Gastritis and Gastric Cancer

Gastritis and Gastric Cancer

Author: Paola Tonino

Publisher:

Published: 2011

Total Pages: 310

ISBN-13: 9789535164838

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This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.


Gastritis and Gastric Cancer

Gastritis and Gastric Cancer

Author: Paola Tonino

Publisher: BoD – Books on Demand

Published: 2011-09-15

Total Pages: 312

ISBN-13: 9533073756

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This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.


Morson and Dawson's Gastrointestinal Pathology

Morson and Dawson's Gastrointestinal Pathology

Author: David W. Day

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 704

ISBN-13: 047075530X

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Morson and Dawson's Gastrointestinal Pathology is one of the 'Gold Standards' of pathology textbooks. It has been completely revised to incorporate the latest advances in this rapidly evolving field including the developments in gastric cancer and Helicobacter pylori and the revised classification of other common gastrointestinal conditions. This new edition features a wealth of new material presented in full colour for the first time.


Trends in Helicobacter pylori Infection

Trends in Helicobacter pylori Infection

Author: Bruna Maria Roesler

Publisher: BoD – Books on Demand

Published: 2014-04-03

Total Pages: 394

ISBN-13: 9535112392

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Helicobacter pylori is a universally distributed bacterium which affects more than half of the world population. The infection is associated with the development of various diseases of the upper gastrointestinal tract, besides extradigestive diseases. This book is a comprehensive overview of contributors on H. pylori infection in several areas. Its chapters were divided into sections concerning general aspects of H. pylori infection, immunopathology and genetic diversity, questions regarding possible routes of bacterium transmission, the importance of the strains characteristics in the development of gastric cancer and the possibilities of prevention, H. pylori infection in children, the possible association between its infection and extradigestive diseases, and the principal therapeutic regimens of bacterium eradication, considering the antimicrobial resistance.


Current Topics in Gastritis

Current Topics in Gastritis

Author: Gyula Mozsik

Publisher: BoD – Books on Demand

Published: 2013-01-16

Total Pages: 278

ISBN-13: 9535109073

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Gastritis, as a medical term, exists for the last 150 years, however, terminology and etiology (including the prognosis ) has changed. Gastritis related medical problems are in the focus of different sub-disciplines: internists , gastroenterologists, pathologists, immunologists, bacteriologists, genetics, biologists etc. After the publications by Marshall and Warren most of the clinicians accepted only the etiopathological role of Helicobacter pylori in the development of gastric and duodenal ulcer , as well as in the gastric cancer. This book presents chapters abou the history of gastritis terminology, animal models, epidemiology, new gastric mucosal endogenous defensive neural mechanism (capsaicin-sinsitive afferentation), different research and clinical methods applied to the background studies and the molecular pathology, biochemistry and genetics involved in the pathways from Helicobacter pylori infection to development of gastric cancer. Intended audience of this book are internists, gastroenterologists, pathologists, bacteriologists, pharmacologists, genetics, biologists , immunologists and other interested researchers.


Staging Laparoscopy

Staging Laparoscopy

Author: P. Hohenberger

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 206

ISBN-13: 3642562906

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Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.


Geriatric Gastroenterology

Geriatric Gastroenterology

Author: C. S. Pitchumoni

Publisher: Springer Science & Business Media

Published: 2012-07-26

Total Pages: 660

ISBN-13: 1441916237

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As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.


Perioperative Chemotherapy

Perioperative Chemotherapy

Author: U. Metzger

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 170

ISBN-13: 3642824323

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One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.


Healthy Stomach Initiative

Healthy Stomach Initiative

Author: P. Malfertheiner

Publisher: S. Karger AG (Switzerland)

Published: 2014-04-17

Total Pages: 0

ISBN-13: 9783318026320

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This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in Gastroenterology. Special topic issues are included in the subscription.


Helicobacter pylori and Gastroduodenal Pathology

Helicobacter pylori and Gastroduodenal Pathology

Author: Jose M. Pajares

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 401

ISBN-13: 3642774865

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In the rapidly evolving field of Helicobacter infection new data on pathogenetic and pathophysiological mechanism have appeared. New methods which will be more sensitive and specific in the diagnosis of the infection are being developed and in this proceedings the first attempt using PCR technology is published. From the clinical point of view, a challenging aspect that needs clarification, is the observation which suggests an appearance of a correlation between the presence of the bacteria and abdominal pain and other symptoms in children whereas in old age no such correlation is evident. The relationship of H. pylori and gastric cancer is studied with histopathological data and epidemiological approaches. On the treatment side schemes using short courses and new antibiotic combinations are being investigated and preliminary data are reported.