Introduction to Mathematical Oncology
Introduction to Mathematical Oncology

Author: Yang Kuang

Publisher: CRC Press

Published: 2016-04-05

Total Pages: 469

ISBN-13: 1584889918

DOWNLOAD EBOOK

Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.

Introduction to Cancer Biology
Introduction to Cancer Biology

Author: Robin Hesketh

Publisher: Cambridge University Press

Published: 2013

Total Pages: 355

ISBN-13: 1107013984

DOWNLOAD EBOOK

A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.

An Introduction to Physical Oncology
An Introduction to Physical Oncology

Author: Vittorio Cristini

Publisher: CRC Press

Published: 2017-06-26

Total Pages: 204

ISBN-13: 1466551364

DOWNLOAD EBOOK

Physical oncology has the potential to revolutionize cancer research and treatment. The fundamental rationale behind this approach is that physical processes, such as transport mechanisms for drug molecules within tissue and forces exchanged by cancer cells with tissue, may play an equally important role as biological processes in influencing progression and treatment outcome. This book introduces the emerging field of physical oncology to a general audience, with a focus on recent breakthroughs that help in the design and discovery of more effective cancer treatments. It describes how novel mathematical models of physical transport processes incorporate patient tissue and imaging data routinely produced in the clinic to predict the efficacy of many cancer treatment approaches, including chemotherapy and radiation therapy. By helping to identify which therapies would be most beneficial for an individual patient, and quantifying their effects prior to actual implementation in the clinic, physical oncology allows doctors to design treatment regimens customized to each patient’s clinical needs, significantly altering the current clinical approach to cancer treatment and improving the outcomes for patients.

Basics of Oncology
Basics of Oncology

Author: Frederick O Stephens

Publisher: Springer Science & Business Media

Published: 2009-04-29

Total Pages: 377

ISBN-13: 3540929258

DOWNLOAD EBOOK

"Basics of Oncology" provides an easily understood and general overview of the basic medical, scientific and clinical aspects of cancer. Causes, pathology, clinical features, diagnostic investigations, treatments and outcomes are all carefully explained and discussed, both for cancers in general and for the common cancers in individual countries. The reader will thereby be provided with an understanding of how and why people develop cancer, how the body reacts to cancer, what can be done to prevent the disease, and how the various cancers are best diagnosed and treated. The book will serve as a sound basis for the more detailed or specific studies that may be needed in different areas of practice and in different countries. It will be invaluable for students of medicine, nurse oncologists, students of medical sciences and other health professionals in all parts of the world.

Fundamentals of Radiation Oncology
Fundamentals of Radiation Oncology

Author: Hasan Murshed

Publisher: Academic Press

Published: 2019-01-05

Total Pages: 744

ISBN-13: 0128141298

DOWNLOAD EBOOK

Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Third Edition continues to provide current, concise, and a readily available source of clinical information for busy practicing radiation oncologists. The book consists of 26 chapters, divided into four parts: Part I describes the basic science of radiation oncology, with discussions of radiation physics, radiation protection, and radiation biology, as well as molecular biology. Part II describes techniques and modalities of radiation oncology including brachytherapy, intensity-modulated radiation therapy (IMRT), stereotactic radiotherapy (SRS), stereotactic body radiation therapy (SBRT), and proton therapy. Significant recent advances made in the areas of immunotherapy and combined modality therapy; as such, these chapters have also been added to this new edition. Part III describes the clinical science of radiation oncology including risk factors, symptoms/signs, and investigations needed for the cancer diagnosis and up-to-date treatment recommendations in accordance with the new AJCC staging system. In addition, radiation treatment techniques, with an emphasis on IMRT, have been expanded to all the chapters. Also included in this version of the book is a chapter on benign diseases. Updated annotated bibliographies of latest landmark studies providing evidence-based rationale for the recommended treatments are presented at the end of each chapter. Part IV describes palliative radiation treatments to improve the quality of life for cancer patients and the management of side effects from radiation treatment. This book is a must-have for all radiation oncology residents, radiation oncologists and all professionals engaged in the care of cancer patients. - New chapters on brachytherapy, IMRT/IGRT, SRS, SBRT, proton therapy, immunotherapy, combined modality therapy, and benign diseases - Eighth edition of the AJCC staging system - IMRT techniques for all common cancer sites, along with up-to-date treatment recommendations - Relevant, landmark studies that provide evidence-based rationale for recommended treatments

Dynamics of Cancer
Dynamics of Cancer

Author: Steven A. Frank

Publisher: Princeton University Press

Published: 2018-06-05

Total Pages: 393

ISBN-13: 0691186863

DOWNLOAD EBOOK

The onset of cancer presents one of the most fundamental problems in modern biology. In Dynamics of Cancer, Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset. The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer. This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.

Physics of Cancer
Physics of Cancer

Author: Claudia Mierke

Publisher: Iph001

Published: 2018-10-24

Total Pages: 500

ISBN-13: 9780750317511

DOWNLOAD EBOOK

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

Ecology and Evolution of Cancer
Ecology and Evolution of Cancer

Author: Beata Ujvari

Publisher: Academic Press

Published: 2017-02-08

Total Pages: 292

ISBN-13: 0128043806

DOWNLOAD EBOOK

Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. - Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine - Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors - Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems - Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies

The Cancer Book
The Cancer Book

Author: Geoffrey M. Cooper

Publisher: Jones & Bartlett Learning

Published: 1993

Total Pages: 252

ISBN-13: 9780867207705

DOWNLOAD EBOOK

Written in non-technical language, this book helps the reader understand the basic nature and causes of cancer, as well as the principles underlying current strategies for cancer prevention and treatment. By presenting an overview and perspective of both the basic and practical aspects of cancer, including the background needed to understand continuing advances in the field. The book is fascinating reading and an ideal book for everyone interested in the subject.