Antioxidant-Antidiabetic Agents and Human Health
Antioxidant-Antidiabetic Agents and Human Health

Author: Oluwafemi Oguntibeju

Publisher: BoD – Books on Demand

Published: 2014-02-05

Total Pages: 384

ISBN-13: 9535112155

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The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.

Antioxidants in Diabetes Management
Antioxidants in Diabetes Management

Author: Peter Rosen

Publisher: CRC Press

Published: 2000-02-18

Total Pages: 380

ISBN-13: 9780824788445

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This volume summarizes current understanding of the pathogenic role of oxidative stress in the onset and progression of diabetes and its complications, and presents results of studies aimed at regulating oxidatively induced complications through the use of antioxidants. Examines the presence of impaired microcirculation, capillary hypoxia, and ischemia syndrome in diabetic complications! Designed to stimulate scientific discussion and curiosity about the causes of diabetes, with contributions from nearly 65 clinicians and researchers who cite more than 1300 sources, Antioxidants in Diabetes Management focuses on stringent control of hyperglycemia to prevent or modify onset and progression promotes the development of intervention strategies because of the therapeutic limitations of hypoglycemic therapy emphasizes the potential synergistic effects of an interlinked antioxidant network investigates the controversy surrounding the significance of oxidative stress markers in diabetes highlights oxidative stress and antioxidant treatment in animal models for juvenile and adult onset diabetes explores the hypothesis that ischemic reperfusion is the primary cause of diabetic polyneuropathy links protein kinase C activation to the development of diabetic vascular complications and the effectiveness of vitamin E in preventing these abnormalities spotlights recent clinical trials of therapeutic effects of antioxidants to reduce insulin resistance and much more! Illustrating the therapeutic potential of antioxidants for the treatment of diabetes, Antioxidants in Diabetes Management is an unparalleled reference for endocrinologists, nutritionists and dietitians, cell biologists and biochemists, cardiologists, pathologists, and graduate and medical school students in these disciplines.

Bioactive Food as Dietary Interventions for Cardiovascular Disease
Bioactive Food as Dietary Interventions for Cardiovascular Disease

Author: Ronald Ross Watson

Publisher: Academic Press

Published: 2012-10-23

Total Pages: 722

ISBN-13: 0123964857

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One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that oxidative stress is implicated in the physiology of several major cardiovascular diseases including heart failure and increased free radical formation and reduced antioxidant defences. Studies indicate bioactive foods reduce the incidence of these conditions, suggestive of a potential cardioprotective role of antioxidant nutrients. Bioactive Food as Dietary Interventions for Cardiovascular Disease investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease. It reviews existing literature, and presents new hypotheses and conclusions on the effects of different bioactive components of the diet. Addresses the most positive results from dietary interventions using bioactive foods to impact cardiovascular disease Documents foods that can affect metabolic syndrome and other related conditions Convenient, efficient and effective source that allows readers to identify potential uses of compounds - or indicate those compounds whose use may be of little or no health benefit Associated information can be used to understand other diseases that share common etiological pathways

Diabetes
Diabetes

Author: Victor R Preedy

Publisher: Academic Press

Published: 2020-04-24

Total Pages: 456

ISBN-13: 0128157771

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Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer. - Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of diabetes and oxidation issues - Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet, its food matrix or plant - Includes preclinical, clinical and population studies to help endocrinologists, diabetologists, nutritionists, dieticians and clinicians map out key areas for research and further clinical recommendations

Oxidative Stress and Chronic Degenerative Diseases
Oxidative Stress and Chronic Degenerative Diseases

Author: Jose Antonio Morales-Gonzalez

Publisher: BoD – Books on Demand

Published: 2013-05-22

Total Pages: 516

ISBN-13: 953511123X

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This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.

