Fake fiancée! It was Mike Black's job to keep Candee safe until she testified in court. But his idea of protection meant hiding out with her at his brother's ranch and pretending she was his fiancée! Candee was not impressed—she was a city girl, and confinement in the country was not her idea of fun. The only compensation was living with Mike, but he knew better than to get involved with an irresistible, bubbly blonde. Past experience had taught him it could only lead to one thing: trouble!
Public Diplomacy is now one of the most important concepts in the development and implementation of foreign policy. Trials of Engagement: The Future of US Diplomacy analyses the trials of contemporary practice and identifies factors which will shape a more collaborative future of public diplomacy.
Clinical trials provide essential information needed to turn basic medical research findings into patient treatments. New treatments must be studied in large numbers of humans to find out whether they are effective and to assess any harm that may arise from treatment. There is growing recognition among many stakeholders that the U.S. clinical trials enterprise is unable to keep pace with the national demand for research results. The IOM, along with the Mount Sinai School of Medicine, held a workshop June 27-28, 2011, to engage stakeholders and experts in a discussion about possible solutions to improve public engagement in clinical trials.
On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.
Successful drug development relies on accurate and efficient clinical trials to deliver the best and most effective pharmaceuticals and clinical care to patients. However, the current model for clinical trials is outdated, inefficient and costly. Clinical trials are limited by small sample sizes that do not reflect variations among patients in the real world, financial burdens on participants, and slow processes, and these factors contribute to the disconnect between clinical research and clinical practice. On November 28-29, the National Academies of Sciences, Engineering, and Medicine convened a workshop to investigate the current clinical trials system and explore the potential benefits and challenges of implementing virtual clinical trials as an enhanced alternative for the future. This publication summarizes the presentations and discussions from the workshop.
Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
School Bells and Wedding Bells James Wallin's family is depending on him to find a schoolteacher for their frontier town. Alexandrina Fosgrave seems to be exactly what he needs to help fulfill his father's dream of building a new community. If only James could convince her to accept the position. Alexandrina has traveled west to seek a fresh start, not to find a groom. But after she's stranded in the wilderness with James, he offers her his hand in marriage to protect her reputation. Both are afraid to fall in love, but maybe an engagement of convenience could make them reconsider... Frontier Bachelors: Bold, rugged--and bound to be grooms.
Why has the United States taken such a firm stance against the International Criminal Court (ICC) and expended such diplomatic goodwill in an attempt to dismantle a tribunal that poses no serious risk to its citizens? This book critiques causal ideologies such as American exceptionalism, state sovereignty and laissez-faire capitalism to show how U.S. opposition is driven by pervasive political, legal, historic, military and economic conditioning factors. It shows how U.S. attitudes transcend partisan politics and predicts how the U.S.-ICC relationship will be affected by the economic crisis, shifting international geopolitical power structures, the crisis in the U.S. military, unfolding international human rights law and the “politics of change” promised by the nascent Obama administration. “The United States has been at the centre of international criminal justice initiatives, from Nuremberg to the more recent ad hoc tribunals for the former Yugoslavia, Rwanda, Sierra Leone and Lebanon. But its position has been lukewarm and sometimes, in the darkest days of the Bush administration, outright hostile to the International Criminal Court. Filling a gap in the literature, Dr Mark Kielsgard reviews the history of American policy, analysing the factors that have driven it, making useful and practical suggestions aimed at greater engagement of the United States with the International Criminal Court.” Professor William A. Schabas
Richard Morgan can’t believe his father is considering a rival candy company’s offer to buy out the family business that he loves. Though the confections division is tiny compared to the family’s other ventures, it’s close to his heart. Maybe too close, since the thought of losing it feels like losing his mother all over again. Convinced it’s the best way to continue the Morgan legacy, his father offers Richard control of the company if he’ll secure the family name with a marriage. After a messy, public divorce, marriage is the last thing Richard wants to consider, but according to his father, it’s the only way. Yvette Cruz is the beautiful, savvy mergers and acquisitions rep charged with brokering the buyout agreement between her company and Morgan Confectioners, and Richard Morgan is the only thing standing between her and the promotion she desperately wants. She came from nothing and worked her way to the top of her field, so she’s not about to let his refusal to cooperate stop her from getting what she wants. Corporate rivalry gives way to an unwise attraction when the two meet and spend a night together that ultimately changes their lives forever. Two enemies find love, but a betrayal threatens to tear them apart. Forgiveness and redemption can lead to everything they’ve ever wanted, but some things can’t be forgotten. Sensuality Level: Sensual
