Vitamin D

Vitamin D

Author: Michael F. Holick

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 456

ISBN-13: 1475728611

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The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter refer virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authori ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences.


Delivering Superior Health and Wellness Management with IoT and Analytics

Delivering Superior Health and Wellness Management with IoT and Analytics

Author: Nilmini Wickramasinghe

Publisher: Springer Nature

Published: 2019-11-27

Total Pages: 686

ISBN-13: 303017347X

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This in-depth book addresses a key void in the literature surrounding the Internet of Things (IoT) and health. By systematically evaluating the benefits of mobile, wireless, and sensor-based IoT technologies when used in health and wellness contexts, the book sheds light on the next frontier for healthcare delivery. These technologies generate data with significant potential to enable superior care delivery, self-empowerment, and wellness management. Collecting valuable insights and recommendations in one accessible volume, chapter authors identify key areas in health and wellness where IoT can be used, highlighting the benefits, barriers, and facilitators of these technologies as well as suggesting areas for improvement in current policy and regulations. Four overarching themes provide a suitable setting to examine the critical insights presented in the 31 chapters: Mobile- and sensor-based solutions Opportunities to incorporate critical aspects of analytics to provide superior insights and thus support better decision-making Critical issues around aspects of IoT in healthcare contexts Applications of portals in healthcare contexts A comprehensive overview that introduces the critical issues regarding the role of IoT technologies for health, Delivering Superior Health and Wellness Management with IoT and Analytics paves the way for scholars, practitioners, students, and other stakeholders to understand how to substantially improve health and wellness management on a global scale.


Metabolomics: From Fundamentals to Clinical Applications

Metabolomics: From Fundamentals to Clinical Applications

Author: Alessandra Sussulini

Publisher: Springer

Published: 2017-01-28

Total Pages: 353

ISBN-13: 3319476564

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This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented. For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide detailed information about concepts and experimental aspects in metabolomics, as well as examples and perspectives of applications of this strategy to clinical questions.


Pocket Oncology

Pocket Oncology

Author: Alexander Drilon

Publisher: Lippincott Williams & Wilkins

Published: 2014

Total Pages: 352

ISBN-13: 1451187629

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Pocket Oncology, developed and edited by oncologists at Memorial Sloan-Kettering Cancer Center, is a simple, yet comprehensive, review of basic principles of cancer management. Prepared in the style and format of books in the popular Pocket Notebook series, Pocket Oncology is intended as a quick reference presented in easy to read bulleted text, and using diagrams and charts where appropriate. Each oncologic disease is presented on two facing pages that review initial clinical presentation, pathophysiology, staging, current standard of care treatments, and active areas of current research. Edited by Alexander Drilon and Michael Postow, the content of the book has been written by medical oncology fellows and each disease entity has been authoritatively reviewed by an oncologist with specific expertise in each subspecialty of oncology. Features: -simple, comprehensive, review of basic principles of oncology in easy to read bulleted text, using diagrams and charts where appropriate. -its small size makes it easy to carry the pocket of a lab coat for quick reference to information while in the hospital or oncology clinic. -perfect for medical students, residents, fellows, physician assistants, and nurses who perform daily oncologic care.


