Voltage Gated Sodium Channels
Voltage Gated Sodium Channels

Author: Peter C. Ruben

Publisher: Springer Science & Business Media

Published: 2014-04-15

Total Pages: 328

ISBN-13: 3642415881

DOWNLOAD EBOOK

A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Molecular Action of Insecticides on Ion Channels
Molecular Action of Insecticides on Ion Channels

Author: John Marshall Clark

Publisher:

Published: 1995

Total Pages: 376

ISBN-13:

DOWNLOAD EBOOK

Documents ongoing research into the molecular understanding of insecticide action, including the action of insecticides on major ion channel families, voltage-sensitive channels, ligand-gated channels, and biopesticide-induced channels. Presents recent advances in how researchers envision molecular binding sites of insecticides on ion channels and the molecular alterations of these sites resulting in site-insensitive resistance mechanisms. Describes new receptor-ion channels and mosaic receptor organizations as novel sites of insecticide action.

Biochemical Sites of Insecticide Action and Resistance
Biochemical Sites of Insecticide Action and Resistance

Author: Isaac Ishaaya

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 353

ISBN-13: 3642595499

DOWNLOAD EBOOK

In recent years many of the conventional methods of insect control by broad spectrum synthetic chemicals have come under scrutiny because of their unde sirable effects on human health and the environment. In addition, some classes of pesticide chemistry, which generated resistance problems and severely affected the environment, are no longer used. It is against this background that the authors of this book present up-to-date findings-relating to biochemical sites that can serve as targets for developing insecticides with selective prop erties, and as the basis for the elucidation of resistance mechanisms and countermeasures. The book consists of eight chapters relating to biochemical targets for insec ticide action and seven chapters relating to biochemical modes of resistance and countermeasures. The authors of the chapters are world leaders in pesti cide chemistry, biochemical modes of action and mechanisms of resistance. Biochemical sites such as chitin formation, juvenile hormone and ecdysone receptors, acetylcholine and GABA receptors, ion channels, and neuropeptides are potential targets for insecticide action. The progress made in recent years in molecular biology (presented in depth in this volume) has led to the iden tification of genes that confer mechanisms of resistance, such as increased detoxification, decreased penetration and insensitive target sites. A combina tion of factors can lead to potentiation of the resistance level. Classifications of these mechanisms are termed gene amplification, changes in structural genes, and modification of gene expression.

Insect Nicotinic Acetylcholine Receptors
Insect Nicotinic Acetylcholine Receptors

Author: Steeve Hervé Thany

Publisher: Springer Science & Business Media

Published: 2011-01-11

Total Pages: 127

ISBN-13: 1441964452

DOWNLOAD EBOOK

The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out some of the future challenges. For example, we need to determine the precise subunit nomenclature of insect nicotinic receptors. This nomenclature varies amongst species and this led to some of the early confusion that persists. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.

Neurotoxicity of Pesticides
Neurotoxicity of Pesticides

Author:

Publisher: Academic Press

Published: 2020-03-21

Total Pages: 288

ISBN-13: 0128205156

DOWNLOAD EBOOK

Neurotoxicity of Pesticides, Volume Four, in this comprehensive serial addresses contemporary advances in neurotoxicology of pesticides by providing authoritative review articles on key issues in the field. Edited by leading subject experts, topics of note in this new release include Organophosphates, OPs, Nerve agents, Pyrethroids, Neonicotinoids and Formamidines, among others.

Modern Crop Protection Compounds
Modern Crop Protection Compounds

Author: Peter Jeschke

Publisher: John Wiley & Sons

Published: 2019-05-06

Total Pages: 1772

ISBN-13: 3527340890

DOWNLOAD EBOOK

The leading reference on this topic has just gotten better. Building on the success of the previous two editions, all the chapters have been updated to reflect the latest developments in the field, and new chapters have been added on picolinic acids, oxathiapiprolin, flupyradifurone, and other topics. This third edition presents the most important active ingredients of modern agrochemicals, with one volume each for herbicides, fungicides, and insecticides. The international team of first-class authors from such renowned crop science companies as Bayer, Syngenta, Dow AgroSciences, DuPont (now Corteva Agriscience), and BASF, address all crucial aspects from the general chemistry and the mode of action to industrial-scale synthesis, as well as from the development of products and formulations to their application in the field. A comprehensive and invaluable source of timely information for all of those working in modern biology, including genetics, biochemistry and chemistry, and for those in modern crop protection science, whether governmental authorities, researchers in agrochemical companies, scientists at universities, conservationists, or managers in organizations and companies involved in improvements to agricultural production.

