Molecular and Phenomenological Characterization of Synaptic Homeostasis at the Drosophila Neuromuscular Junction
Author: Kurt W. Marek
Publisher:
Published: 2004
Total Pages: 396
ISBN-13:
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Author: Kurt W. Marek
Publisher:
Published: 2004
Total Pages: 396
ISBN-13:
DOWNLOAD EBOOKAuthor: Lindsay A. Gray
Publisher:
Published: 2016
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: Stephanie D. Albin
Publisher:
Published: 2006
Total Pages: 298
ISBN-13:
DOWNLOAD EBOOKThe molecular mechanisms underlying the retrograde control of presynaptic neurotransmitter release at the NMJ are not well understood. Here we describe the identification of the first known inhibitor of synaptic homeostasis. Identification of the pathways through which this inhibitor act may eventually lead to a greater understanding of the mechanisms that regulate homeostasis.
Author: Hong Iris Wan
Publisher:
Published: 2000
Total Pages: 392
ISBN-13:
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Publisher:
Published: 2004
Total Pages: 740
ISBN-13:
DOWNLOAD EBOOKAuthor: Hans-Peter Landolt
Publisher: Springer Nature
Published: 2019-09-03
Total Pages: 481
ISBN-13: 3030112721
DOWNLOAD EBOOKThis volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions. The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com
Author: Uri Alon
Publisher: CRC Press
Published: 2019-07-12
Total Pages: 324
ISBN-13: 1000001326
DOWNLOAD EBOOKPraise for the first edition: ... superb, beautifully written and organized work that takes an engineering approach to systems biology. Alon provides nicely written appendices to explain the basic mathematical and biological concepts clearly and succinctly without interfering with the main text. He starts with a mathematical description of transcriptional activation and then describes some basic transcription-network motifs (patterns) that can be combined to form larger networks. – Nature [This text deserves] serious attention from any quantitative scientist who hopes to learn about modern biology ... It assumes no prior knowledge of or even interest in biology ... One final aspect that must be mentioned is the wonderful set of exercises that accompany each chapter. ... Alon’s book should become a standard part of the training of graduate students. – Physics Today Written for students and researchers, the second edition of this best-selling textbook continues to offer a clear presentation of design principles that govern the structure and behavior of biological systems. It highlights simple, recurring circuit elements that make up the regulation of cells and tissues. Rigorously classroom-tested, this edition includes new chapters on exciting advances made in the last decade. Features: Includes seven new chapters The new edition has 189 exercises, the previous edition had 66 Offers new examples relevant to human physiology and disease
Author: Scott L. Hooper
Publisher: John Wiley & Sons
Published: 2017-09-05
Total Pages: 510
ISBN-13: 1118873408
DOWNLOAD EBOOKA multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.
Author: Ajit Varki
Publisher: CSHL Press
Published: 1999
Total Pages: 694
ISBN-13: 9780879696818
DOWNLOAD EBOOKSugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author: Ole P. Ottersen
Publisher:
Published: 1990-09-13
Total Pages: 516
ISBN-13:
DOWNLOAD EBOOKThis dynamic field of research offers the exciting possibility for a better understanding of brain function. Presented here is an up-to-date review of the recent advances in basic research in the field. Topics covered include: the discovery of the neurotransmitter role of glycine; patch-clamp studies of glycine-gated chloride channels; the involvement of glycine in excitatory neurotransmission; antibodies and fixatives for the immunocytochemical localization of glycine; the anatomy, development, physiology and role of glycinergic neurons in the Xenopus embryo spinal cord; and immunocytochemistry of glycine and glycine receptors in the central auditory system.