Machine Learning and Knowledge Discovery in Databases
Machine Learning and Knowledge Discovery in Databases

Author: Wray Buntine

Publisher: Springer Science & Business Media

Published: 2009-09-03

Total Pages: 787

ISBN-13: 3642041736

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This book constitutes the refereed proceedings of the joint conference on Machine Learning and Knowledge Discovery in Databases: ECML PKDD 2009, held in Bled, Slovenia, in September 2009. The 106 papers presented in two volumes, together with 5 invited talks, were carefully reviewed and selected from 422 paper submissions. In addition to the regular papers the volume contains 14 abstracts of papers appearing in full version in the Machine Learning Journal and the Knowledge Discovery and Databases Journal of Springer. The conference intends to provide an international forum for the discussion of the latest high quality research results in all areas related to machine learning and knowledge discovery in databases. The topics addressed are application of machine learning and data mining methods to real-world problems, particularly exploratory research that describes novel learning and mining tasks and applications requiring non-standard techniques.

CRISPR and RNAi Systems
CRISPR and RNAi Systems

Author: Kamel A Abd-Elsalam

Publisher: Elsevier

Published: 2021-02-27

Total Pages: 842

ISBN-13: 0128219114

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Plants are vulnerable to pathogens including fungi, bacteria, and viruses, which cause critical problems and deficits. Crop protection by plant breeding delivers a promising solution with no obvious effect on human health or the local ecosystem. Crop improvement has been the most powerful approach for producing unique crop cultivars since domestication occurred, making possible the main innovations in feeding the globe and community development. Genome editing is one of the genetic devices that can be implemented, and disease resistance is frequently cited as the most encouraging application of CRISPR/Cas9 technology in agriculture. Nanobiotechnology has harnessed the power of genome editing to develop agricultural crops. Nanosized DNA or RNA nanotechnology approaches could contribute to raising the stability and performance of CRISPR guide RNAs. This book brings together the latest research in these areas. CRISPR and RNAi Systems: Nanobiotechnology Approaches to Plant Breeding and Protection presents a complete understanding of the RNAi and CRISPR/Cas9 techniques for controlling mycotoxins, fighting plant nematodes, and detecting plant pathogens. CRISPR/Cas genome editing enables efficient targeted modification in most crops, thus promising to accelerate crop improvement. CRISPR/Cas9 can be used for management of plant insects, and various plant pathogens. The book is an important reference source for both plant scientists and environmental scientists who want to understand how nano biotechnologically based approaches are being used to create more efficient plant protection and plant breeding systems. - Shows how nanotechnology is being used as the basis for new solutions for more efficient plant breeding and plant protection - Outlines the major techniques and applications of both CRISPR and RNAi technologies - Assesses the major challenges of escalating these technologies on a mass scale

Plant Systems Biology
Plant Systems Biology

Author: Sacha Baginsky

Publisher: Springer Science & Business Media

Published: 2007-06-25

Total Pages: 362

ISBN-13: 376437439X

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This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.

Omics and Plant Abiotic Stress Tolerance
Omics and Plant Abiotic Stress Tolerance

Author: Narenda Tuteja

Publisher: Bentham Science Publishers

Published: 2011

Total Pages: 185

ISBN-13: 1608050580

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"Multiple biotic and abiotic environmental factors may constitute stresses that affect plant growth and yield in crop species. Advances in plant physiology, genetics, and molecular biology have greatly improved our understanding of plant responses to stres"

Review of the Department of Energy's Genomics: GTL Program
Review of the Department of Energy's Genomics: GTL Program

Author: National Research Council

Publisher: National Academies Press

Published: 2006-04-19

Total Pages: 102

ISBN-13: 0309180716

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The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.

Plant Developmental Biology
Plant Developmental Biology

Author: Lars Hennig

Publisher: Humana

Published: 2016-08-23

Total Pages: 448

ISBN-13: 9781493957347

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Plants come in myriads of shapes and colors, and the beauty of plants has fascinated mankind for thousands of years. Long before Mendel discovered the laws of heritab- ity and Darwin developed his theory on evolution, the affection for ornamental plants led people to select alleles that establish novel plant forms. Today, plant developmental biology tries to discover the mechanisms that control the establishment of specialized cell types, tissues, and organs from the fertilized egg during a plant’s life. Although the underlying processes of cell proliferation and differentiation are similar in plants and a- mals, plants are different because their development is usually open, and its outcome is not the faithful repetition of a general plan but is strongly in?uenced by environm- tal conditions. In the last few decades, plant developmental biology has pinpointed a large number of developmental regulators and their interactions and the mechanisms that govern plant development start to emerge. In part, this progress was enabled by the advance of powerful molecular tools for a few model species, most importantly Arabidopsis. This volume of the Methods in Molecular Biology series provides a collection of protocols for many of the common experimental approaches in plant developmental bi- ogy. All chapters are written in the same format as that used in the Methods in Molecular TM Biology series. Each chapter opens with a description of the basic theory behind the method being described.

