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Biopharmaceutical Production Technology

Author: Ganapathy Subramanian

Publisher: John Wiley & Sons

Published: 2012-05-14

Total Pages: 945

ISBN-13: 3527653112

Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to contain costs and improve efficiency. To adapt to these changes, industries need to review and streamline their manufacturing processes. This two volume handbook systematically addresses the key steps and challenges in the production process and provides valuable information for medium to large scale producers of biopharmaceuticals. It is divided into seven major parts: - Upstream Technologies - Protein Recovery - Advances in Process Development - Analytical Technologies - Quality Control - Process Design and Management - Changing Face of Processing With contributions by around 40 experts from academia as well as small and large biopharmaceutical companies, this unique handbook is full of first-hand knowledge on how to produce biopharmaceuticals in a cost-effective and quality-controlled manner.

Bio-Inspired Collaborative Intelligent Control and Optimization

Author: Yongsheng Ding

Publisher: Springer

Published: 2017-11-06

Total Pages: 477

ISBN-13: 9811066892

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This book presents state-of-the-art research advances in the field of biologically inspired cooperative control theories and their applications. It describes various biologically inspired cooperative control and optimization approaches and highlights real-world examples in complex industrial processes. Multidisciplinary in nature and closely integrating theory and practice, the book will be of interest to all university researchers, control engineers and graduate students in intelligent systems and control who wish to learn the core principles, methods, algorithms, and applications.

34th European Symposium on Computer Aided Process Engineering /15th International Symposium on Process Systems Engineering

Author: Flavio Manenti

Publisher: Elsevier

Published: 2024-06-27

Total Pages: 3634

ISBN-13: 0443288259

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The 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, contains the papers presented at the 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering joint event. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries. - Presents findings and discussions from the 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering joint event

27th European Symposium on Computer Aided Process Engineering

Author:

Publisher: Elsevier

Published: 2017-09-21

Total Pages: 3064

ISBN-13: 0444639705

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27th European Symposium on Computer Aided Process Engineering, Volume 40 contains the papers presented at the 27th European Society of Computer-Aided Process Engineering (ESCAPE) event held in Barcelona, October 1-5, 2017. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries. - Presents findings and discussions from the 27th European Society of Computer-Aided Process Engineering (ESCAPE) event

Biomass and Biofuels

Author: Shibu Jose

Publisher: CRC Press

Published: 2015-04-22

Total Pages: 389

ISBN-13: 1498760244

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The long-held tenets of the energy sector are being rewritten in the twenty-first century. The rise of unconventional oil and gas and of renewables is transforming our economies and improving our understanding of the distribution of the world's energy resources and their impacts. A complete knowledge of the dynamics underpinning energy markets is n

Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing

Author: Ganapathy Subramanian

Publisher: John Wiley & Sons

Published: 2021-12-20

Total Pages: 404

ISBN-13: 3527347690

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Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.

Industry 4.0 – Shaping The Future of The Digital World

Author: Paulo Jorge da Silva Bartolo

Publisher: CRC Press

Published: 2020-10-28

Total Pages: 373

ISBN-13: 1000289281

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The City of Manchester, once the birthplace of the 1st Industrial Revolution, is today a pioneering hub of the 4th Industrial Revolution (Industry 4.0), offering Industry 4.0 solutions in advanced materials, engineering, healthcare and social sciences. Indeed, the creation of some of the city’s greatest academic institutions was a direct outcome of the industrial revolution, so it was something of a homecoming that the Sustainable Smart Manufacturing (S2M) Conference was hosted by The University of Manchester in 2019. The conference was jointly organised by The University of Manchester, The University of Lisbon and The Polytechnic of Leiria – the latter two bringing in a wealth of expertise in how Industry 4.0 manifests itself in the context of sustainably evolving, deeply-rooted cities. S2M-2019 instigated the development of 61 papers selected for publication in this book on areas of Smart Manufacturing, Additive Manufacturing and Virtual Prototyping, Materials for Healthcare Applications and Circular Economy, Design Education, and Urban Spaces.

Continuous Manufacturing for the Modernization of Pharmaceutical Production

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2019-04-05

Total Pages: 69

ISBN-13: 0309487811

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On July 30-31, 2018, the National Academies of Sciences, Engineering, and Medicine held a workshop titled Continuous Manufacturing for the Modernization of Pharmaceutical Production. This workshop discussed the business and regulatory concerns associated with adopting continuous manufacturing techniques to produce biologics such as enzymes, monoclonal antibodies, and vaccines. The participants also discussed specific challenges for integration across the manufacturing system, including upstream and downstream processes, analytical techniques, and drug product development. The workshop addressed these challenges broadly across the biologics domain but focused particularly on drug categories of greatest FDA and industrial interest such as monoclonal antibodies and vaccines. This publication summarizes the presentations and discussions from the workshop.