Ultraviolet Light in Human Health, Diseases and Environment

Ultraviolet Light in Human Health, Diseases and Environment

Author: Shamim I. Ahmad

Publisher: Springer

Published: 2017-11-08

Total Pages: 367

ISBN-13: 3319560174

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This book is about the roles and importance of Ultraviolet (UV) light from sun and from man-made UV lamps in our daily life, on health and diseases, also its application in sterilization and treatment. The key words are: reactive oxygen species, DNA damage, UV mutagenicity, skin cancers, polymorphous light eruption, Xeroderma pigmentosum, vitiligo, psoriasis, rheumatoid arthritis, diabetes mellitus, metabolic syndromes, cardiovascular diseases, dermatology, photobiology, photodermatosis, vitamin D synthesis, vitamin D efficiency, water sterilization, blood sterilization, phototherapies, skin tanning and UV dosimeter. The book starts with introduction to UV light and the history of development of UV lamps and its applications. It then moves to describing the interaction of this light with biological components and the production of reactive oxygen species, their roles in cell signaling, cellular defense from foreign invaders, in mutagenesis leading to skin diseases including vitiligo, polymorphous light eruption and various forms of skin cancer. Then it presents the synthesis and importance of UV light and diseases, induced due to the deficiency of vitamin D. Roles of UV light in sterilization, disinfection, phototherapies are depicted in the next part and finally use and abuse of UV light in tanning salon and the availability and importance of use of UV dosimeter are highlighted. The three main focuses of this book are: - Damage to biological systems by UV light leading to certain skin diseases; most importantly skin cancers. - Importance of UV light in the in vivo synthesis of vitamin D when human bodies are exposed to it. - Diseases caused due to the deficiency of vitamin D and the use of UV lamps in phototherapy and sterilization processes. The editor has considerable experience in publishing medical books and has used it critically selecting the matters which will attract the readers from many areas of medical and non-medical fields. It is hoped that the materials presented in this book will give great benefit and will stimulate both novice and expert researchers in the field. The book gives excellent overviews of the current status of research and pointers to the future research achievements. Clinicians, medical general practitioners, technicians and staff working in UV related industries and especially those working in tanning salon should benefit from the information presented in safe handling of this light.


Membrane Microdomain Signaling

Membrane Microdomain Signaling

Author: Mark P. Mattson

Publisher: Springer Science & Business Media

Published: 2005

Total Pages: 219

ISBN-13: 1588293548

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From intramolecular asymmetries to raft assemblies: a short guide for the puzzled in lipidomics / Ephraim Yavin and Annette Brand -- Regulatory aspects of membrane microdomain (raft) dynamics in live cells: a biophysical approach / János Matkó and János Szöllosi -- Lipid raft membrane skeletons / Elizabeth J. Luna ... [et al.] -- Role of cholesterol in membrane microdomain signaling / Christopher J. Fielding -- Raft lipid metabolism in relation to alkyl-lysophospholipid-induced apoptosis / Arnold H. van der Luit, Marcel Verheij, and Wim J. van Blitterswijk -- Role of lipid rafts in signal transduction and synaptic plasticity of neural cells / Markus Delling and Melitta Schachner -- Role of rafts in virus fusion and budding / Wu Ou and Jonathan Silver -- Alterations in raft lipid metabolism in aging and neurodegenerative disorders / Mark P. Mattson, Roy G. Cutler, and Norman J. Haughey -- Caveolin and cancer: a complex relationship / Mordechai Liscovitch ... [et al.] -- Dietary modulation of lipid rafts: implications for disease prevention and treatment / Mark P. Mattson.


A Picture is Worth a Thousand Tables

A Picture is Worth a Thousand Tables

Author: Andreas Krause

Publisher: Springer Science & Business Media

Published: 2012-12-12

Total Pages: 437

ISBN-13: 1461453291

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This book is devoted to the graphics of patient data: good graphs enabling straight¬forward and intuitive interpretation, efficient creation, and straightforward interpretation. We focus on easy access to graphics of patient data: the intention is to show a large variety of graphs for different phases of drug development, together with a description of what the graph shows, what type of data it uses, and what options there are. The main aim is to provide inspiration in form of a “graphics cookbook.” Many graphs provide creative ideas about what can be done. The book is not intended to be technical. It introduces general principles of good visualization to make readers understand the concepts, but the main focus is on the creativity and usefulness: readers are enabled to browse through the book to get ideas of how their own data can be analyzed graphically. For additional information visit Editor’s companion website: http://www.elmo.ch/doc/life-science-graphics/


Homosexual Behaviour in Animals

Homosexual Behaviour in Animals

Author: Volker Sommer

Publisher: Cambridge University Press

Published: 2006-07-27

Total Pages: 408

ISBN-13: 9780521864466

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Behavioural observations from both the field and captivity indicate that same-sex sexual interactions are widespread throughout the animal kingdom, and occur quite frequently in certain non-human species. Proximate studies of these phenomena have yielded important insights into genetic, hormonal and neural correlates. In contrast, there has been a relative paucity of research on the evolutionary aspects. Homosexual Behaviour in Animals seeks to readdress this imbalance by exploring animal same-sex sexual behaviour from an evolutionary perspective. Contributions focus on animals that routinely engage in homosexual behaviour and include birds, dolphin, deer, bison and cats, as well as monkey and apes, such as macaques, gorillas and bonobos. A final chapter looks at human primates. This book will appeal to graduate students and researchers in evolutionary biology, biological anthropology, zoology, evolutionary psychology, animal behaviour and anyone interested in the current state of knowledge in this area of behavioural studies.