Tumor-Induced Immune Suppression
Tumor-Induced Immune Suppression

Author: Dmitry I. Gabrilovich

Publisher: Springer Science & Business Media

Published: 2014-02-10

Total Pages: 471

ISBN-13: 1489980563

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Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.

Advances in Brazing
Advances in Brazing

Author: Dušan P Sekulić

Publisher: Elsevier

Published: 2013-03-04

Total Pages: 625

ISBN-13: 0857096508

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Brazing processes offer enhanced control, adaptability and cost-efficiency in the joining of materials. Unsurprisingly, this has lead to great interest and investment in the area. Drawing on important research in the field, Advances in brazing provides a clear guide to the principles, materials, methods and key applications of brazing. Part one introduces the fundamentals of brazing, including molten metal wetting processes, strength and margins of safety of brazed joints, and modeling of associated physical phenomena. Part two goes on to consider specific materials, such as super alloys, filler metals for high temperature brazing, diamonds and cubic boron nitride, and varied ceramics and intermetallics. The brazing of carbon-carbon (C/C) composites to metals is also explored before applications of brazing and brazed materials are discussed in part three. Brazing of cutting materials, use of coating techniques, and metal-nonmetal brazing for electrical, packaging and structural applications are reviewed, along with fluxless brazing, the use of glasses and glass ceramics for high temperature applications and nickel-based filler metals for components in contact with drinking water. With its distinguished editor and international team of expert contributors, Advances in brazing is a technical guide for any professionals requiring an understanding of brazing processes, and offers a deeper understanding of the subject to researchers and engineers within the field of joining. Reviews the advances of brazing processes in joining materials Discusses the fundamentals of brazing and considers specific materials, including super alloys, filler metals, ceramics and intermetallics Brazing of cutting materials and structural applications are also discussed

Advanced Heterogeneous Catalysts, Volume 1
Advanced Heterogeneous Catalysts, Volume 1

Author: Sudarsanam Putla

Publisher: ACS Symposium

Published: 2021-05-07

Total Pages: 608

ISBN-13: 9780841298804

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Advances and applications of nanosized catalysts Over the last five years, tremendous advances have been made in heterogeneous catalysis. In particular, catalysts' design from the bulk to nano-scale (1-100 nm), with desirable active sites, has received great attention in current catalysis research with the aim to fill the gap between homogeneous and heterogeneous catalysis. This volume focuses on applications of nanosized catalysts. Articles describe characterization, synthesis, and applications in biomass conversion, auto-exhaust purification, selective oxidation/hydrogenation, syngas conversion, and other important reactions. Readers will find examples of catalysts designed to be tunable for specific outcomes, inspiring their research. Scientists and engineers in chemistry, materials science, nanotechnology, and chemical engineering will find this volume useful.

High Temperature Electronics
High Temperature Electronics

Author: F. Patrick McCluskey

Publisher: CRC Press

Published: 1996-12-13

Total Pages: 354

ISBN-13: 9780849396236

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The development of electronics that can operate at high temperatures has been identified as a critical technology for the next century. Increasingly, engineers will be called upon to design avionics, automotive, and geophysical electronic systems requiring components and packaging reliable to 200 °C and beyond. Until now, however, they have had no single resource on high temperature electronics to assist them. Such a resource is critically needed, since the design and manufacture of electronic components have now made it possible to design electronic systems that will operate reliably above the traditional temperature limit of 125 °C. However, successful system development efforts hinge on a firm understanding of the fundamentals of semiconductor physics and device processing, materials selection, package design, and thermal management, together with a knowledge of the intended application environments. High Temperature Electronics brings together this essential information and presents it for the first time in a unified way. Packaging and device engineers and technologists will find this book required reading for its coverage of the techniques and tradeoffs involved in materials selection, design, and thermal management and for its presentation of best design practices using actual fielded systems as examples. In addition, professors and students will find this book suitable for graduate-level courses because of its detailed level of explanation and its coverage of fundamental scientific concepts. Experts from the field of high temperature electronics have contributed to nine chapters covering topics ranging from semiconductor device selection to testing and final assembly.

Stainless Steel 2000
Stainless Steel 2000

Author: Tom Bell

Publisher: CRC Press

Published: 2020-01-31

Total Pages: 428

ISBN-13: 100072493X

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Austenitic stainless steels lend themselves to a wide range of applications. However, they normally stiffer from poor wear resistance and do not respond well to traditional surface treatments. This volume. the fruit of a current status seminar, reflects the enormous strides which have been made in the last few years in the study of the expanded austenite phase (also called the S phase) and the development of new surface treatment techniques. As well as the papers presented at the seminar, the book contains selection from related papers and a comprehensive bibliography of the literature on the subject from 1979 to 2000.