Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery

Author: Ryan F. Donnelly

Publisher: John Wiley & Sons

Published: 2015-09-28

Total Pages: 290

ISBN-13: 1118734513

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This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.

Introduction of Novel Drug Delivery Systems
Introduction of Novel Drug Delivery Systems

Author: Sonal Vyas

Publisher: CBS Publishers & Distributors Pvt Limited, India

Published: 2020-01-30

Total Pages:

ISBN-13: 9789388527811

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This is a useful textbook and resource for undergraduateand postgraduate students and anyone in the working concepts of a drug delivery system and its performance. A novel drug delivery system refers to strategy, technology, formulation-based approaches and customized system(s) developed for safe administration and within body transportation of drugs as needed for optimum therapeutic benefits while ensuring minimum to nil toxic effects. Multidisciplinary approaches and cutting edge technology have been used to develop the carrier modules to deliver the contained drug to the target tissues in a preprogrammed manner. The process desirably modifies the drug distribution and accumulation, thereby producing optimum therapeutic effects. Carrier-mediated drug delivery has emerged as a powerful technology for the treatment of various difficult pathologies. The therapeutic index of conventional and novel drug is enhanced owing to specificity due to targeting of drug to the particular tissue. This book includes an introduction to novel drug delivery, oral osmotic pumps, bioadhesive and mucoadhesive systems, multiple emulsions, colon-specific drug delivery systems, transdermal drug delivery systems, spherical crystallization, microemulsion, implants and inserts, micellar systems, liposomes, microspheres and microcapsules, nanoparticles, resealed erythrocytes, transfersomes and ethosomes, organogels, dendrimers, niosomes, solid lipid nanoparticles, drug conjugates, cyclodextrin complexes, multifunctional nanomedicines, and floating drug delivery system(s). Each chapter attempts to discuss introduction, concept, progress, status and future prospects of the concerned novel drug delivery system.

Novel Drug Delivery Systems
Novel Drug Delivery Systems

Author: Yie Chien

Publisher: CRC Press

Published: 2019-08-30

Total Pages: 816

ISBN-13: 9780367402914

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A comprehensive treatment of the science, technology, and regulation of rate-controlled administration of therapeutic agents, with coverage of the basic concepts, fundamental principles, biomedical rationales, and potential applications. This revised and updated edition (first in 1982) incorporates

Novel Drug Delivery Technologies
Novel Drug Delivery Technologies

Author: Ambikanandan Misra

Publisher: Springer Nature

Published: 2020-02-12

Total Pages: 448

ISBN-13: 9811336423

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The application of drug delivery is a valuable, cost-effective lifecycle management resource. By endowing drugs with new and innovative therapeutic benefits, drug delivery systems extend products’ profitable lifecycle, giving pharmaceutical companies competitive and financial advantages, and providing patients with improved medications. Formulation development is now being used to create new dosage forms for existing products, which not only reduces the time and expense involved in new drug development, but also helps with regard to patent protection and bypassing existing patents. Today’s culture demands convenience, a major factor determining adherence to drug therapy. Over the past few years, patient convenience-oriented research in the field of drug delivery has yielded a range of innovative drug-delivery options. As a result, various drug-delivery systems, including medicated chewing gums, oral dispersible tablets, medicated lozenges and lollipops, have now hit the market and are very popular. These dosage forms offer a highly convenient way to dose medications, not only for special population groups with swallowing difficulties, such as children and the elderly, but for the general populace as well. This book provides valuable insights into a number of formulation design approaches that are currently being used, or could be used, to provide new benefits from existing drug molecules.

Drug Delivery Systems, Third Edition
Drug Delivery Systems, Third Edition

Author: Vasant V. Ranade

Publisher: CRC Press

Published: 2011-04-25

Total Pages: 610

ISBN-13: 1439806187

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Drug delivery technologies represent a vast, vital area of research and development in pharmaceuticals. The demand for innovative drug delivery systems continues to grow, driving a variety of new developments. Drug Delivery Systems, Third Edition provides a comprehensive review of the latest research and development on drug delivery systems. Coverage includes liposomal, transmucosal, transdermal, oral, polymeric, and monoclonal antibody directed delivery. Each chapter provides a table of marketed and investigational products with numerous practical examples. The book also provides readers with a multitude of possible drug delivery systems that can be used to improve therapeutics, along with global and regulatory perspectives. This third edition contains a chapter on nanoscience and technology for drug delivery along with cutting-edge business intelligence and strategies. Written in a straightforward manner, the authors provide a global perspective on current and future advances and market opportunities. Supplying a cogent overview of the field and extensive guidance on where to get more information, it is an essential resource for anyone venturing into this area of drug development.

Drug Delivery Systems
Drug Delivery Systems

Author: Vasant V. Ranade

Publisher: CRC Press

Published: 2003-08-26

Total Pages: 464

ISBN-13: 1420040146

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Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both

Drug Delivery
Drug Delivery

Author: Binghe Wang

Publisher: John Wiley & Sons

Published: 2016-04-18

Total Pages: 740

ISBN-13: 1118833368

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Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Advanced Drug Delivery
Advanced Drug Delivery

Author: Ashim Mitra

Publisher: John Wiley & Sons

Published: 2013-08-26

Total Pages: 844

ISBN-13: 1118662849

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Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Nanopharmaceutical Advanced Delivery Systems
Nanopharmaceutical Advanced Delivery Systems

Author: Vivek Dave

Publisher: John Wiley & Sons

Published: 2020-12-29

Total Pages: 467

ISBN-13: 1119711681

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The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.