Designing Clinical Research

Designing Clinical Research

Author: Stephen B. Hulley

Publisher: Lippincott Williams & Wilkins

Published: 2011-11-30

Total Pages: 388

ISBN-13: 1451165854

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Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.


Hands-on Rust

Hands-on Rust

Author: Herbert Wolverson

Publisher: Pragmatic Bookshelf

Published: 2021-06-30

Total Pages: 446

ISBN-13: 1680508806

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Rust is an exciting new programming language combining the power of C with memory safety, fearless concurrency, and productivity boosters - and what better way to learn than by making games. Each chapter in this book presents hands-on, practical projects ranging from "Hello, World" to building a full dungeon crawler game. With this book, you'll learn game development skills applicable to other engines, including Unity and Unreal. Rust is an exciting programming language combining the power of C with memory safety, fearless concurrency, and productivity boosters. With Rust, you have a shiny new playground where your game ideas can flourish. Each chapter in this book presents hands-on, practical projects that take you on a journey from "Hello, World" to building a full dungeon crawler game. Start by setting up Rust and getting comfortable with your development environment. Learn the language basics with practical examples as you make your own version of Flappy Bird. Discover what it takes to randomly generate dungeons and populate them with monsters as you build a complete dungeon crawl game. Run game systems concurrently for high-performance and fast game-play, while retaining the ability to debug your program. Unleash your creativity with magical items, tougher monsters, and intricate dungeon design. Add layered graphics and polish your game with style. What You Need: A computer running Windows 10, Linux, or Mac OS X.A text editor, such as Visual Studio Code.A video card and drivers capable of running OpenGL 3.2.


Deep Learning in Biology and Medicine

Deep Learning in Biology and Medicine

Author: Davide Bacciu

Publisher: World Scientific Publishing Europe Limited

Published: 2021

Total Pages: 0

ISBN-13: 9781800610934

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Biology, medicine and biochemistry have become data-centric fields for which Deep Learning methods are delivering groundbreaking results. Addressing high impact challenges, Deep Learning in Biology and Medicine provides an accessible and organic collection of Deep Learning essays on bioinformatics and medicine. It caters for a wide readership, ranging from machine learning practitioners and data scientists seeking methodological knowledge to address biomedical applications, to life science specialists in search of a gentle reference for advanced data analytics.With contributions from internationally renowned experts, the book covers foundational methodologies in a wide spectrum of life sciences applications, including electronic health record processing, diagnostic imaging, text processing, as well as omics-data processing. This survey of consolidated problems is complemented by a selection of advanced applications, including cheminformatics and biomedical interaction network analysis. A modern and mindful approach to the use of data-driven methodologies in the life sciences also requires careful consideration of the associated societal, ethical, legal and transparency challenges, which are covered in the concluding chapters of this book.


Unconventional Models of Computation

Unconventional Models of Computation

Author: Cristian Calude

Publisher: Springer

Published: 2003-06-30

Total Pages: 339

ISBN-13: 3540458336

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This book constitutes the refereed proceedings of the Third International Conference on Unconventional Models of Computation, UMC 2002, held in Kobe, Japan in October 2002.The 18 revised full papers presented together with eight invited full papers were carefully reviewed and selected from 36 submissions. All major areas of unconventinal computing models are covered, especially quantum computing, DNA computing, membrane computing, cellular computing, and possibilities to break Turing's barrier. The authors address theoretical aspects, practical implementations, as well as philosophical reflections.


Carpal Tunnel Syndrome and Related Median Neuropathies

Carpal Tunnel Syndrome and Related Median Neuropathies

Author: Scott F. M. Duncan

Publisher: Springer

Published: 2017-07-03

Total Pages: 309

ISBN-13: 3319570102

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Practical and user-friendly, this text provides the orthopedic and hand surgeon with all the essential information for diagnosing and treating carpal tunnel syndrome (CTS) and other median neuropathies of the hand and wrist, with special emphasis on challenges and complications. Organized to allow for easy searching of specific subject matter, opening chapters discuss anatomy of the median nerve, history and pathophysiology of CTS, clinical presentation and diagnosis, including imaging, and severity scoring. Presentation of various treatment strategies follows, both non-operative and surgical, including open and endoscopic techniques and revision surgery, incomplete release, transection, use of the reverse radial forearm flap, vein wrap, synovial wrap, and microneurolysis. Other median neuropathies are discussed as well, including neuromas and stimulation for chronic median nerve pain. Generously illustrated, Carpal Tunnel Syndrome and Related Median Neuropathies is a valuable resource for orthopedic and hand surgeons on the evaluation and treatment of complications and complexities arising from carpal tunnel syndrome and surgery.