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

Author: Wolfgang B. Liedtke, MD, PH.D.

Publisher: CRC Press

Published: 2006-09-29

Total Pages: 502

ISBN-13: 1420005847

DOWNLOAD EBOOK

Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Insect Control
Insect Control

Author: Lawrence I. Gilbert

Publisher: Academic Press

Published: 2010-05-28

Total Pages: 481

ISBN-13: 0123814502

DOWNLOAD EBOOK

The publication of the extensive 7-volume work Comprehensive Molecular Insect Science provided library customers and their end-users with a complete reference encompassing important developments and achievements in modern insect science, including reviews on the ecdysone receptor, lipocalins, and bacterial toxins. One of the most popular areas in entomology is control, and this derivative work, Insect Control, taps into a previously unapproached market – the end user who desires to purchase a comprehensive yet affordable work on important aspects of this topic. Contents will include timeless articles covering insect growth- and development-disrupting insecticides, mechanisms and use of Bacillus thuringiensis, biology and genomics of polydnaviruses, pheromones: function and use in insect control, and more. New summaries for each chapter will give an overview of developments in the related article since its original publication. - Articles selected by the known and respected editor-in-chief and co-editor of the original MRW - The articles are classic reviews offering broad coverage of essential topics in insect control, with special addenda including author notes on the chapter since its original publication - Introduction by the editors puts the selected body of work in context for this volume, highlighting the need for entomologists and related researchers to have these reviews in their personal collection

Insecticides with Novel Modes of Action
Insecticides with Novel Modes of Action

Author: Isaac Ishaaya

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 442

ISBN-13: 3662035650

DOWNLOAD EBOOK

The future of insect control looked very bright in the 1950s and 1960s with new insecticides constantly coming onto the market. Today, however, whole classes of pesticide chemistry have fallen by the wayside due to misuse which generated resistance problems reaching crisis proportions, severe adverse effects on the environment, and public outcry that has led to increasingly stricter regulation and legislation. It is with this background, demanding the need for safer, environmentally friendly pesticides and new strategies to reduce resistance problems, that this book was written. The authors of the various chapters have a wealth of experience in pesticide chemistry, biochemical modes of action, mechanism of resistance and application, and have presented concise reviews. Each is actively involved in thedevelopment of new groups of pesticide chemistry which led to the development of novel insecticides with special impact in controlling agricultural pests. Emphasis has been given to insecticides with selective properties, such as insect growth regulators hormone mimics, ecdysone agonists), (chitin synthesis inhibitors, juvenile chloronicotinyl insecticides (imidacloprid, acetamiprid), botanical insecticides (neem, plant oils), pymetrozine, diafenthiuron, pyrrole insecticides, and others. The importance of these compounds, as components in integrated pest management programs and in insecticide resistance management strategies, is discussed. The data presented are essential in establishing new technologies and developing novel groups of compounds which will have impact on our future agricultural practices.

The Toxicology and Biochemistry of Insecticides
The Toxicology and Biochemistry of Insecticides

Author: Simon J. Yu

Publisher: CRC Press

Published: 2011-03-05

Total Pages: 294

ISBN-13: 1420059769

DOWNLOAD EBOOK

The first book in two decades to address this multi-faceted field, The Toxicology and Biochemistry of Insecticides provides the most up-to-date information on insecticide classification, formulation, mode of action, resistance, metabolism, environmental fate, and regulatory legislation. The book draws on the author's groundbreaking research