Manual of Blood Platelets: Morphology, Physiology and Pharmacology

Manual of Blood Platelets: Morphology, Physiology and Pharmacology

Author: Gundu HR Rao

Publisher: Jaypee Brothers Medical Publishers

Published: 2018-11-30

Total Pages: 283

ISBN-13: 9352702026

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Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The book concludes with chapters on acute coronary problems, interaction between endothelial cells and platelets, and blood biocompatibility studies. Authored by a Minneapolis-based expert in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to blood platelets for haematologists Extensive coverage of antiplatelet drugs and resistance Recognised author from University of Minnesota Highly illustrated with clinical photographs, diagrams and tables


Williams Hematology, 9E

Williams Hematology, 9E

Author: Kenneth Kaushansky

Publisher: McGraw Hill Professional

Published: 2015-12-23

Total Pages: 2528

ISBN-13: 0071833013

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Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.


Cardiometabolic Diseases

Cardiometabolic Diseases

Author: Gundu H. R. Rao

Publisher: Elsevier

Published: 2024-09-27

Total Pages: 566

ISBN-13: 0323954715

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Cardiometabolic diseases are a group of metabolic dysfunctions mainly characterized by insulin resistance, impaired glucose tolerance, dyslipidemia, hypertension, and central adiposity that are major contributors to increased risk of acute vascular events such as myocardial infarction, heart failure and stroke. Cardiometabolic Diseases: Molecular Basis, Early Detection of Risks, and Management provides detailed information on all aspects of metabolic dysfunctions and associated risks for cardiometabolic diseases, including a thoughtful discussion of cellular and molecular mechanisms involved in the progression of metabolic risks, the approaches for the early detection and robust management of metabolic risks. Written by a team of expert contributors, this book is useful reading for researchers and clinicians interested on recent advances in etiology of cardiometabolic diseases, the latest noninvasive approaches for diagnosis, risk assessment tools, therapeutic strategies, and also aspects of prevention of cardiometabolic diseases. - Covers all aspects of cardiometabolic diseases, from cellular and molecular mechanisms involved in the development of metabolic risks to clinical practice - Provides established guidelines that facilitate effective management of the independent risk factors that promote vascular diseases - Discusses the use of diagnostic tools to empower patients to self-monitor the progress or regress of modifiable risks


Williams Hematology, 10th Edition

Williams Hematology, 10th Edition

Author: Kenneth Kaushansky

Publisher: McGraw Hill Professional

Published: 2021-01-14

Total Pages: 2705

ISBN-13: 126046413X

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The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everything that has made Williams Hematology the go-to resource for decades and has been updated with new chapters and critical new research into the molecular mechanisms responsible for hematological disorders and the impact on diagnosis and treatment. And the new format enables you to access each chapter via content modules covering key topics, with summaries, infographics, and cases―all linked to review questions for self-assessment. The full-color presentation integrates images of blood and tissue findings where they are cited in the text. NEW TO THIS EDITION: Updated and revised content reflecting the latest research and developments Convenient format that streamlines the learning process and improves retention Additional chapters added on: Immune Checkpoint Inhibitors Immune Cell Therapy: Chimeric Antigen Receptor T Cell Therapy Immune Cell Therapy Dendritic Cell and Natural Killer Cell Therapy The processes of cell death and survival Application of Big Data and Deep Learning in Hematology Williams Hematology Cases with multiple-choice questions including detailed explanations—perfect preparation for the boards Continuously updated online content with comprehensive drug therapy database and other resources


Clinical Hematology Atlas

Clinical Hematology Atlas

Author: Jacqueline H. Carr

Publisher: Elsevier Health Sciences

Published: 2009

Total Pages: 280

ISBN-13: 1416050396

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Previous ed.: Saint Louis, Mo.: Elsevier Saunders, 2004.


Concepts and Principles of Pharmacology

Concepts and Principles of Pharmacology

Author: James E. Barrett

Publisher: Springer Nature

Published: 2019-12-24

Total Pages: 457

ISBN-13: 3030353621

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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.


Pathophysiology of Blood Disorders

Pathophysiology of Blood Disorders

Author: Howard Franklin Bunn

Publisher: McGraw Hill Professional

Published: 2010-12-27

Total Pages: 354

ISBN-13: 0071713786

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A concise full-color review of the mechanisms of blood diseases and disorders – based on a Harvard Medical School hematology course 4 STAR DOODY'S REVIEW! "This is a superb book. Deceptively small, yet packs a wallop. The emphasis on principles instead of practice is welcome....The text is clear, concise, and surprisingly approachable for what could have been a very dense and dry discussion. I could not put this book down and read it entirely in one sitting. When was the last time anyone found a hematology textbook so riveting?"--Doody's Review Service Hematological Pathophysiology is a well-illustrated, easy-to-absorb introduction to the physiological principles underlying the regulation and function of blood cells and hemostasis, as well as the pathophysiologic mechanisms responsible for the development of blood disorders. Featuring a strong emphasis on key principles, the book covers diagnosis and management primarily within a framework of pathogenesis. Authored by world-renowned clinician/educators at Harvard Medical School, Hematological Pathophysiology features content and organization based on a hematology course offered to second year students at that school. The book is logically divided into four sections: Anemias and Disorders of the Red Blood Cell, Disorders of Hemostasis and Thrombosis, Disorders of Leukocytes, and Transfusion Medicine; it opens with an important overview of blood and hematopoietic tissues. Features Succinct, to-the-point coverage that reflects current medical education More than 200 full-color photographs and renderings of disease mechanisms and blood diseases Each chapter includes learning objectives and self-assessment questions Numerous tables and diagrams encapsulate important information Incorporates the feedback of 180 Harvard medical students who reviewed the first draft -- so you know you’re studying the most relevant material possible


Cell Physiology Source Book

Cell Physiology Source Book

Author: Nicholas Sperelakis

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 1262

ISBN-13: 0080574556

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This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics