Molecular Nutrition and Diabetes
Molecular Nutrition and Diabetes

Author: Didac Mauricio

Publisher: Academic Press

Published: 2015-12-08

Total Pages: 400

ISBN-13: 0128017619

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Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control. Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes. - Offers updated information and a perspective on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of diabetes mellitus - Explores how nutritional factors are involved in the pathogenesis of both type1 and type2 diabetes and their complications - Investigates the molecular and genetic bases of diabetes and diabetic metabolism through the lens of a rapidly evolving field of molecular nutrition

Molecular Nutrition
Molecular Nutrition

Author: Vinood B. Patel

Publisher: Academic Press

Published: 2019-08-24

Total Pages: 793

ISBN-13: 0128119365

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Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book. - Summarizes molecular nutrition in health as related to vitamins - Includes material on signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis - Presents transcriptional processes, homeostasis genes, cancer, gene expression, mutations, the sodium-dependent multivitamin transporter, p53, p21, microRNAs, one carbon metabolism, nucleic acids, DNA methylation and polymorphisms - Addresses emerging fields of molecular biology and presents important discoveries related to diet and nutritional health - Covers Vitamins A, B, C, D, E, and K - Discusses their impact on health relating to cancer, diabetes, arthritis, and aging - Includes key facts, a mini dictionary of terms, and summary points

The Molecular Nutrition of Fats
The Molecular Nutrition of Fats

Author: Vinood Patel

Publisher: Academic Press

Published: 2018-10-29

Total Pages: 462

ISBN-13: 0128112980

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The Molecular Nutrition of Fats presents the nutritional and molecular aspects of fats by assessing their dietary components, their structural and metabolic effects on the cell, and their role in health and disease. Subject areas include molecular mechanisms, membranes, polymorphisms, SNPs, genomic wide analysis, genotypes, gene expression, genetic modifications and other aspects. The book is divided into three sections, providing information on the general and introductory aspects, the molecular biology of the cell, and the genetic machinery and its function. Topics discussed include lipid-related molecules, dietary lipids and lipid metabolism, high fat diets, choline, cholesterol, membranes, trans-and saturated fatty acids, and lipid rafts. Other sections provide comprehensive discussions on G protein-coupled receptors, micro RNA, transcriptomics, transcriptional factors, cholesterol, triacylglycerols, beta-oxidation, cholesteryl ester transfer, beta-oxidation, lysosomes, lipid droplets, insulin mTOR signaling and ligands, and more. - Summarizes molecular nutrition in health as related to fats - Discusses the impact of fats on cancer, heart disease, dementia, and respiratory and intestinal disease - Includes preclinical, clinical and population studies - Covers the genome, the whole body and whole communities - Includes key facts, a mini dictionary of terms and summary points

Molecular Nutrition: Carbohydrates
Molecular Nutrition: Carbohydrates

Author: Vinood B. Patel

Publisher: Academic Press

Published: 2019-10-16

Total Pages: 444

ISBN-13: 0128498749

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Molecular Nutrition: Carbohydrates presents the nutritional and molecular aspects of carbohydrates. As part of the Molecular Nutrition includes sections covering carbohydrate metabolism, carbohydrates in the diet, insulin resistance, dietary sugars, cardiometabolic risk, lipoproteins, low-carbohydrate diets, antioxidants, refined dietary sugars, fats, glucose transporters, glucose sensing, the role of phosphorylation, carbohydrate responsive binding protein, cyclic AMP, peroxisome proliferator-activated receptors, SIRT1, insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes rRNA and transcription, and more. In addition, the book addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health. - Summarizes molecular nutrition in health as related to carbohydrates - Addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health - Includes key facts, a mini dictionary of terms and summary points

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome
Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Author: Debasis Bagchi

Publisher: Academic Press

Published: 2012-01-31

Total Pages: 553

ISBN-13: 0123850835

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Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes Presents both prevention and treatment options

Diabetes
Diabetes

Author: Victor R Preedy

Publisher: Academic Press

Published: 2020-04-24

Total Pages: 456

ISBN-13: 0128157771

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Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer. - Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of diabetes and oxidation issues - Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet, its food matrix or plant - Includes preclinical, clinical and population studies to help endocrinologists, diabetologists, nutritionists, dieticians and clinicians map out key areas for research and further clinical recommendations

Molecular Nutrition
Molecular Nutrition

Author: Manlio Vinciguerra

Publisher: Academic Press

Published: 2020-10-15

Total Pages: 452

ISBN-13: 0128138637

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Molecular Nutrition: Mother and Infant presents the impact of diet in early life stages, from pre-conception, throughout pregnancy, and to the infant. The book covers the molecular biology of the cell, genetic machinery and its function, general coverage on diet and nutrition, pregnancy, placenta, weight gain, breast milk, feeding practices, gestational disease, glucose metabolism, immunity, vitamins and minerals. Other topics discusses include fetal programming, bioactive compounds, amino acids, intrauterine growth, one carbon metabolism, overnutrition, genetic risk factors, polymorphisms, folic acid genes, DNA methylation, genes involved in lipid metabolism, microRNAs, epigenetics, transcriptomics and micro RNA. This book will be a welcomed reference for research scientists and practitioners, including nutritionists and dieticians. - Addresses mother and infant nutrition and its critical impact on the well-being of humankind - Contains coverage from pre-conception to young offspring - Includes pedagogical features (e.g. a list of key facts, mini-dictionaries of terms and definitions, and summary points) to assist in its use as a reference - Contains coverage of emerging fields of molecular biology and important discoveries related to diet and nutritional health

Nutritional Strategies for the Diabetic/Prediabetic Patient
Nutritional Strategies for the Diabetic/Prediabetic Patient

Author: Jeffrey I. Mechanick

Publisher: CRC Press

Published: 2006-01-27

Total Pages: 366

ISBN-13: 1420014889

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While nutrition is central to the management of diabetes, there is no onediabetic diet. Nutritional prescriptions depend on the type of diabetes, food preferences, lifestyle, treatment regimen, comorbidities, state of health, and the route of caloric administration. Nutritional Strategies for the Diabetic/Prediabetic Patient is a comprehensive r

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases
Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Author: Solomon Habtemariam

Publisher: Academic Press

Published: 2019-06-08

Total Pages: 1182

ISBN-13: 0081029233

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Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. - Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level - Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases - Examines the pharmacological findings on medicinal foods, including available clinical trials