Fight Diabetes with Vitamins and Antioxidants
Fight Diabetes with Vitamins and Antioxidants

Author: Kedar N. Prasad

Publisher: Healing Arts Press

Published: 2014-03-07

Total Pages: 0

ISBN-13: 9781620551660

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The most up-to-date and complete resource on the powerful benefits of micronutrients for diabetes treatment and prevention • Provides an easy-to-follow program of nutritional supplements to halt progression of diabetes and its complications and to improve your odds of avoiding diabetes • Shows how merely changing your diet and activity level cannot fully counteract the chronic inflammation and free radical damage at the source of diabetes and prediabetes • Debunks the flawed conclusions of the medical community that show vitamins and antioxidants to be ineffective for diabetes treatment In this practical yet scientific guide, leading researcher in cancer, heart disease, and diabetes prevention Kedar N. Prasad, Ph.D., reveals the latest revolutionary discoveries on the use of antioxidants and micronutrients to treat diabetes. He details how the proper combinations of vitamin and antioxidant supplements can greatly increase the effectiveness of standard medical treatments to halt and even reverse the progression of both type I and type II diabetes and prevent onset in those who are diagnosed as prediabetic. Prasad shows how chronic inflammation, oxidative stress, and free radical damage are the chief culprits for the progression of diabetes and its complications and that merely changing your diet and activity level and regulating blood glucose levels cannot fully counteract this unhealthy internal state. He provides an easy-to-follow daily supplement regime for both diabetics and prediabetics in multiple age groups to target free radical damage and cell injury and stop the progression of diabetes complications. Reviewing much of the scientific research on diabetes treatment, he debunks the flawed conclusions of the medical community that vitamins and antioxidants are ineffective, revealing how the studies focused on specific micronutrients rather than synergistic combinations. Offering the missing complement to the standard care of diet, exercise, and lifestyle changes promoted by mainstream medicine, this guide provides a truly holistic approach to diabetes prevention, treatment, and care.

Atlas of Diabetes
Atlas of Diabetes

Author: Jay Skyler

Publisher: Springer Science & Business Media

Published: 2012-03-08

Total Pages: 424

ISBN-13: 1461410282

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This handbook is an invaluable resource for improving the management of diabetes. Chapters cover the fundamentals, including epidemiology, history and physical examination, and functional evaluations. Diabetes in children, adolescents, adults, and geriatrics are addressed. Differential diagnosis is emphasized, and evidence-based guidelines and patient-specific considerations aid the reader with injury evaluation and care. Notably, the book highlights the importance of understanding diabetic symptoms when determining the source of illnesses. In addition, the text presents the spectrum of treatment options for diabetes. The book is complete with appendices that explain the evidence-based approach used throughout and the science behind therapeutic modalities.

Diabetes Mellitus
Diabetes Mellitus

Author: Derek LeRoith

Publisher: Lippincott Williams & Wilkins

Published: 2004

Total Pages: 1608

ISBN-13: 9780781740975

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Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.

Dr. Neal Barnard's Program for Reversing Diabetes
Dr. Neal Barnard's Program for Reversing Diabetes

Author: Neal Barnard

Publisher: Rodale Books

Published: 2018-02-27

Total Pages: 362

ISBN-13: 163565128X

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Tackle diabetes and its complications for good with this newly updated edition of Dr. Neal Barnard's groundbreaking program. Revised and updated, this latest edition of Dr. Barnard’s groundbreaking book features a new preface, updates to diagnostic and monitoring standards, recent research studies, and fresh success stories of people who have eliminated their diabetes by following this life-changing plan. Before Dr. Barnard’s scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it—and could anticipate one health issue after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But this simply is not true—Dr. Barnard has shown that it is often possible to improve insulin sensitivity and tackle type 2 diabetes by following his step-by-step plan, which includes a healthful vegan diet with plenty of recipes to get started, an exercise guide, advice about taking supplements and tracking progress, and troubleshooting tips.

Systems Biology of Free Radicals and Antioxidants
Systems Biology of Free Radicals and Antioxidants

Author: Ismail Laher

Publisher: Springer

Published: 2014-06-16

Total Pages: 0

ISBN-13: 9783642300172

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The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.