Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles

Author: Goutam Brahmachari

Publisher: Elsevier

Published: 2021-02-26

Total Pages: 642

ISBN-13: 0128205865

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Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability


Green Chemistry: Synthesis of Bioactive Heterocycles

Green Chemistry: Synthesis of Bioactive Heterocycles

Author: K. L. Ameta

Publisher: Springer

Published: 2014-06-17

Total Pages: 418

ISBN-13: 8132218507

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The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.


Modern Green Chemistry and Heterocyclic Compounds

Modern Green Chemistry and Heterocyclic Compounds

Author: Ravindra S. Shinde

Publisher: CRC Press

Published: 2020-03-31

Total Pages: 302

ISBN-13: 1000029174

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This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.


Lawesson’s Reagent in Heterocycle Synthesis

Lawesson’s Reagent in Heterocycle Synthesis

Author: Navjeet Kaur

Publisher: Springer Nature

Published: 2021-09-10

Total Pages: 307

ISBN-13: 9811646554

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This book focuses on the new and old methods for the synthesis of various heterocycles using Lawesson’s reagent. The book covers an important and rapidly growing branch of heterocyclic chemistry and can serve as a guide to those who are completing their education and are about to enter the job market. Students will be able to find all Lawesson’s reagent-assisted protocols for the synthesis of heterocycles in one place. This feature of the book provides an important benefit, because sometimes users want to see all the possibilities and relevant information for making a particular compound using one particular reagent. The purpose of this valuable resource is to provide the knowledge not only to students but also to pharmacologists, biochemists, organic and medicinal chemists, researchers, and academic professionals for easy access to synthetic protocols for different heterocycles using Lawesson’s reagent. The book will be greatly helpful for everyone involved in the field and can pave the way for better understanding and quantification of heterocycle synthesis.


Microwave-Induced Synthesis of Aromatic Heterocycles

Microwave-Induced Synthesis of Aromatic Heterocycles

Author: Abdul Rauf

Publisher: Springer Science & Business Media

Published: 2011-09-18

Total Pages: 98

ISBN-13: 9400714858

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For more than a century, heterocycles have played a crucial role in the biological and industrial development of society, becoming one of the most researched areas within organic chemistry. The first chapter of Microwave-Induced Synthesis of Aromatic Heterocycles is based on microwave theory, the latest developments in instrumentation technology, and the various microwave technologies used for synthesis. The remainder of the chapters are divided into two sections. Section A deals with the five-membered heterocycles (pyrazoles, isoxazoles, triazoles, oxadiazoles, thiazoles, imidazoles, oxazoles, oxazolines etc.) and in Section B, various six-membered heterocycles (triazines, benzoxazoles, benzimidazoles, benzothiazoles) are presented. Both sections contain a detailed, recent literature review of microwave assisted synthesis and its applicability to various aromatic heterocyclics.


Comprehensive Organic Chemistry Experiments for the Laboratory Classroom

Comprehensive Organic Chemistry Experiments for the Laboratory Classroom

Author: Carlos A. M. Afonso

Publisher: Royal Society of Chemistry

Published: 2016-12-16

Total Pages: 976

ISBN-13: 1849739633

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This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.


Synthesis of Heterocyclic Compounds

Synthesis of Heterocyclic Compounds

Author: A. L. Mndzhoian

Publisher: Springer Science & Business Media

Published: 2013-11-09

Total Pages: 155

ISBN-13: 1475766580

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The chemistry of heterocyclic compounds now forms one of the most extensive and important branches of organic chemistry. The rapid expansion of investigation in this field is due largely to the ever increasing practical importance of heterocyclic com pounds. The present stage in the development of organic chemistry and closely allied branches of biology is characterized by extensive investigation of physiologically active substances encountered in the plant and animal world and playing important parts in the life processes of micro- and macro-organisms. This extensive inves tigation of alkaloids, vitamins, hormones, antibiotics and their synthetic substitutes, and also of substances that control the bio chemical processes of the nervous system, has acted as a powerful stimulus to the further development of the chemistry of hetero cyclic compounds. Moreover, there are many well known applications of heterocyclic compounds in the manufacture of dyes, synthetic resins, synthetic rubbers, and other important materials. In response to growing demands, several monographs and treatises on the chemistry of heterocyclic compounds have appeared in recent years, the most comprehensive of these being the series "Heterocyclic Compounds," edited by R. C. Elderfield, which is already appearing in Russian translation. On the other hand, the lack of a practical guide to the laboratory preparation of hetero cyclic compounds is being felt more and more.


Multicomponent Reactions

Multicomponent Reactions

Author: K.L. Ameta, Ph.D.

Publisher: CRC Press

Published: 2017-09-20

Total Pages: 598

ISBN-13: 1315352737

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This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.