Handbook of PAF and PAF Antagonists
Handbook of PAF and PAF Antagonists

Author: lPierre Braquet

Publisher: CRC Press

Published: 2019-06-13

Total Pages: 307

ISBN-13: 0429556446

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Published in 1991: Since its characterization in the 1970s from antigen-stimulated rabbit basophils, platelet-activating factor (PAF) has been demonstrated to be produced by, and act upon, a variety of cell types. PAF antagonists, which have been obtained from both natural sources and chemical synthesis, now represent a new class of therapeutic agents and may provide new prospects for treating several major pathologies, particularly shock, ischemia and asthma. This book provides a unique overview of the chemistry, molecular modeling, pharmacology, and clinical potential of the major classes of natural and synthetic PAF antagonists. Compounds reviewed include the ginkgolides, diketopiperazines, neolignans, hetrazepines, cyclic and 1,3-dioxolan derived PAF analogs, pyrrolo[1,2-c]thiazoles, imidazo[2,1-a]isoquinolines and pyridoquinazoline carboxamides. Consisting of 12 chapters written by leading experts in PAF antagonist research, this book is essential reading for students, researchers, clinicians, and medical practitioners involved in this rapidly developing field of biomedical research.

Handbook of Neurochemistry and Molecular Neurobiology
Handbook of Neurochemistry and Molecular Neurobiology

Author: Abel Lajtha

Publisher: Springer Science & Business Media

Published: 2009-10-27

Total Pages: 747

ISBN-13: 0387303456

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Contents include: 'Biochemistry and molecular biology of neural lipids', 'Advances in lipid analysis/lipidomics', 'Metabolism and enzymology of glycerolipids', 'Lipid metabolism in brain development and aging', 'Cellular and subcellular localization of neural lipids', and much more.

Handbook of Mediators in Septic Shock
Handbook of Mediators in Septic Shock

Author: Edmund A. Neugebauer

Publisher: CRC Press

Published: 2019-07-23

Total Pages: 610

ISBN-13: 1351079573

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Handbook of Mediators in Septic Shock presents a comprehensive, systematic evaluation of the various putative mediators of septic shock through the use of meta-analysis. Experts of individual mediators have objectively evaluated the collective literature using classical Koch-Dale Criteria for causal relationships. A decision tree approach has been used to analyze the existing evidence for each of the four Koch-Dale Criteria for each individual mediator of septic shock. The book provides an integrated perspective that describes how these many mediators interact. It also covers how advances in mathematical modeling of complex realities are applied to the field of septic shock pathogenesis. CRC Handbook of Mediators in Septic Shock will be a useful reference for emergency room and intensive care physicians, trauma specialists, pathophysiologists, physiologists, biochemists, pharmacologists, and others interested in the topic. Features

Handbook of Mucosal Immunology
Handbook of Mucosal Immunology

Author:

Publisher: Academic Press

Published: 2012-12-02

Total Pages: 791

ISBN-13: 0323138527

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Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae.The first section provides an introduction and historical perspective of the mucosal immune system and includes comprehensive discussion of the development and physiology of mucosal defense. It discusses such topics as the structure and function of themucosal epithelium, characteristics of mucosal-associated lymphoid tissue (MALT), Peyers patches, and concepts of mucosal vaccines. The second section focuses on the secretory immune system with special reference to mucosal diseases in the digestive (GALT), respiratory (BALT), and genitourinary tracts. This information is especially important in light of the current interest in the mechanisms, transmission, and prevention of infectious diseases such as AIDS, hepatitis, and tuberculosis.Virtually all chapters have been authored by the original investigators responsible for key observations on which current concepts are based. This handbook will be an invaluable resource for a diverse group of both researchers and practicing clinicians.Molecular biologists, immunologists, veterinarians, public health workers, physicians in specialties from pediatrics to pulmonology, and graduate students of mucosal immunology will all find this handbook the most complete work on the subject.

Handbook of Natural Toxins
Handbook of Natural Toxins

Author: Anthony Tu

Publisher: CRC Press

Published: 1991-02-28

Total Pages: 860

ISBN-13: 9780824783761

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In 24 contributed chapters, 37 international specialists describe the latest developments in research on snake venom including different types of venoms and toxins, actions, antidotes, and applications and summarize what is known to date on Gila monster and frog toxins. Some 70 tables provide essent

Handbook of Receptors and Channels
Handbook of Receptors and Channels

Author: Stephen J. Peroutka

Publisher: CRC Press

Published: 1993-10-20

Total Pages: 372

ISBN-13: 9780849383212

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The cloning, sequencing, and expression of a variety of membrane receptors and channels indicate the existence of at least four "superfamilies" of molecular structures that mediate signal transduction. Presently, more than 400 receptors have been cloned and sequenced. The Handbook of Receptors and Channels is the first handbook series to present the enormous amount of new molecular biological receptor data in a practical and useful format. Each volume in this remarkable series will focus on a specific molecular superfamily of receptors. Complete amino acid sequence information on all cloned receptors, as well as relevant pharmacological information, will be included. Furthermore, the format for each of the volumes will be consistent to allow for easy comparisons of different molecular subtypes for a given transmitter. G Protein-Coupled Receptors is the first volume in this new handbook series. Topics covered in future volumes include:

CRC Handbook of Organic Photochemistry and Photobiology, Third Edition - Two Volume Set
CRC Handbook of Organic Photochemistry and Photobiology, Third Edition - Two Volume Set

Author: Axel Griesbeck

Publisher: CRC Press

Published: 2019-04-05

Total Pages: 1607

ISBN-13: 1466561254

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The only combined organic photochemistry and photobiology handbookAs spectroscopic, synthetic and biological tools become more and more sophisticated, photochemistry and photobiology are merging-making interdisciplinary research essential. Following in the footsteps of its bestselling predecessors, the CRC Handbook of Organic Photochemistry and Pho

The Clinician's Handbook of Natural Medicine - E-Book
The Clinician's Handbook of Natural Medicine - E-Book

Author: Joseph E. Pizzorno

Publisher: Elsevier Health Sciences

Published: 2007-11-07

Total Pages: 833

ISBN-13: 1437725651

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Written by leading authorities in complementary and integrative medicine, this convenient, quick-reference handbook provides clear and rational directives on diagnosing and treating specific diseases and disorders with natural medicine. You'll get concise summaries of diagnostic procedures, general considerations, therapeutic considerations, and therapeutic approaches for 84 of the most commonly seen conditions, 12 of which are new to this edition, plus naturopathic treatment methods and easy-to-follow condition flowcharts. Based on Pizzorno's trusted Textbook of Natural Medicine and the most current evidence available, it's your key to accessing reliable, natural diagnosis and treatment options in any setting. - Expert authorship lends credibility to information. - Scientifically verified content assures the most reliable coverage of diagnostic and natural treatment methods. - Over 80 algorithms synthesize therapeutic content and provide support for your clinical judgment with a conceptual overview of case management. - The book's compact size makes it portable for easy reference in any setting. - A consistent organization saves you time and helps you make fast, accurate diagnoses. - 12 NEW chapters enhance your treatment knowledge and understanding with information on important and newly emerging treatments and areas of interest, including: - Cancer - Endometriosis - Fibromyalgia - Hair Loss in Women - Hyperventilation Syndrome - Infectious Diarrhea - Intestinal Protozoan Infestation - Lichen Planus - Parkinson's Disease - Porphyrias - Proctological Conditions - Uterine Fibroids - Each chapter is fully updated to reflect the content of the latest edition of Pizzorno's Textbook of Natural Medicine and keep you current on the safest and most effective natural interventions.