Precision Psychiatry

Precision Psychiatry

Author: Leanne M. Williams, Ph.D.

Publisher: American Psychiatric Pub

Published: 2021-10-15

Total Pages: 302

ISBN-13: 1615371583

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Precision psychiatry, as outlined in this groundbreaking book, presents a new path forward. By integrating findings from basic and clinical neuroscience, clinical practice, and population-level data, the field seeks to develop therapeutic approaches tailored for specific individuals with a specific constellation of health issues, characteristics, strengths, and symptoms.


Statistical Methods in Psychiatry Research and SPSS

Statistical Methods in Psychiatry Research and SPSS

Author: M. Venkataswamy Reddy

Publisher: CRC Press

Published: 2014-11-03

Total Pages: 353

ISBN-13: 177188035X

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This book has been prepared to help psychiatrists expand their knowledge of statistical methods and fills the gaps in their applications as well as introduces data analysis software. The book emphasizes the classification of fundamental statistical methods in psychiatry research that are precise and simple. Professionals in the field of mental health and allied subjects without any mathematical background can easily understand all the relevant statistical methods and carry out the analysis and interpret the results in their respective fields without consulting a statistician. The sequence of the chapters, the sections within the chapters, the subsections within the sections, and the points within the subsections have all been arranged to help professionals in classification refine their knowledge in statistical methods and fill the gaps, if any. Emphasizing simplicity, the fundamental statistical methods are demonstrated by means of arithmetical examples that may be reworked with pencil and paper in a matter of minutes. The results of the rework have to be checked by using SPSS, and in this way professionals are introduced to this psychiatrist-friendly data analysis software. Topics covered include: • An overview of psychiatry research • The organization and collection of data • Descriptive statistics • The basis of statistical inference • Tests of significance • Correlational data analysis • Multivariate data analysis • Meta-analysis • Reporting the results • Statistical software The language of the book is very simple and covers all aspects of statistical methods starting from organization and collection of data to descriptive statistics, statistical inference, multivariate analysis, and meta-analysis. Two chapters on computer applications deal with the most popular data analysis software: SPSS. The book will be very valuable to professionals and post-graduate students in psychiatry and allied fields, such as psychiatric social work, clinical psychology, psychiatric nursing, and mental health education and administration.


Research Training in Psychiatry Residency

Research Training in Psychiatry Residency

Author: Committee on Incorporating Research into Psychiatry Residency Training.

Publisher: National Academies Press

Published: 2003-12-23

Total Pages: 270

ISBN-13: 0309166896

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The number of psychiatric researchers does not seem to be keeping pace with the needs and opportunities that exist in brain and behavioral medicine. An Institute of Medicine committee conducted a broad review of the state of patient-oriented research training in the context of the psychiatry residency and considered the obstacles to such training and strategies for overcoming those obstacles. Careful consideration was given to the demands of clinical training. The committee concluded that barriers to research training span three categories: regulatory, institutional, and personal factors. Recommendations to address these issues are presented in the committee’s report, including calling for research literacy requirements and research training curricula tailored to psychiatry residency programs of various sizes. The roles of senior investigators and departmental leadership are emphasized in the report, as is the importance of longitudinal training (e.g., from medical school through residency and fellowship). As there appears to be great interest among numerous stakeholders and a need for better tracking data, an overarching recommendation calls for the establishment of a national body to coordinate and evaluate the progress of research training in psychiatry.


The Medical Model in Mental Health

The Medical Model in Mental Health

Author: Ahmed Samei Huda

Publisher: Oxford University Press

Published: 2019-05-16

Total Pages: 417

ISBN-13: 0192534092

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Many published books that comment on the medical model have been written by doctors, who assume that readers have the same knowledge of medicine, or by those who have attempted to discredit and attack the medical practice. Both types of book have tended to present diagnostic categories in medicine as universally scientifically valid examples of clear-cut diseases easily distinguished from each other and from health; with a fixed prognosis; and with a well-understood aetiology leading to disease-reversing treatments. These are contrasted with psychiatric diagnoses and treatments, which are described as unclear and inadequate in comparison. The Medical Model in Mental Health: An Explanation and Evaluation explores the overlap between the usefulness of diagnostic constructs (which enable prognosis and treatment decisions) and the therapeutic effectiveness of psychiatry compared with general medicine. The book explains the medical model and how it applies in mental health, assuming little knowledge or experience of medicine, and defends psychiatry as a medical practice.


Personalized Psychiatry

Personalized Psychiatry

Author: Bernhard Baune

Publisher: Academic Press

Published: 2019-10-16

Total Pages: 594

ISBN-13: 0128131772

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Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective


Proteomic Methods in Neuropsychiatric Research

Proteomic Methods in Neuropsychiatric Research

Author: Paul C. Guest

Publisher: Springer

Published: 2017-03-28

Total Pages: 362

ISBN-13: 3319524798

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Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.


Computational Psychiatry

Computational Psychiatry

Author: Peggy Series

Publisher: MIT Press

Published: 2020-11-24

Total Pages: 344

ISBN-13: 0262360713

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The first introductory textbook in the emerging, fast-developing field of computational psychiatry. Computational psychiatry applies computational modeling and theoretical approaches to psychiatric questions, focusing on building mathematical models of neural or cognitive phenomena relevant to psychiatric diseases. It is a young and rapidly growing field, drawing on concepts from psychiatry, psychology, computer science, neuroscience, electrical and chemical engineering, mathematics, and physics. This book, accessible to nonspecialists, offers the first introductory textbook in computational psychiatry.


Handbook of Research Methods for Studying Daily Life

Handbook of Research Methods for Studying Daily Life

Author: Matthias R. Mehl

Publisher: Guilford Publications

Published: 2013-10-01

Total Pages: 705

ISBN-13: 1462513050

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Bringing together leading authorities, this unique handbook reviews the breadth of current approaches for studying how people think, feel, and behave in everyday environments, rather than in the laboratory. The volume thoroughly describes experience sampling methods, diary methods, physiological measures, and other self-report and non-self-report tools that allow for repeated, real-time measurement in natural settings. Practical guidance is provided to help the reader design a high-quality study, select and implement appropriate methods, and analyze the resulting data using cutting-edge statistical techniques. Applications across a wide range of psychological subfields and research areas are discussed in detail.


The Biopsychosocial Model of Health and Disease

The Biopsychosocial Model of Health and Disease

Author: Derek Bolton

Publisher: Springer

Published: 2019-03-28

Total Pages: 157

ISBN-13: 3030118991

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This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.