Molecular, Clinical and Environmental Toxicology
Molecular, Clinical and Environmental Toxicology

Author: Andreas Luch

Publisher: Springer Science & Business Media

Published: 2009-04-03

Total Pages: 479

ISBN-13: 3764383364

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Molecular Toxicology is the first volume of a three-volume set Molecular, Clinical and Environmental Toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, this work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health and engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Molecular Aspects of Oxidative Drug Metabolizing Enzymes
Molecular Aspects of Oxidative Drug Metabolizing Enzymes

Author: Emel Arinc

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 615

ISBN-13: 3642795285

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Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published: 1992

Total Pages: 690

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.

Cytochrome P450
Cytochrome P450

Author: John B. Schenkman

Publisher: Springer Science & Business Media

Published: 2013-03-08

Total Pages: 740

ISBN-13: 3642777635

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The most complete and up-to-date survey of this important superfamily of enzymes, including the first ever coverage of the forms involved in steroid hormone biosynthesis. The components of the enzyme system, the reaction mechanisms involved, and the evolution and nomenclature are analyzed, as is the hepatic microsomal enzyme in a large number of species, illustrating the very wide implications for life processes.

Introduction to Drug Metabolism
Introduction to Drug Metabolism

Author: G. GORDON GIBSON AND PAUL SKETT

Publisher: Springer

Published: 2013-12-11

Total Pages: 275

ISBN-13: 148996844X

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This introduction to the mechanisms by which the body metabolizes and excretes administered drugs is directed at advanced undergraduate biochemists, pharmacologists, pre-clinical medical students and advanced undergraduate/postgraduate toxicologists.