Biological Resource Centers

Biological Resource Centers

Author: Scott Stern

Publisher: Rowman & Littlefield

Published: 2004-11-30

Total Pages: 141

ISBN-13: 0815797540

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Biological resource centers (BRCs) collect, certify, and distribute organisms for use in research and in the development of commercial products in the pharmaceutical, agricultural, and biotechnology industries. They maintain a large and varied collection, including cell lines, micro-organisms, recombinant DNA material, biological media and reagents, and the information technology tools that allow researchers to access biological materials. BRCs have established themselves as a crucial element in the life science innovation infrastructure, from their early impact on virology, to their crucial role in addressing cross-culture contamination in the 1970s, to their current leadership in promoting a global biodiversity network. Today they confront new challenges, resulting from shifts in the nature of biological research, the interaction between public and private researchers, and the increasing focus on biosecurity. This book provides a systematic economic assessment of the impact of biological resource centers through their role in facilitating cumulative knowledge in the life sciences and building on their roles as knowledge hubs—institutions that facilitate the transfer of scientific and technical knowledge among members of a research community. The knowledge hubs framework offers insight into how to develop and evaluate policy proposals that impinge on the control and access of biological materials. Stern argues that science and innovation policy must be premised on a clear understanding of the role that knowledge hubs play and the policy mechanisms that encourage their sustained growth and effectiveness.


OECD Best Practice Guidelines for Biological Resource Centres

OECD Best Practice Guidelines for Biological Resource Centres

Author: OECD

Publisher: OECD Publishing

Published: 2007-03-28

Total Pages: 115

ISBN-13: 926412876X

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These best practice guidelines are intended to serve as a target for the quality management of biological resource center collections. They are the result of discussions held by OECD member countries together with a number of key partner countries ...


The Biological Resources of Model Organisms

The Biological Resources of Model Organisms

Author: Robert L. Jarret

Publisher: CRC Press

Published: 2019-07-16

Total Pages: 282

ISBN-13: 1351587773

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This book discusses 14 model organisms and are used by thousands of researchers, teachers, and students each year in laboratories and classrooms, around the globe. Though acknowledged in innumerable scientific journal articles, little is generally known about the origin of these collections, how the organisms contained within them have been acquired, and how they are maintained and distributed. While some collections such as Drosophila have long histories others, such as the collection of Brachionus, are relatively new. They vary greatly in size. Yet, all have contributed and are continuing to contribute to global research efforts in many areas of scientific research as diverse as tissue regeneration, skin cancer, evolution, water purity, gene function, and hundreds of others. In addition to providing the raw materials for national and international research programs, these collections also provide educational tools used by colleges and high schools. The chapters in this book attempt to provide a brief look at the individual organisms, how they came to be accepted as model organisms, the history of the individual collections, examples of how the organisms have been and are being used in scientific research, and a description of the facilities and procedures used to maintain them. Features: • Provides an in-depth look at the collections of 14 model organisms that have enabled innumerable scientific breakthroughs over decades, and that continue to do so. • Includes detailed descriptions of the operating procedures used for the maintenance of each model organism collection. • Discusses the holdings of the collections of model organisms and its relevance to past, current and future scientific research. • Written by the leaders in the field of the management of model organisms.