Zinc Thiolate and Hydrosulfide Complexes with Azamacrocyclic Ligands as Versatile Enzyme Models
Author: Johannes Notni
Publisher:
Published: 2007
Total Pages: 19
ISBN-13:
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Zinc Enzyme Model Complexes with Ligands Containing a N2S Donor Set and Their Methylating Reactions
Author:
Publisher:
Published: 2004
Total Pages:
ISBN-13:
DOWNLOAD EBOOKA new tridentate and two new tripodal ligands containing a N2S donor set have been prepared in this work. These and other four selected ligands together with different thiolate co-ligands have been used for the syntheses of 47 new zinc enzyme model complexes. These complexes have been characterized and compared by IR and NMR spectroscopy, 14 of them with single crystal structure analysis. 9 of the mononuclear tetrahedral N2S2 coordinated zinc complexes have been investigated for the stepwise methylating reactions using the methylating reagent iodmethane and trimethylphosphate. The result of the reactions indicates that zinc-bound thiolates react with those methylating reagents. The methyl group transfer occurs like in the enzymatic processes.
Gold Chemistry
Author: Fabian Mohr
Publisher: John Wiley & Sons
Published: 2009-04-20
Total Pages: 425
ISBN-13: 3527320865
DOWNLOAD EBOOKWritten by world-class authors, this most recent major book on the topic highlights new and current trends as well as future directions. It is comprehensive in its scope, covering all aspects of gold chemistry -- from homogeneous to heterogeneous catalysis, from supramolecular assemblies to sensors and medicinal applications. The result is an invaluable work for both organic and inorganic chemists working in universities and industry, as well as material scientists.
Anion Receptor Chemistry
Author: Jonathan L Sessler
Publisher: Royal Society of Chemistry
Published: 2007-10-31
Total Pages: 431
ISBN-13: 1847552471
DOWNLOAD EBOOKAnion recognition plays a critical role in a range of biological processes, and a variety of receptors and carriers can be found throughout the natural world. Chemists working in the area of supramolecular chemistry have created a range of anion receptors, drawing inspiration from nature as well as their own inventive processes. This book traces the origins of anion recognition chemistry as a unique sub-field in supramolecular chemistry while illustrating the basic approaches currently being used to effect receptor design. The combination of biological overview and summary of current synthetic approaches provides a coverage that is both comprehensive and comprehensible. First, the authors detail the key design motifs that have been used to generate synthetic receptors and which are likely to provide the basis for further developments. They also highlight briefly some of the features that are present in naturally occurring anion recognition and transport systems and summarise the applications of anion recognition chemistry. Providing as it does a detailed review for practitioners in the field and a concise introduction to the topic for newcomers, Anion Receptor Chemistry reflects the current state of the art. Fully referenced and illustrated in colour, it is a welcome addition to the literature.
Anion Sensing
Author: Eric V. Anslyn
Publisher: Springer Science & Business Media
Published: 2005-05-06
Total Pages: 252
ISBN-13: 9783540232476
DOWNLOAD EBOOKwith contributions by numerous experts
The Chemistry and Biology of Nitroxyl (HNO)
Author: Fabio Doctorovich
Publisher: Elsevier
Published: 2016-09-01
Total Pages: 425
ISBN-13: 0128011645
DOWNLOAD EBOOKThe Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia
Lanthanide Luminescence
Author: Pekka Hänninen
Publisher: Springer Science & Business Media
Published: 2011-06-21
Total Pages: 392
ISBN-13: 3642210236
DOWNLOAD EBOOKLanthanides have fascinated scientists for more than two centuries now, and since efficient separation techniques were established roughly 50 years ago, they have increasingly found their way into industrial exploitation and our everyday lives. Numerous applications are based on their unique luminescent properties, which are highlighted in this volume. It presents established knowledge about the photophysical basics, relevant lanthanide probes or materials, and describes instrumentation-related aspects including chemical and physical sensors. The uses of lanthanides in bioanalysis and medicine are outlined, such as assays for in vitro diagnostics and research. All chapters were compiled by renowned scientists with a broad audience in mind, providing both beginners in the field and advanced researchers with comprehensive information on on the given subject.
Metals in Cells
Author: Valeria Culotta
Publisher: John Wiley & Sons
Published: 2016-03-16
Total Pages: 608
ISBN-13: 1118636864
DOWNLOAD EBOOKOver the last three decades a lot of research on the role of metals in biochemistry and medicine has been done. As a result many structures of biomolecules with metals have been characterized and medicinal chemistry studied the effects of metal containing drugs. This new book (from the EIBC Book Series) covers recent advances made by top researchers in the field of metals in cells [the “metallome”] and include: regulated metal ion uptake and trafficking, sensing of metals within cells and across tissues, and identification of the vast cellular factors designed to orchestrate assembly of metal cofactor sites while minimizing toxic side reactions of metals. In addition, it features aspects of metals in disease, including the role of metals in neuro-degeneration, liver disease, and inflammation, as a way to highlight the detrimental effects of mishandling of metal trafficking and response to "foreign" metals. With the breadth of our recently acquired understanding of metals in cells, a book that features key aspects of cellular handling of inorganic elements is both timely and important. At this point in our understanding, it is worthwhile to step back and take an expansive view of how far our understanding has come, while also highlighting how much we still do not know. The content from this book will publish online, as part of EIBC in December 2013, find out more about the Encyclopedia of Inorganic and Bioinorganic Chemistry, the essential online resource for researchers and students working in all areas of inorganic and bioinorganic chemistry.
Anion Recognition in Supramolecular Chemistry
Author: Philip A. Gale
Publisher: Springer
Published: 2011-05-26
Total Pages: 378
ISBN-13: 3642154441
DOWNLOAD EBOOKBrett M. Rambo ∙ Eric S. Silver ∙ Christopher W. Bielawski ∙ Jonathan L. Sessler Covalent Polymers Containing Discrete Heterocyclic Anion Receptors Philip A. Gale ∙ Chang-Hee Lee Calix[n]pyrroles as Anion and Ion-Pair Complexants Wim Dehaen Calix[n]phyrins: Synthesis and Anion Recognition Hiromitsu Maeda Acyclic Oligopyrrolic Anion Receptors Jeffery T. Davis Anion Binding and Transport by Prodigiosin and Its Analogs Hemraj Juwarker ∙ Jae-min Suk ∙ Kyu-Sung Jeong Indoles and Related Heterocycles Pavel Anzenbacher Jr. Pyrrole-Based Anion Sensors, Part I: Colorimetric Sensors Pavel Anzenbacher Jr. Pyrrole-Based Anion Sensors, Part II: Fluorescence, Luminescence, and Electrochemical Sensors Ermitas Alcalde ∙ Immaculada Dinarès ∙ Neus Mesquida Imidazolium-Based Receptors Nathan L. Kilah ∙ Paul D. Beer Pyridine and Pyridinium-Based Anion Receptors Kevin P. McDonald ∙ Yuran Hua ∙ Amar H. Flood 1,2,3-Triazoles and the Expanding Utility of Charge Neutral CHlllAnion Interactions
Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells
Author: Kenneth Kam-Wing Lo
Publisher: Academic Press
Published: 2016-12-30
Total Pages: 408
ISBN-13: 012803887X
DOWNLOAD EBOOKInorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells Foscuses on the fundamentals and their potential therapeutic and diagnostic applications Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents
