Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology
Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology

Author: Luiz Belardinelli

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 515

ISBN-13: 1461520118

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This book contains a selection of lectures given during the 5th International Symposium on Adenosine and Adenine Nucleotides, recently held in Philadelphia, Pennsylvania. Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology covers a wide range of subjects from molecular and cellular biology to clinical applications. A great emphasis has been placed on cutting edge information derived from studies using molecular and cellular biology techniques applied to the field of adenosine and adenine nucleotide research. The book also includes information on potentially promising developments in the therapeutic applications of adenosine related drugs and ATP. The tradition of past meetings is also maintained by including in the program presentations of new research in the areas of purine metabolism and physiology, and pharmacology of adenosine and adenine nucleotides. Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology is an excellent, up-to-date reference book for basic and clinical scientists in the field of adenosine and adenine nucleotides.

Adenosine and Adenine Nucleotides As Regulators of Cellular Function
Adenosine and Adenine Nucleotides As Regulators of Cellular Function

Author: John W. Phillis

Publisher: CRC Press

Published: 1991-06-14

Total Pages: 460

ISBN-13: 9780849369285

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This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various aspects of the formation, metabolism, release, transport, and receptors for endogenous adenosine and the adenosine triphosphate; functions of purines at the cellular level; the role of adenosine in the regulation of flow in different vascular beds; and angiogenesis. The book also addresses the purinergic regulation of the cardiac, renal, gastro-intestinal, and central nervous system, as well as potential therapeutic avenues for purine use. The book will be valuable to physiologists, pharmacologists, and other basic and clinical scientists interested in updating their knowledge of the expanding biological roles of these substances.

Role of Adenosine and Adenine Nucleotides in the Biological System
Role of Adenosine and Adenine Nucleotides in the Biological System

Author: Shōichi Imai

Publisher: Elsevier Publishing Company

Published: 1991

Total Pages: 748

ISBN-13:

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This book provides a broad view of the current research activities in adenosine and adenine nucleotide research, with contributions from many leading experts in the field. Like the three previous Symposia, the 4th International Symposium on Adenosine was designed to integrate the recent advances made in the rapidly expanding field of adenosine research by various biological and medical disciplines. Over 70 presentations were made, with over 60 posters displayed, and all the papers presented by the invited speakers and related discussions, as originally submitted by the authors are contained in this proceedings. This comprehensive text covers all important aspects of the subject and is a must for any scientist with an interest in adenosine research.

Methods Used in Adenosine Research
Methods Used in Adenosine Research

Author: David Paton

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 385

ISBN-13: 1468448862

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In their classic paper in 1929, Drury and Szent-Gyorgyi described a number of the important cardiovascular actions of adenosine. Another thirty years were to pass before the possible physiological role of adenosine in coronary vasodilation was studied by Berne and others. Since then, there has been a tremendous increase in research into the actions of adenosine. Workers from many disciplines have employed a wide variety of techniques, since adenosine is a product of and a substrate for a number of metabolic pathways, is transported into cells, and acts at discrete receptor sites to modulate the activity of adenylate cyclase and to produce important actions on many cells and tissues including platelets, adipo cytes, heart, blood vessels, and other smooth muscles. International symposia on the actions of adenosine were held in 1978, 1981, and 1982, and the proceedings of these symposia have been published (Baer and Drummond, 1979; Daly et at., 1983; Berne et at., 1983). Since it is not the primary purpose of the present volume to review our current understanding of the nu merous actions of adenosine, these volumes should be consulted for such details. Rather, the present volume has been planned to provide both graduate students and investigators in pharmacology and related disciplines with a summary of some of the methods now available for the study of the actions of adenosine and, in particular, to highlight their possible uses and limitations.

Purine Metabolism in Man-III
Purine Metabolism in Man-III

Author: A. Rapado

Publisher: Springer

Published: 1980-09

Total Pages: 480

ISBN-13:

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However, there have been many new developments during the last three years and the scope of the communications reflects not only increasing depth of knowledge, but also a widening of the field. This publication has clinical and fundamental implications for internal medicine, pediatrics, urology, biochemistry, immunology, genetics, and oncology. It is interesting to compare the scope of this volume with that of its predecessors. The main emphasis has shifted from the study of gout and the dissection of metabolic pathways to encompass investigations in the fields of oncology, immunology, and lymphocyte physiology. There are pointers to possible implications in relation to cardiology and neuromuscular diseases, which may well prove to be growing points for the future. In spite of considerable work on the mechanism of urinary stone formation, the inter-relationship between uric acid and calcium oxalate urolithiasis remains obscure.