Translation Mechanisms and Control
Author: Michael B. Mathews
Publisher:
Published: 2018-09-30
Total Pages: 499
ISBN-13: 9781621821861
DOWNLOAD EBOOKA subject collection from Cold Spring Harbor Perspectives in Biology.
Posts
Translational Control in Biology and Medicine
Author: Michael Mathews
Publisher: CSHL Press
Published: 2007
Total Pages: 932
ISBN-13: 0879697679
DOWNLOAD EBOOKUpdated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.
Biophysical approaches to translational control of gene expression
Author: Jonathan D. Dinman
Publisher: Springer Science & Business Media
Published: 2012-09-20
Total Pages: 325
ISBN-13: 1461439914
DOWNLOAD EBOOKThis book provides a premier resource on understanding the ribosome's essential nature and how it interacts with other proteins and nucleic acids to control protein synthesis. As one of the central foundations in our understanding of the biology at the molecular level, this topic appeals to a wide audience, from bench researcher to clinician. With the advent of atomic scale structures, methods to visualize and separate individual molecules, and the computational power to model the complex interactions of over a million atoms at once, our understanding of how gene expression is controlled at the level of protein translation is now deeply ensconced in the biophysical realm.
Translational Control
Author: John W. B. Hershey
Publisher:
Published: 1996
Total Pages: 0
ISBN-13: 9780879694586
DOWNLOAD EBOOKA comprehensive account of recent research in translational control and the molecular mechanisms involved, focusing on the numerous control mechanisms observed in eukaryotes. Subjects include basic mechanisms; the role of phosphorylation; regulation by trans-acting proteins; effects of viral infection; and mRNA stability. Other topics include translational control mediated by upstream AUG codons; a comparative view of initiation site selection mechanisms; and genetics of mitochondrial translation. For researchers with interests in gene expression, RNA biology, and protein synthesis. Annotation copyright by Book News, Inc., Portland, OR
Biology of the NMDA Receptor
Author: Antonius M. VanDongen
Publisher: CRC Press
Published: 2008-10-29
Total Pages: 368
ISBN-13: 142004415X
DOWNLOAD EBOOKThe NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written
Molecular Biology of the Cell
Author:
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
DOWNLOAD EBOOKPatterning and Cell Type Specification in the Developing CNS and PNS
Author:
Publisher: Academic Press
Published: 2013-05-06
Total Pages: 993
ISBN-13: 0123973481
DOWNLOAD EBOOKThe genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
RNA-protein Interactions
Author: Kiyoshi Nagai
Publisher: Oxford University Press, USA
Published: 1994
Total Pages: 302
ISBN-13:
DOWNLOAD EBOOKThe study of RNA-protein interactions is crucial to understanding the mechanisms and control of gene expression and protein synthesis. The realization that RNAs are often far more biologically active than was previously appreciated has stimulated a great deal of new research in this field. Uniquely, in this book, the world's leading researchers have collaborated to produce a comprehensive and current review of RNA-protein interactions for all scientists working in this area. Timely, comprehensive, and authoritative, this new Frontiers title will be invaluable for all researchers in molecular biology, biochemistry and structural biology.
Evolution of the Protein Synthesis Machinery and Its Regulation
Author: Greco Hernández
Publisher: Springer
Published: 2016-08-10
Total Pages: 564
ISBN-13: 3319394681
DOWNLOAD EBOOKThe “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
Evolution of Translational Omics
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2012-09-13
Total Pages: 354
ISBN-13: 0309224187
DOWNLOAD EBOOKTechnologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
