Variant Haemoglobins
Variant Haemoglobins

Author: Barbara J. Bain

Publisher: John Wiley & Sons

Published: 2011-06-28

Total Pages: 548

ISBN-13: 1444347675

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Variant Haemoglobins – A Guide to Identification is based on the premise that any single diagnostic technique offers only a very provisional identification of a variant haemoglobin. In routine diagnostic practice two techniques are needed as a minimum, with the results being interpreted in the light of the clinical details, blood count, blood film and ethnic origin. This book covers 150 normal and variant haemoglobins that have been studied and carefully documented. Variant Haemoglobins has four introductory chapters followed by an invaluable atlas. The introductory chapters cover the genetics of haemoglobin synthesis the principles of tests employed for identification common haemoglobins of major clinical or diagnostic importance thalassaemias and related conditions The atlas section comprises 170 full colour pages in which each variant haemoglobin or combination of haemoglobins is illustrated by cellulose acetate electrophoresis at alkaline pH, agarose gel electrophoresis at acid pH, isoelectric focusing and one or more HPLC traces. For ease of reference, the atlas pages are arranged according to the retention time of each haemoglobin on HPLC, this becoming increasingly the primary technique employed in haemoglobin identification. Bringing a mix of necessary scientific expertise and clinical knowledge, each author has more than 30 years experience in the diagnosis of variant haemoglobins. Providing otherwise unavailable information, this unique and practical guide is illustrated with over 700 high quality colour digital images plus flow charts and line diagrams covers common and important haemoglobin variants, in addition to many rarer ones is an essential reference source for diagnosis in the haematology laboratory A remarkably useful book, Variant Haemoglobins will be valuable for haematopathologists, clinical and laboratory haematologists in practice and in training and all laboratory staff involved in haemoglobinopathy diagnosis.

Variant Haemoglobins
Variant Haemoglobins

Author: Barbara J. Bain

Publisher: Wiley-Blackwell

Published: 2011-01-04

Total Pages: 0

ISBN-13: 9781405167154

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Variant Haemoglobins – A Guide to Identification is based on the premise that any single diagnostic technique offers only a very provisional identification of a variant haemoglobin. In routine diagnostic practice two techniques are needed as a minimum, with the results being interpreted in the light of the clinical details, blood count, blood film and ethnic origin. This book covers 150 normal and variant haemoglobins that have been studied and carefully documented. Variant Haemoglobins has four introductory chapters followed by an invaluable atlas. The introductory chapters cover the genetics of haemoglobin synthesis the principles of tests employed for identification common haemoglobins of major clinical or diagnostic importance thalassaemias and related conditions The atlas section comprises 170 full colour pages in which each variant haemoglobin or combination of haemoglobins is illustrated by cellulose acetate electrophoresis at alkaline pH, agarose gel electrophoresis at acid pH, isoelectric focusing and one or more HPLC traces. For ease of reference, the atlas pages are arranged according to the retention time of each haemoglobin on HPLC, this becoming increasingly the primary technique employed in haemoglobin identification. Bringing a mix of necessary scientific expertise and clinical knowledge, each author has more than 30 years experience in the diagnosis of variant haemoglobins. Providing otherwise unavailable information, this unique and practical guide is illustrated with over 700 high quality colour digital images plus flow charts and line diagrams covers common and important haemoglobin variants, in addition to many rarer ones is an essential reference source for diagnosis in the haematology laboratory A remarkably useful book, Variant Haemoglobins will be valuable for haematopathologists, clinical and laboratory haematologists in practice and in training and all laboratory staff involved in haemoglobinopathy diagnosis.

Disorders of Hemoglobin
Disorders of Hemoglobin

Author: Martin H. Steinberg

Publisher: Cambridge University Press

Published: 2009-08-17

Total Pages: 883

ISBN-13: 0521875196

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Completely revised new edition of the definitive reference on disorders of hemoglobin.

Haemoglobinopathy Diagnosis
Haemoglobinopathy Diagnosis

Author: Barbara J. Bain

Publisher: John Wiley & Sons

Published: 2020-02-28

Total Pages: 452

ISBN-13: 1119579996

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An updated, essential guide for the laboratory diagnosis of haemoglobin disorders This revised and updated third edition of Haemoglobinopathy Diagnosis offers a comprehensive review of the practical information needed for an understanding of the laboratory diagnosis of haemoglobin disorders. Written in a concise and approachable format, the book includes an overview of clinical and laboratory features of these disorders. The author focuses on the selection, performance, and interpretation of the tests that are offered by the majority of diagnostic laboratories. The book also explains when more specialist tests are required and explores what specialist referral centres will accomplish. The information on diagnosis is set in a clinical context. The third edition is written by a leading haematologist with a reputation for educational excellence. Designed as a practical resource, the book is filled with illustrative examples and helpful questions that can aide in the retention of the material presented. Additionally, the author includes information on the most recent advances in the field. This important text: • Contains a practical, highly illustrated, approach to the laboratory diagnosis of haemoglobin disorders • Includes “test-yourself” questions and provides an indispensable tool for learning and teaching • Presents new material on antenatal screening/prenatal diagnostic services • Offers myriad self-assessment case studies that are ideal for the trainee Written for trainees and residents in haematology, practicing haematologists, and laboratory scientists, Haemoglobinopathy Diagnosis is an essential reference and learning tool that provides a clear basis for understanding the diagnosis of haemoglobin disorders.

Prevention of Thalassaemias and Other Haemoglobin Disorders
Prevention of Thalassaemias and Other Haemoglobin Disorders

Author: Galanello Renzo

Publisher:

Published: 2003

Total Pages: 190

ISBN-13: 9789963623396

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Volume 1 of the Prevention Book presents the principles of a programme for the prevention of the thalassaemia and other haemoglobin disorders, including a description of the various types of disorders requiring prenatal diagnosis, the strategies used for carrier screening, and a number of annexes listing upto date epidemiological and mutation data on thalassaemia. This book was written for use in combination with Volume 2, which describes many of the laboratory protocols in great detail.

The Thalassaemia Syndromes
The Thalassaemia Syndromes

Author: David J. Weatherall

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 864

ISBN-13: 0470695943

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In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years.

The Obstetric Hematology Manual
The Obstetric Hematology Manual

Author: Sue Pavord

Publisher: Cambridge University Press

Published: 2018-02-08

Total Pages: 362

ISBN-13: 1108548377

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Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and other Body Fluid Proteins
Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and other Body Fluid Proteins

Author: Ulrich Hoeger

Publisher: Springer Nature

Published: 2020-03-18

Total Pages: 527

ISBN-13: 3030417697

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This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.

Pediatric Emergency Medicine
Pediatric Emergency Medicine

Author: Jill M. Baren

Publisher: Elsevier Health Sciences

Published: 2008-01-01

Total Pages: 1352

ISBN-13: 1416000879

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This authoritative reference equips you with the essential knowledge to provide comprehensive and effective care to children in an emergency setting. From age-specific diagnoses and chief complaints through developmental considerations and psychosocial issues, this text guides you through the full range of medical and surgical conditions commonly encountered when treating pediatric emergencies. The use of full color throughout, diagnostic algorithms, text boxes, charts, clinical pearls and pitfalls, and other visual features ensure the book will make crucial clinical information easy to find and apply. Tap into expert guidance on all aspects of pediatric emergency medicine, from the physical exam and usual and unusual presentations through to disposition criteria and transfer issues. Access step-by-step guidance on administering critical life support interventions and providing effective diagnostic and therapeutic ambulatory care. Quickly review specific treatment protocols for various emergency settings, including general emergency departments, community hospitals, tertiary care centers, EMS and transport, and triage. Find information fast with or without a known diagnosis, with content organized both by chief complaints and by specific diagnoses. Better understand how problems present differently in infants, children, and adolescents with age-specific diagnoses. Identify and manage the psychosocial issues surrounding pediatric patients, including major depression and suicidality, sexual and physical abuse, child neglect, and violence. Easily absorb key information with the aid of text boxes, algorithms, clinical pearls, and pitfalls. Retrieve information easily with a consistent templated format.