This fascinating study examines the rise of American molecular biology to disciplinary dominance, focusing on the period between 1930 and the elucidation of DNA structure in the mid 1950s. Research undertaken during this period, with its focus on genetic structure and function, endowed scientists with then unprecedented power over life. By viewing the new biology as both a scientific and cultural enterprise, Lily E. Kay shows that the growth of molecular biology was a result of systematic efforts by key scientists and their sponsors to direct the development of biological research toward a shared vision of science and society. She analyzes the motivations and mechanisms empowering this vision by focusing on two key institutions: Caltech and its sponsor, the Rockefeller Foundation. Her study explores a number of vital, sometimes controversial topics, among them the role of private power centers in shaping scientific agenda, and the political dimensions of "pure" research. It also advances a sobering argument: the cognitive and social groundwork for genetic engineering and human genome projects was laid by the American architects of molecular biology during these early decades of the project. This book will be of interest to molecular biologists, historians, sociologists, and the general reader alike.
Science is often portrayed as an obscure, difficult discipline, governed by elite researchers and inaccessible to the general public. In this riveting, inspiring new book, preeminent astrophysicist Martin Rees overturns this view, urging improved communication between researchers and laypeople. In order to shape debates over healthcare, energy policy, space travel, and other vital issues, ordinary citizens must develop a "feel" for science--the one truly global culture--and engage directly with research rather than relying on pundits' and politicians' interpretations. Recognized as an expert on the political and ethical impact of science, Rees demonstrate show we must solve the new challenges we face--from population growth to climate change--by devising strategies with a long-term, global perspective. In the process, he offers insights into the prospects for future discoveries while also explaining science's intrinsic limits. Just as importantly, Rees reminds us that science should be a source of pleasure and wonder for specialists and nonspecialists alike.
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
In recent years, planetary science has seen a tremendous growth in new knowledge. Deposits of water ice exist at the Moon's poles. Discoveries on the surface of Mars point to an early warm wet climate, and perhaps conditions under which life could have emerged. Liquid methane rain falls on Saturn's moon Titan, creating rivers, lakes, and geologic landscapes with uncanny resemblances to Earth's. Vision and Voyages for Planetary Science in the Decade 2013-2022 surveys the current state of knowledge of the solar system and recommends a suite of planetary science flagship missions for the decade 2013-2022 that could provide a steady stream of important new discoveries about the solar system. Research priorities defined in the report were selected through a rigorous review that included input from five expert panels. NASA's highest priority large mission should be the Mars Astrobiology Explorer Cacher (MAX-C), a mission to Mars that could help determine whether the planet ever supported life and could also help answer questions about its geologic and climatic history. Other projects should include a mission to Jupiter's icy moon Europa and its subsurface ocean, and the Uranus Orbiter and Probe mission to investigate that planet's interior structure, atmosphere, and composition. For medium-size missions, Vision and Voyages for Planetary Science in the Decade 2013-2022 recommends that NASA select two new missions to be included in its New Frontiers program, which explores the solar system with frequent, mid-size spacecraft missions. If NASA cannot stay within budget for any of these proposed flagship projects, it should focus on smaller, less expensive missions first. Vision and Voyages for Planetary Science in the Decade 2013-2022 suggests that the National Science Foundation expand its funding for existing laboratories and establish new facilities as needed. It also recommends that the program enlist the participation of international partners. This report is a vital resource for government agencies supporting space science, the planetary science community, and the public.
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