Adverse Effects of Pertussis and Rubella Vaccines
Adverse Effects of Pertussis and Rubella Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1991-02-01

Total Pages: 382

ISBN-13: 0309103681

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Parents have come to depend on vaccines to protect their children from a variety of diseases. Some evidence suggests, however, that vaccination against pertussis (whooping cough) and rubella (German measles) is, in a small number of cases, associated with increased risk of serious illness. This book examines the controversy over the evidence and offers a comprehensively documented assessment of the risk of illness following immunization with vaccines against pertussis and rubella. Based on extensive review of the evidence from epidemiologic studies, case histories, studies in animals, and other sources of information, the book examines: The relation of pertussis vaccines to a number of serious adverse events, including encephalopathy and other central nervous system disorders, sudden infant death syndrome, autism, Guillain-Barre syndrome, learning disabilities, and Reye syndrome. The relation of rubella vaccines to arthritis, various neuropathies, and thrombocytopenic purpura. The volume, which includes a description of the committee's methods for evaluating evidence and directions for future research, will be important reading for public health officials, pediatricians, researchers, and concerned parents.

Adverse Effects of Vaccines
Adverse Effects of Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-04-26

Total Pages: 894

ISBN-13: 0309214351

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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Adverse Events Associated with Childhood Vaccines
Adverse Events Associated with Childhood Vaccines

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1993-01-01

Total Pages: 481

ISBN-13: 0309048958

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Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.

Immunization Safety Review
Immunization Safety Review

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2003-11-26

Total Pages: 118

ISBN-13: 0309168910

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The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

Canadian Immunization Guide
Canadian Immunization Guide

Author: Canada. Comité consultatif national de l'immunisation

Publisher:

Published: 2006

Total Pages: 392

ISBN-13: 9780660193922

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The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

The Childhood Immunization Schedule and Safety
The Childhood Immunization Schedule and Safety

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2013-04-27

Total Pages: 237

ISBN-13: 0309267021

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Vaccines are among the most safe and effective public health interventions to prevent serious disease and death. Because of the success of vaccines, most Americans today have no firsthand experience with such devastating illnesses as polio or diphtheria. Health care providers who vaccinate young children follow a schedule prepared by the U.S. Advisory Committee on Immunization Practices. Under the current schedule, children younger than six may receive as many as 24 immunizations by their second birthday. New vaccines undergo rigorous testing prior to receiving FDA approval; however, like all medicines and medical interventions, vaccines carry some risk. Driven largely by concerns about potential side effects, there has been a shift in some parents' attitudes toward the child immunization schedule. The Childhood Immunization Schedule and Safety identifies research approaches, methodologies, and study designs that could address questions about the safety of the current schedule. This report is the most comprehensive examination of the immunization schedule to date. The IOM authoring committee uncovered no evidence of major safety concerns associated with adherence to the childhood immunization schedule. Should signals arise that there may be need for investigation, however, the report offers a framework for conducting safety research using existing or new data collection systems.

The Causes of Epilepsy
The Causes of Epilepsy

Author: Simon Shorvon

Publisher: Cambridge University Press

Published: 2019-05-02

Total Pages: 1013

ISBN-13: 1108420753

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Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book
Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition E-Book

Author: Jennifer Hamborsky, MPH, MCHES

Publisher: Public Health Foundation

Published: 2015-10-19

Total Pages: 738

ISBN-13: 0990449122

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The Public Health Foundation (PHF) in partnership with the Centers for Disease Control and Prevention (CDC) is pleased to announce the availability of Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition or “The Pink Book” E-Book. This resource provides the most current, comprehensive, and credible information on vaccine-preventable diseases, and contains updated content on immunization and vaccine information for public health practitioners, healthcare providers, health educators, pharmacists, nurses, and others involved in administering vaccines. “The Pink Book E-Book” allows you, your staff, and others to have quick access to features such as keyword search and chapter links. Online schedules and sources can also be accessed directly through e-readers with internet access. Current, credible, and comprehensive, “The Pink Book E-Book” contains information on each vaccine-preventable disease and delivers immunization providers with the latest information on: Principles of vaccination General recommendations on immunization Vaccine safety Child/adult immunization schedules International vaccines/Foreign language terms Vaccination data and statistics The E-Book format contains all of the information and updates that are in the print version, including: · New vaccine administration chapter · New recommendations regarding selection of storage units and temperature monitoring tools · New recommendations for vaccine transport · Updated information on available influenza vaccine products · Use of Tdap in pregnancy · Use of Tdap in persons 65 years of age or older · Use of PCV13 and PPSV23 in adults with immunocompromising conditions · New licensure information for varicella-zoster immune globulin Contact [email protected] for more information. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page

A Shot in the Dark
A Shot in the Dark

Author: Harris Livermore Coulter

Publisher: Penguin

Published: 1991-01-01

Total Pages: 268

ISBN-13: 9780895294630

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Every week, tens of thousands of children across America are injected with the DPT (diphtheria-pertussis-tetanus) vaccine. The law requires it, and most children will get four DPT shots before they are two years old. But what if one of the components of the vaccine was not safe? What if it caused not only pain, swelling, screaming, and high fever, but also shock, convulsions, brain damage, and even death? And, to make matters worse, what if there were a safer alternative but parents didn't know about it? Wouldn't the government require the drug manufacturers to produce the safer vaccine to protect the lives of the children who might otherwise suffer the shot's crippling side effects? The answer is, unfortunately, no. A Shot in the Dark is a chilling account of just how dangerous the whole-cell pertussis vaccine (the "P" part of the DPT shot) has proven to be. It provides accurate research into the history of the vaccine's development and usage. It exposes the roles played by the FDA and drug companies. It tells the tragic stories of the young victims of the vaccine. This book is also a guide for rightfully concerned parents who are looking for answers to important questions. What are the warning signs to look for to tell if your child is likely to be sensitive to the vaccine? What should parents ask their doctors about the vaccine and their child's medical profile? What is being done, here and in other countries, to combat this frightening situation? What can parents do now to help? A Shot in the Dark is a responsible, eye-opening look at a potential problem that every parent of every young child living in this country must face. Armed with the facts in this important book, parents will be able to make informed decisions about their real medical options. Book jacket.

Vaccines
Vaccines

Author: Paul A. Offit

Publisher: John Wiley & Sons

Published: 2003-05-13

Total Pages: 257

ISBN-13: 0471470325

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Get the straight facts about vaccines and make informed choices Do you wonder whether vaccines are safe and whether they are all really necessary? This completely revised and updated edition of the classic Vaccines: What You Should Know helps you sort through the latest information about vaccines in order to determine what is right for your family. Coauthored by Paul Offit, a member of the CDC advisory committee that determines which vaccines are recommended for use in the United States, this guide tells you what vaccines are made of and clearly explains how they are made, how they work, and the risks associated with them. This updated edition includes recommendations for the smallpox vaccine, the latest information on vaccines for travelers, and the latest on the progress of combination vaccines. Expanded information on vaccine safety includes discussion of vaccines and autism, mercury in vaccines, and the ability of children to tolerate numerous vaccines at once.