Reviewing current studies and previously unpublished research from leading laboratories around the world, Unravelling Lipid Metabolism With Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. It provides an extensive overview of statistical approaches to microarray data, as well as discussions on how microarrays can be used to understand the role of lipids in the initiation or prevention of disorders such as cancer, diabetes, and obesity. Of particular note is a chapter by the only group known to study the effect of lipids on transcriptomics in multiple brain regions.
Following the successful and proven concept used in "Bioactive Heterocyclic Compound Classes" by the same editors, this book is the first to present approved pharmaceutical and agrochemical compounds classified by their carboxylic acid functionality in one handy volume. Each of the around 40 chapters describes one or two typical syntheses of a specific compound class and provides concise information on the history of development, mode of action, biological activity and field of application, as well as structure-activity relationships. In addition, similarities and differences between pharmaceuticals and agrochemicals are discussed in the introduction. Written by a team of experts in the field, this is a useful reference for researchers in academia and chemical or pharmaceutical companies working in the field of total synthesis and natural product chemistry, drug development, and crop protection research.
Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a means to attain a systems level understanding of complex biological systems.
Reviewing current studies and previously unpublished research from leading laboratories around the world, Unraveling Lipid Metabolism with Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. With contributions from world-class researchers, the book focuses on the use of microarrays to study and understand lipid metabolism. With coverage that spans the technologies of genomics, transriptomics, and meatabolomics, the text contains reviews of published work, provides a fresh look at new data, and presents previously unpublish.
Lipids play an essential role in cell signaling and subcellular structure. Systematic analysis of the total lipid structure of a cell or organism, the lipodome, can reveal novel avenues of therapeutic intervention and diagnosis. This analysis is best modeled after the lessons learned from proteomics. With contributions from pioneering researchers f
The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Handbook of Algal Science, Microbiology, Technology and Medicine provides a concise introduction to the science, biology, technology and medical use of algae that is structured on the major research fronts of the last four decades, such as algal structures and properties, algal biomedicine, algal genomics, algal toxicology, and algal bioremediation, algal photosystems, algal ecology, algal bioenergy and biofuels. It also covers algal production for biomedicine, algal biomaterials, and algal medicinal foods within these primary sections. All chapters are authored by the leading researchers in their respective research fields. Our society currently faces insurmountable challenges in the areas of biomedicine and energy in the face of increasing global population and diminishing natural resources as well as the growing environmental and economic concerns, such as global warming, greenhouse gas emissions and climate change. Algae offer a way to deal with these challenges and concerns for both sustainable and environment friendly bioenergy production and in biomedicine through the development of crucial biotechnology. Provides an essential interdisciplinary introduction and handbook for all the stakeholders engaged in science, technology and medicine of algae Covers the major research streams of the last four decades, ranging from algal structures, to algal biomedicine and algal bioremediation Fills a significant market opening for an interdisciplinary handbook on algal science, technology and medicine
This book addresses the multidisciplinary challenges in biodiversity conservation with a focus on wildlife crime and how forensic tools can be applied to protect species and preserve ecosystems. Illustrated by numerous case studies covering different geographical regions and species the book introduces to the fundamentals of biodiversity conflicts, outlines the unique challenges of wildlife crime scenes and reviews latest techniques in environmental forensics, such as DNA metagenomics. In addition, the volume explores the socio-economic perspective of biodiversity protection and provides an overview of national and international conservation laws. The field of conservation medicine stresses the importance of recognizing that human health, animal health, and ecosystem health are inextricably interdependent and the book serves as important contribution towards achieving the UN Sustainable Developmental Goals, in particular SDG 15, Life on Land. The book addresses graduate students, scientists and veterinary professionals working in wildlife research and conservation biology.
