Ultrastructural Pathology of the Cell and Matrix
Ultrastructural Pathology of the Cell and Matrix

Author: Feroze N. Ghadially

Publisher: Butterworth-Heinemann

Published: 2013-10-22

Total Pages: 612

ISBN-13: 1483192083

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Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume I present a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the physiological analysis of the nucleus; nuclear matrix, interchromatin, and perichromatin granules; structure and function of centrioles; characteristics of mitochondria; Golgi complex in cell differentiation and neoplasia; and degranulation of rough endoplasmic reticulum. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, scientists, students, and researchers.

Functional Ultrastructure
Functional Ultrastructure

Author: Margit Pavelka

Publisher: Springer Science & Business Media

Published: 2010-07-16

Total Pages: 366

ISBN-13: 3211993908

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The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.

Eosinophil Ultrastructure
Eosinophil Ultrastructure

Author: Rossana C.N. Melo

Publisher: Academic Press

Published: 2023-01-05

Total Pages: 520

ISBN-13: 0128137568

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Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology entirely focuses on eosinophils and their functional roles in inflammation, host defense, and normal homeostatic activities. The book explores the ultrastructure of human eosinophils, highlighting biological processes observed under normal, experimental, and pathological conditions. Created to fill a void in the eosinophil literature, the book includes an extensive array of electron microscopic images that illustrate the diversity of eosinophil morphology. While the atlas is a learning and teaching tool, it is mainly a helpful resource for researchers to identify distinguishing features and structural changes that arise during studies of human eosinophils. The book also covers the ultrastructure of mouse eosinophils under normal and activation conditions and in the context of representative diseases. - Gives guidelines to understand the human eosinophils in studies focused on structural biology, cellular immunology, innate and adaptive immunity, immune responses to pathogens, immunopathology, and inflammatory responses - Provides a core of essential knowledge to identify both immature and mature eosinophils - Comprises a representative compilation of the eosinophil ultrastructure during biological processes, such as activation and degranulation, mostly under experimental conditions - Highlights eosinophil biological processes found in vivo during human diseases, thus providing a link between basic science and clinical aspects - Helps identify distinguishing features and structural changes that arise during studies of human eosinophils after isolation from body fluids, while in cultures, or biopsies - Explains the ultrastructural organization of mature and immature mouse eosinophils, highlighting the similarities/differences between them and human eosinophils

Ultrastructural Pathology of the Cell and Matrix
Ultrastructural Pathology of the Cell and Matrix

Author: Feroze N. Ghadially

Publisher: Butterworth-Heinemann

Published: 2013-10-22

Total Pages: 778

ISBN-13: 1483192091

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Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume 2 presents a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the structure, distribution, and variations of rod-shaped microtubulated bodies; morphology of intracytoplasmic filaments; melanosome-producing and melanosome-containing cells in tumours; myofilaments in striated muscle; and pathological variations in size, shape, and numbers of microbodies. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, pathologists, students, and researchers.

Biological Field Emission Scanning Electron Microscopy, 2 Volume Set
Biological Field Emission Scanning Electron Microscopy, 2 Volume Set

Author: Roland A. Fleck

Publisher: John Wiley & Sons

Published: 2019-04-29

Total Pages: 741

ISBN-13: 1118654064

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The go‐to resource for microscopists on biological applications of field emission gun scanning electron microscopy (FEGSEM) The evolution of scanning electron microscopy technologies and capability over the past few years has revolutionized the biological imaging capabilities of the microscope—giving it the capability to examine surface structures of cellular membranes to reveal the organization of individual proteins across a membrane bilayer and the arrangement of cell cytoskeleton at a nm scale. Most notable are their improvements for field emission scanning electron microscopy (FEGSEM), which when combined with cryo-preparation techniques, has provided insight into a wide range of biological questions including the functionality of bacteria and viruses. This full-colour, must-have book for microscopists traces the development of the biological field emission scanning electron microscopy (FEGSEM) and highlights its current value in biological research as well as its future worth. Biological Field Emission Scanning Electron Microscopy highlights the present capability of the technique and informs the wider biological science community of its application in basic biological research. Starting with the theory and history of FEGSEM, the book offers chapters covering: operation (strengths and weakness, sample selection, handling, limitations, and preparation); Commercial developments and principals from the major FEGSEM manufacturers (Thermo Scientific, JEOL, HITACHI, ZEISS, Tescan); technical developments essential to bioFEGSEM; cryobio FEGSEM; cryo-FIB; FEGSEM digital-tomography; array tomography; public health research; mammalian cells and tissues; digital challenges (image collection, storage, and automated data analysis); and more. Examines the creation of the biological field emission gun scanning electron microscopy (FEGSEM) and discusses its benefits to the biological research community and future value Provides insight into the design and development philosophy behind current instrument manufacturers Covers sample handling, applications, and key supporting techniques Focuses on the biological applications of field emission gun scanning electron microscopy (FEGSEM), covering both plant and animal research Presented in full colour An important part of the Wiley-Royal Microscopical Series, Biological Field Emission Scanning Electron Microscopy is an ideal general resource for experienced academic and industrial users of electron microscopy—specifically, those with a need to understand the application, limitations, and strengths of FEGSEM.

Disorders of Voluntary Muscle
Disorders of Voluntary Muscle

Author: George Karpati

Publisher: Cambridge University Press

Published: 2001-07-12

Total Pages: 800

ISBN-13: 9780521650625

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Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Biological Electron Microscopy
Biological Electron Microscopy

Author: Michael J. Dykstra

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 368

ISBN-13: 146840010X

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In this practical text, the author covers the fundamentals of biological electron microscopy - including fixation, instrumentation, and darkroom work - to provide an excellent introduction to the subject for the advanced undergraduate or graduate student.