Feedback Control in Systems Biology
Feedback Control in Systems Biology

Author: Carlo Cosentino

Publisher: CRC Press

Published: 2011-10-17

Total Pages: 298

ISBN-13: 1439816905

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Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty—such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedback, and research in systems biology over the past decade has shown that feedback control systems are widely found in biology. As an increasing number of researchers in the life sciences become interested in control-theoretic ideas such as feedback, stability, noise and disturbance attenuation, and robustness, there is a need for a text that explains feedback control as it applies to biological systems. Written by established researchers in both control engineering and systems biology, Feedback Control in Systems Biology explains how feedback control concepts can be applied to systems biology. Filling the need for a text on control theory for systems biologists, it provides an overview of relevant ideas and methods from control engineering and illustrates their application to the analysis of biological systems with case studies in cellular and molecular biology. Control Theory for Systems Biologists The book focuses on the fundamental concepts used to analyze the effects of feedback in biological control systems, rather than the control system design methods that form the core of most control textbooks. In addition, the authors do not assume that readers are familiar with control theory. They focus on "control applications" such as metabolic and gene-regulatory networks rather than aircraft, robots, or engines, and on mathematical models derived from classical reaction kinetics rather than classical mechanics. Another significant feature of the book is that it discusses nonlinear systems, an understanding of which is crucial for systems biologists because of the highly nonlinear nature of biological systems. The authors cover tools and techniques for the analysis of linear and nonlinear systems; negative and positive feedback; robustness analysis methods; techniques for the reverse-engineering of biological interaction networks; and the analysis of stochastic biological control systems. They also identify new research directions for control theory inspired by the dynamic characteristics of biological systems. A valuable reference for researchers, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.

Bioinformatics for Plant Research and Crop Breeding
Bioinformatics for Plant Research and Crop Breeding

Author: Jen-Tsung Chen

Publisher: John Wiley & Sons

Published: 2024-07-22

Total Pages: 612

ISBN-13: 1394209959

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Explore and advance bioinformatics and systems biology tools for crop breeding programs in this practical resource for researchers Plant biology and crop breeding have produced an immense amount of data in recent years, from genomics to interactome and beyond. Bioinformatics tools, which aim at analyzing the vast quantities of data produced by biological research and processes, have developed at a rapid pace to meet the challenges of this vast data trove. The resulting field of bioinformatics and systems biology is producing increasingly rich and transformative research. Bioinformatics for Plant Research and Crop Breeding offers an overview of this field, its recent advances, and its wider applications. Drawing on a range of analytical and data-science tools, its foundation on an in-silico platform acquired multi-omics makes it indispensable for scientists and researchers alike. It promises to become ever more relevant as new techniques for generating and organizing data continue to transform the field. Bioinformatics for Plant Research and Crop Breeding readers will also find: A focus on emerging trends in plant science, sustainable agriculture, and global food security Detailed discussion of topics including plant diversity, plant stresses, nanotechnology in agriculture, and many others Applications incorporating artificial intelligence, machine learning, deep learning and more Bioinformatics for Plant Research and Crop Breeding is ideal for researchers and scientists interested in the potential of OMICs, and bioinformatic tools to aid and develop crop improvement programs.

A New Biology for the 21st Century
A New Biology for the 21st Century

Author: National Research Council

Publisher: National Academies Press

Published: 2009-11-20

Total Pages: 113

ISBN-13: 0309147867

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Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach-one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers-be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.

Plant Resistance to Viruses
Plant Resistance to Viruses

Author: David Evered

Publisher: John Wiley & Sons

Published: 2008-04-30

Total Pages: 226

ISBN-13: 0470513578

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Concern about the environmental consequences of the widespread use of pesticides has increased, and evidence of pesticide-resistant virus vectors have continued to emerge. This volume presents a timely survey of the mechanisms of plant resistance and examines current developments in breeding for resistance, with particular emphasis on advances in genetic engineering which allow for the incorporation of viral genetic material into plants. Discusses the mechanisms of innate resistance in strains of tobacco, tomato, and cowpea; various aspects of induced resistance, including the characterization and roles of the pathogenesis-related proteins; antiviral substances and their comparison with interferon; and cross-protection between plant virus strains. Also presents several papers which evaluate the status of genetic engineering as it relates to breeding resistant plants. Among these are discussions of the potential use of plant viruses as gene vectors, gene coding for viral coat protein, satellite RNA, and antisense RNA, and practical issues such as the durability of resistant crop plants in the field.