Small-Animal SPECT Imaging

Small-Animal SPECT Imaging

Author: Matthew A. Kupinski

Publisher: Springer Science & Business Media

Published: 2007-05-27

Total Pages: 304

ISBN-13: 0387252940

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Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.


Rust in Action

Rust in Action

Author: Tim McNamara

Publisher: Simon and Schuster

Published: 2021-09-07

Total Pages: 454

ISBN-13: 163835622X

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"This well-written book will help you make the most of what Rust has to offer." - Ramnivas Laddad, author of AspectJ in Action Rust in Action is a hands-on guide to systems programming with Rust. Written for inquisitive programmers, it presents real-world use cases that go far beyond syntax and structure. Summary Rust in Action introduces the Rust programming language by exploring numerous systems programming concepts and techniques. You'll be learning Rust by delving into how computers work under the hood. You'll find yourself playing with persistent storage, memory, networking and even tinkering with CPU instructions. The book takes you through using Rust to extend other applications and teaches you tricks to write blindingly fast code. You'll also discover parallel and concurrent programming. Filled to the brim with real-life use cases and scenarios, you'll go beyond the Rust syntax and see what Rust has to offer in real-world use cases. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the technology Rust is the perfect language for systems programming. It delivers the low-level power of C along with rock-solid safety features that let you code fearlessly. Ideal for applications requiring concurrency, Rust programs are compact, readable, and blazingly fast. Best of all, Rust’s famously smart compiler helps you avoid even subtle coding errors. About the book Rust in Action is a hands-on guide to systems programming with Rust. Written for inquisitive programmers, it presents real-world use cases that go far beyond syntax and structure. You’ll explore Rust implementations for file manipulation, networking, and kernel-level programming and discover awesome techniques for parallelism and concurrency. Along the way, you’ll master Rust’s unique borrow checker model for memory management without a garbage collector. What's inside Elementary to advanced Rust programming Practical examples from systems programming Command-line, graphical and networked applications About the reader For intermediate programmers. No previous experience with Rust required. About the author Tim McNamara uses Rust to build data processing pipelines and generative art. He is an expert in natural language processing and data engineering. Table of Contents 1 Introducing Rust PART 1 RUST LANGUAGE DISTINCTIVES 2 Language foundations 3 Compound data types 4 Lifetimes, ownership, and borrowing PART 2 DEMYSTIFYING SYSTEMS PROGRAMMING 5 Data in depth 6 Memory 7 Files and storage 8 Networking 9 Time and timekeeping 10 Processes, threads, and containers 11 Kernel 12 Signals, interrupts, and exceptions


Chronobiotechnology and Chronobiological Engineering

Chronobiotechnology and Chronobiological Engineering

Author: L.E. Scheving

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 475

ISBN-13: 9400935471

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High blood pressure (BP) (with fats and smoking) is one of the three roots of cardio-cerebro-renovascular disease affecting up to 25% of the adult population. Hence, high blood pressure should be recognized and treated, to reduce any complications and prolong life, as noted by Michael Weber of the Veterans Administration Hospital in Long Beach, California. He further emphasizes the need for monitoring before one starts the treatment of high blood pressure. Indeed, he refers to the results of the Australian study on mild hypertension with a large percentage of placebo responders and rightly suggests that many people are treated who should not be because of 'white-coat-associated high blood pressure'. He also points to the lack of standardization of techniques for data analysis and of methods of BP measurement. Ambulatory monitoring under usual condi tions without concomitant recording of events does not allow even a qualitative assessment of the impact of varying stimuli, in weber's opinion.