Yukie Sakai is a sprightly young home health aide eager to help her elderly clients. But what seems like a straightforward job quickly turns into a series of increasingly surreal and bizarre adventures that put Yukie’s wits to the test! Cartoonist Kago, who is well known for combining a more traditional manga style with hyper realistic illustration technique, an experimental visual storytelling approach, and outrageously sexual and scatological subject matter, has single-handedly created his own genre: “fashionable paranoia."
Devilishly funny, absurdist manga short stories about a sprightly home aide caring for a series of eccentric patients. In Vol. 2, Yukie boldly decides to join the resistance ― against a squadron of maniacal diapers hell-bent on taking over the world! A shorthanded hospital hires zombies to care for its patients, but … what exactly do they eat? When an old man creates a machine that causes out-of-body experiences, what could possibly go wrong? And why are children getting rocket launchers in their stockings? Three words: Santa has dementia!
Fashionable-paranoia is a mix of splatter violence, humor and titillation, and manga artist, Shintaro Kago has helped define the genre over the last twenty years. Collecting fifteen different short stories from his illustrious care, this release compiles stories full of neurotic dark humor and unease.
Winner of the Michael Ramsay Prize 2016 Dementia is one of the most feared diseases in Western society today. Some have even gone so far as to suggest euthanasia as a solution to the perceived indignity of memory loss and the disorientation that accompanies it. Here, John Swinton develops a practical theology of dementia for caregivers, people with dementia, ministers, hospital chaplains, and medical practitioners as he explores two primary questions: • Who am I when I’ve forgotten who I am? • What does it mean to love God and be loved by God when I have forgotten who God is? Offering compassionate and carefully considered theological and pastoral responses to dementia and forgetfulness, Swinton’s Dementia redefines dementia in light of the transformative counter story that is the gospel.
A biography by Nicole Rudick told in Saint Phalle's own words, assembled from rare and unseen materials Known best for her exuberant, often large-scale sculptural works that celebrate the abundance and complexity of female desire, imagination and creativity, Niki de Saint Phalle viewed making art as a ritual, a performance--a process connecting life to art. This unconventional, illuminated biography, told in the first person in Saint Phalle's voice and her own hand, dilates large and small moments in Saint Phalle's life which she sometimes reveals with great candor, at other times carefully unwinding her secrets. Editor Nicole Rudick, in a kind of collaboration with the artist, has assembled a gorgeous and detailed mosaic of Saint Phalle's visual and textual works from a trove of paintings, drawings, sketches and writings, many previously unpublished or long unavailable, that trace her mistakes and successes, her passions and her radical sense of joy. Saint Phalle's invocation--her "bringing to life"--writes Rudick, "is an apt summation of the overlap of Saint Phalle's life and art: both a bringing into existence and a bringing to bear. These are visions from the frontiers of consciousness." Born in France, Niki de Saint Phalle (1930-2002) was raised in New York and began making art at age 23, pursuing a revelatory vision informed both by the monumental works of Antonin Gaudí and the Facteur Cheval, and by aspects of her own life. In addition to her Tirs ("shooting paintings") and Nanas and her celebrated large-scale projects--including the Stravinsky Fountain at the Centre Pompidou, Golem in Jerusalem and the Tarot Garden in Tuscany--Saint Phalle produced writing and works on paper that delve into her own biography: childhood and her break with her family, marriage to Harry Mathews, motherhood, a long collaborative relationship with Jean Tinguely, numerous health crises and her late, productive years in Southern California. Saint Phalle has most recently been the subject of retrospectives at the Guggenheim Museum Bilbao, in 2015, and at MoMA P.S.1, in 2021. Nicole Rudick is a critic and an editor. Her writing on art, literature and comics has been published in the New York Review of Books, the New York Times, the New Yorker, Artforum and elsewhere. She was managing editor of the Paris Review for nearly a decade. She is the editor, most recently, of a new edition of Gary Panter's legendary comic Jimbo: Adventures in Paradise (New York Review Comics, 2021).
This gripping story of the doctors at the forefront of Alzheimer’s research and the courageous North Dakota family whose rare genetic code is helping to understand our most feared diseases is “excellent, accessible...A science text that reads like a mystery and treats its subjects with humanity and sympathy” (Library Journal, starred review). Every sixty-nine seconds, someone is diagnosed with Alzheimer’s disease. Of the top ten killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer’s, an inherited genetic mutation that causes the disease in one hundred percent of cases, and has a fifty percent chance of being passed onto the next generation. Of the six DeMoe children whose father had it, five have inherited the gene; the sixth, daughter Karla, has inherited responsibility for all of them. But rather than give up in the face of such news, the DeMoes have agreed to spend their precious, abbreviated years as part of a worldwide study that could utterly change the landscape of Alzheimer’s research and offers the brightest hope for future treatments—and possibly a cure. Drawing from several years of in-depth research with this charming and upbeat family, journalist Niki Kapsambelis tells the story of Alzheimer’s through the humanizing lens of these ordinary people made extraordinary by both their terrible circumstances and their bravery. “A compelling narrative…and an educational and emotional chronicle” (Kirkus Reviews, starred review), their tale is intertwined with the dramatic narrative history of the disease, the cutting-edge research that brings us ever closer to a possible cure, and the accounts of the extraordinary doctors spearheading these groundbreaking studies. From the oil fields of North Dakota to the jungles of Colombia, this inspiring race against time redefines courage in the face of this most pervasive and mysterious disease.
Under the name of Frontotemporal Dementias (FTD) numerous hereditary and sporadic disorders are listed. FTD may take away speech and language, social skills and ethical judgement, wishes and will, empathy and emotions; it may also impair motor functions. FTD may affect men and women in midlife or during old age leading to the demolition of the uniqueness of the human mind. In the last decade of the 20th century and in the first two decades of the 21st century, progress in the understanding of clinical, neuropathological, biochemical, and genetic aspects of FTD has accelerated. The novel awareness about FTD has directed young generations of researchers toward the study of this complex group of disorders. This Volume has been formulated with the participation of some of the leading scientists who have contributed to the development of knowledge in the clinical and basic science arenas. It captures the current central elements that are relevant to an up-to-date understanding of causes and pathogenesis of multiple forms of FTD. The volume is an opus that represents a distillation of the work of many scientists and addresses the current directions in the study of one of the most complex groups of diseases. In view of its structure, the book could also be used as a textbook, that offers both a broad and deep analysis of major areas in FTD. This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress. The authors of each chapter share their knowledge and vision aimed at reducing the suffering which is caused by FTD.
Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.