Bose

Publisher: Springer Nature

Published: 2019-11-25

Total Pages: 587

ISBN-13: 9813298162

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Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.


Spectral Imaging

Spectral Imaging

Author: Hatem Alkadhi

Publisher: Springer Nature

Published: 2022-05-02

Total Pages: 375

ISBN-13: 3030962857

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This book, edited by leading experts in radiology, offers a state-of-the-art overview of the specifics and the added value of dual-energy, multi-energy, and spectral computed tomography (CT). Latest advances and upcoming innovations such as photon-counting detector CT are covered by renown experts in the field. The entire spectrum of clinical applications of dual-energy and spectral CT throughout the body is covered. Book chapters are written by expert authors with a background in physics and radiology and are richly illustrated with high quality figures, graphical illustrations, and tables. The first section covers background issues and the most relevant technical aspects of the technique, including a detailed description of the approaches to dual-energy, spectral and photon-counting CT by different vendors of CT scanners. The second part focusses on the use of dual-energy, spectral and photon-counting CT in daily clinical practice, and individual chapters are devoted to imaging of the brain, cardiovascular system, gastrointestinal tract, abdominal organs, skeletal system, and the chest. The focus of the book ensures that it will be of interest for a multidisciplinary forum of readers comprising radiologists, medical physicists, and other medical professionals and scientists being interested in cutting-edge CT imaging.


Imaging in Dermatology

Imaging in Dermatology

Author: Michael R. Hamblin

Publisher: Academic Press

Published: 2016-07-29

Total Pages: 562

ISBN-13: 0128028599

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Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and molecular effects of these technologies. - Outlines the fundamentals of imaging and lasers for dermatology in clinical and research settings - Provides knowledge of current and future applications of dermatological imaging and lasers - Coherently structured book written by the experts working in the fields covered


Emerging Imaging Technologies in Medicine

Emerging Imaging Technologies in Medicine

Author: Mark A. Anastasio

Publisher: CRC Press

Published: 2012-12-06

Total Pages: 365

ISBN-13: 1439880417

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From the discovery of x-rays in 1895 through the emergence of computed tomography (CT) in the 1970s and magnetic resonance imaging (MRI) in the 1980s, non-invasive imaging has revolutionized the practice of medicine. While these technologies have thoroughly penetrated clinical practice, scientists continue to develop novel approaches that promise to push imaging into entirely new clinical realms, while addressing the issues of dose, sensitivity, or specificity that limit existing imaging approaches. Emerging Imaging Technologies in Medicine surveys a number of emerging technologies that have the promise to find routine clinical use in the near- (less than five years), mid- (five to ten years) and long-term (more than ten years) time frames. Each chapter provides a detailed discussion of the associated physics and technology, and addresses improvements in terms of dose, sensitivity, and specificity, which are limitations of current imaging approaches. In particular, the book focuses on modalities with clinical potential rather than those likely to have an impact mainly in preclinical animal imaging. The last ten years have been a period of fervent creativity and progress in imaging technology, with improvements in computational power, nanofabrication, and laser and detector technology leading to major new developments in phase-contrast imaging, photoacoustic imaging, and optical imaging.


Dual Energy CT in Clinical Practice

Dual Energy CT in Clinical Practice

Author: Thorsten Johnson

Publisher: Springer Science & Business Media

Published: 2011-01-18

Total Pages: 209

ISBN-13: 3642017401

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Dual-energy CT is a novel, rapidly emerging imaging technique which offers important new functional and specific information. In this book, physicists and specialists from different CT manufacturers provide an insight into the technological basis of, and the different approaches to, dual-energy CT. Renowned medical scientists in the field explain the pathophysiological and molecular background of the technique, discuss its applications, provide detailed advice on how to obtain optimal results, and offer hints regarding clinical interpretation. The main focus is on the use of dual-energy CT in daily clinical practice, and individual sections are devoted to imaging of the vascular system, the thorax, the abdomen, and the extremities. Evaluations and recommendations are based on personal experience and peer-reviewed literature. Plenty of carefully chosen high-quality images are included to illustrate the clinical benefits of the technique.